sodium 8-anilino-1-naphthalenesulfonate | 34074-97-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: sodium 8-anilino-1-naphthalenesulfonate
• 英文别名: sodium 1-amino-8-naphthalenesulfonate；sodium 1-aminonaphthalene-8-sulfonate；8-amino-naphthalene-1-sulfonic acid ; sodium salt；8-Amino-naphthalin-1-sulfonsaeure; Natriumsalz；Sodium;8-aminonaphthalene-1-sulfonate
• CAS: 34074-97-0
• 化学式: C₁₀H₈NO₃S*Na
• 分子量: 245.234
• InChiKey: HYOVDYVSLXAFAL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.67
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  sodium 8-anilino-1-naphthalenesulfonate 在 盐酸 、 sodium hydroxide 、 氯化亚砜 、 sodium hydrogensulfite 、 sodium thiosulfate 、 N,N-二甲基甲酰胺 、 copper dichloride 、 sodium nitrite 作用下， 以 水 为溶剂， 反应 16.93h， 生成 8-Chlorosulfonyl-2-diazonionaphthalen-1-olate
  参考文献：
  名称：

  1,2-萘醌二叠氮化物-（2）-n-磺酸衍生物的合成及光化学

  摘要：

  1,2-萘醌二叠氮化物-（2）-6-和-7-磺酸酯（7c，7d）首次从1-萘胺-6-和-7-磺酸（1c ，1d）分别通过Bucherer反应，亚硝化，还原，重氮化，磺酰氯，酯化。用这种方法不能成功地合成相应的8-磺酸酯73。在光解过程中，1,2-萘醌二叠氮化物-（2）-6-和-7-磺酸苯基酯（7c，7d）以已知的5相同的方式形成相应的（苯氧基磺酰基）-茚满羧酸（10c，10d）。 -磺酸衍生物10b。与这些异构体不同的是，对4-磺酸酯进行光解在图7a中，另外发生光化学诱导的酯裂解（λ＜320nm）。

  DOI：

  10.1016/s0040-4020(01)85611-8

文献信息

• Quantitative method of determining beryllium or a compound thereof in a sample
  申请人：McCleskey Mark T.

  公开号：US20050221498A1

  公开（公告）日：2005-10-06

  A method of determining beryllium or a beryllium compound thereof in a sample, includes providing a sample suspected of comprising beryllium or a compound thereof, extracting beryllium or a compound thereof from the sample by dissolving in a solution, adding a fluorescent indicator to the solution to thereby bind any beryllium or a compound thereof to the fluorescent indicator, and determining the presence or amount of any beryllium or a compound thereof in the sample by measuring fluorescence.

  一种测定样品中铍或其化合物的方法，包括提供怀疑含有铍或其化合物的样品，通过溶解在溶液中从样品中提取铍或其化合物，向溶液中添加荧光指示剂以将任何铍或其化合物与荧光指示剂结合，通过测量荧光来确定样品中任何铍或其化合物的存在或数量。
• Ink, and recording process using the same
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0381228A2

  公开（公告）日：1990-08-08

  The present invention provides an ink comprising a dye and a liquid medium, wherein said dye is a dye of Formula (I): wherein R₁ and R₂ represent independently an alkyl group, an alkoxy group or an acetylamino group; R₃ represents -SO₃M or a hydrogen atom; R₄ represents a hydrogen atom, -SO₃M or -NHR₅, where R₅ represents a hydrogen atom, a phenyl group that may have a substituent, or a group of the formula where R₆ and R₇ represent independently a hydrogen atom or -C₂H₄OH; M represents an alkali metal, an ammonium group or an organic amonium group; and l, m and n represent independently an integer of 0 or 1.

  本发明提供了一种由染料和液体介质组成的墨水，其中所述染料是式 (I) 的染料： 其中 R₁ 和 R₂ 独立地代表烷基、烷氧基或乙酰氨基； R₃ 代表-SO₃M 或氢原子； R₄ 代表氢原子、-SO₃M 或-NHR₅，其中 R₅ 代表氢原子、可能具有取代基的苯基或式(I)的基团 其中 R₆ 和 R₇ 独立地代表氢原子或-C₂H₄OH； M 代表碱金属、铵基团或有机铵基团；以及 l、m 和 n 独立地代表 0 或 1 的整数。
• Erdmann, Justus Liebigs Annalen der Chemie, 1888, vol. 247, p. 353
  作者：Erdmann

  DOI：——

  日期：——
• Development of Potent and Selective Inhibitors of <i>ecto</i>-5′-Nucleotidase Based on an Anthraquinone Scaffold
  作者：Younis Baqi、Sang-Yong Lee、Jamshed Iqbal、Peter Ripphausen、Anne Lehr、Anja B. Scheiff、Herbert Zimmermann、Jürgen Bajorath、Christa E. Müller

  DOI：10.1021/jm901851t

  日期：2010.3.11

  ecto-5'-Nucleotidase (eN, CD73) plays it major role in controlling extracellular adenosine levels. eN inhibitors have potential its novel drugs, for example, for the treatment of cancer. In the present study, we synthesized and investigated a series of 55 anthraquinone derivatives as potential inhibitors of eN, I I of which are novel compounds and another I I of which had previously been described but have now been synthesized by all improved method. We identified several potent inhibitors of rat eN. The most potent compounds were 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9, 10-dioxo-9, 10-dihydroanthracene-2-sulfonate (45, PSB-0952, K-i = 260 nM) and 1-amino-4-[2-anthracenylamino]-9, 10-dioxo-9, 10-dihydroanthracene-2-sulfonate (52, PSB-0963, 150 nM), with 52 being the most potent eN inhibitor described to date. Selected compounds were further characterized and found to exhibit a competitive mechanism of inhibition. Investigations of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the P2Y receptor subtypes P2Y(2), P2Y(4), P2Y(6), and P2Y(12) showed that compound 45 exhibited the highest degree of selectivity (> 150-fold).
• Seifullina, I. I.; Skorokhod, L. S.; Minin, V. V., Russian Journal of Inorganic Chemistry, 1991, vol. 36, p. 386 - 391
  作者：Seifullina, I. I.、Skorokhod, L. S.、Minin, V. V.、Larin, G. M.

  DOI：——

  日期：——