8-acetyloxy-4-methylnaphtho[2,3-b]pyran-2-one | 75550-12-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: 8-acetyloxy-4-methylnaphtho[2,3-b]pyran-2-one
• 英文别名: (4-methyl-2-oxobenzo[g]chromen-8-yl) acetate
• CAS: 75550-12-8
• 化学式: C₁₆H₁₂O₄
• 分子量: 268.269
• InChiKey: YVSWWWYWXILGEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.18
• 重原子数：
  20.0
• 可旋转键数：
  1.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  56.51
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  8-acetyloxy-4-methylnaphtho[2,3-b]pyran-2-one 在 三氯化铝 作用下， 反应 2.0h， 以30.4%的产率得到9-acetyl-4-methyl-8-hydroxynaphtho[2,3-b]pyran-2-one
  参考文献：
  名称：

  Regioselective synthesis and photooxygenations of furonaphthopyrones starting from 2,7-naphthalenediol

  摘要：

  Three angular furonaphthopyrones 4, 9, 12 were regioselectively synthesized starting from 2,7-naphthalenediol in three steps, respectively. An easy separation of Pechmann condensation products 1 and 2 of 2,7-naphthalenediol with ethyl acetoacetate was described. The photooxygenations of 4, 12 were investigated and a hydroperoxide 18 was isolated and fully characterized. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00845-4
• 作为产物：
  描述：

  8-hydroxy-4-methyl-2H-naphtho<2,3-b>-pyran-2-one 、 乙酸酐 反应 3.0h， 以70.5%的产率得到8-acetyloxy-4-methylnaphtho[2,3-b]pyran-2-one
  参考文献：
  名称：

  Regioselective synthesis and photooxygenations of furonaphthopyrones starting from 2,7-naphthalenediol

  摘要：

  Three angular furonaphthopyrones 4, 9, 12 were regioselectively synthesized starting from 2,7-naphthalenediol in three steps, respectively. An easy separation of Pechmann condensation products 1 and 2 of 2,7-naphthalenediol with ethyl acetoacetate was described. The photooxygenations of 4, 12 were investigated and a hydroperoxide 18 was isolated and fully characterized. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00845-4

文献信息

• PARDANANI J. H.; SETHNA S., J. INST. CHEM.(INDIA), 1980, 52, NO 2, 61-70
  作者：PARDANANI J. H.、 SETHNA S.

  DOI：——

  日期：——
• Regioselective synthesis and photooxygenations of furonaphthopyrones starting from 2,7-naphthalenediol
  作者：Zhi-Fu Tao、Xuhong Qian、Mingcai Fan

  DOI：10.1016/s0040-4020(97)00845-4

  日期：1997.9

  Three angular furonaphthopyrones 4, 9, 12 were regioselectively synthesized starting from 2,7-naphthalenediol in three steps, respectively. An easy separation of Pechmann condensation products 1 and 2 of 2,7-naphthalenediol with ethyl acetoacetate was described. The photooxygenations of 4, 12 were investigated and a hydroperoxide 18 was isolated and fully characterized. (C) 1997 Elsevier Science Ltd.