1,1'-(dibenzo[b,d]furan-2,8-diyl)bis(2-(3,5-dimethoxyphenylamino)ethanone) | 1393734-83-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: 1,1'-(dibenzo[b,d]furan-2,8-diyl)bis(2-(3,5-dimethoxyphenylamino)ethanone)
• 英文别名: 2-(3,5-Dimethoxyanilino)-1-[8-[2-(3,5-dimethoxyanilino)acetyl]dibenzofuran-2-yl]ethanone；2-(3,5-dimethoxyanilino)-1-[8-[2-(3,5-dimethoxyanilino)acetyl]dibenzofuran-2-yl]ethanone
• CAS: 1393734-83-2
• 化学式: C₃₂H₃₀N₂O₇
• 分子量: 554.599
• InChiKey: DUHQDOGONWFMNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  41
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  1,1'-(dibenzo[b,d]furan-2,8-diyl)bis(2-(3,5-dimethoxyphenylamino)ethanone) 在 三氟乙酸 、 potassium hydroxide 、 三氯氧磷 作用下， 以 甲醇 为溶剂， 反应 6.83h， 生成 3,3'-(dibenzo[b,d]furan-2,8-diyl)bis(4,6-dimethoxy-1H-indole-7-carbaldehyde)
  参考文献：
  名称：

  Synthesis of new di-(3-indolyl)arenes

  摘要：

  1,4-Di-(3-indolyl)benzene 6 and 2,8-di-(3-indolyl)dibenzofuran 12 were synthesized from 1,4-diacetylbenzene and 2,8-diacetyldibenzofuran, respectively, via indole synthetic strategies. Investigation into the acid-catalysed formation of macrocyclic systems from these di-(3-indolyl)arenes led to the development of the 18-membered macrocycle 14 from the diindolylbenzene 6, which was capable of undergoing complexation with nickel(II) ions. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.06.074
• 作为产物：
  描述：

  1-(8-乙酰基二苯并呋喃-2-基)乙酮 在 溴 、 碳酸氢钠 、 溶剂黄146 作用下， 以 乙醇 为溶剂， 反应 9.0h， 生成 1,1'-(dibenzo[b,d]furan-2,8-diyl)bis(2-(3,5-dimethoxyphenylamino)ethanone)
  参考文献：
  名称：

  Synthesis of new di-(3-indolyl)arenes

  摘要：

  1,4-Di-(3-indolyl)benzene 6 and 2,8-di-(3-indolyl)dibenzofuran 12 were synthesized from 1,4-diacetylbenzene and 2,8-diacetyldibenzofuran, respectively, via indole synthetic strategies. Investigation into the acid-catalysed formation of macrocyclic systems from these di-(3-indolyl)arenes led to the development of the 18-membered macrocycle 14 from the diindolylbenzene 6, which was capable of undergoing complexation with nickel(II) ions. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.06.074

文献信息

• Synthesis of new di-(3-indolyl)arenes
  作者：Ibrahim F. Sengul、Kasey Wood、Paul K. Bowyer、Mohan Bhadbhade、Rui Chen、Naresh Kumar、David StC. Black

  DOI：10.1016/j.tet.2012.06.074

  日期：2012.9

  1,4-Di-(3-indolyl)benzene 6 and 2,8-di-(3-indolyl)dibenzofuran 12 were synthesized from 1,4-diacetylbenzene and 2,8-diacetyldibenzofuran, respectively, via indole synthetic strategies. Investigation into the acid-catalysed formation of macrocyclic systems from these di-(3-indolyl)arenes led to the development of the 18-membered macrocycle 14 from the diindolylbenzene 6, which was capable of undergoing complexation with nickel(II) ions. (C) 2012 Elsevier Ltd. All rights reserved.