| 1581728-47-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• CAS: 1581728-47-3
• 化学式: C₂₈H₂₂N₂O₃
• 分子量: 434.494
• InChiKey: VGMUGQYWKNWOQN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.42
• 重原子数：
  33.0
• 可旋转键数：
  5.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  69.15
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  1-(1-adamantyl)-2-diazo-1-ethanone 、 在 三苯基膦 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以45%的产率得到2-[2-(adamantan-1-yl)-2-oxoethylidenehydrazono]-5-(4-ethylphenyl)-4-[3-(4-ethylphenyl)quinoxalin-2-yl]furan-3(2H)-one
  参考文献：
  名称：

  Diaza-Wittig reaction of 4,5-disubstituted furan-2,3-diones with triphenylphosphazenes derived from 3-R-adamantanoyldiazomethane

  摘要：

  Reactions of 1-(3-R-adamantan-1-yl)-2-(triphenyl-lambda(5)-phosphanylidenehydrazono)ethanones with 4,5-disubstituted furan-2,3-diones gave 2-[2-(3-R-1-adamantan-1-yl)-5-acyl-2-oxoethylidenehydrazono]-4-R-2-furan-3(2H)-ones.

  DOI：

  10.1134/s1070428014120124

文献信息

• Synthesis of stable 1,4-diionic organophosphorus compounds from the reaction between triphenylphosphine and diaroylacetylenes in the presence of 5-aryl-4-quinoxalin-2-yl-furan-2,3-diones
  作者：Natalya Yu. Lisovenko、Artem V. Dryahlov、Maxsim V. Dmitriev

  DOI：10.1080/10426507.2017.1295962

  日期：2017.8.3

  GRAPHICAL ABSTRACT ABSTRACT Novel 1,4-diionic organophosphorus compounds have been obtained efficiently from the one-pot three-component reaction of triphenylphosphine, diaroylacetylenes and 5-aryl-4-quinoxalin-2-yl-furan-2,3-diones in 1,2-dichloroethane. The synthesized compounds were characterized by different spectroscopic methods and their structure was confirmed in one case by single crystal X-ray

  图形摘要 摘要 从三苯基膦、二芳酰基乙炔和 5-芳基-4-喹喔啉-2-基-呋喃-2,3-二酮在 1 中的一锅三组分反应中有效地获得了新型 1,4-二离子有机磷化合物。 ,2-二氯乙烷。合成的化合物通过不同的光谱方法进行了表征，并且在一种情况下通过单晶 X 射线衍射证实了它们的结构。
• Three-component reaction of 5-aryl-4-(quinoxalin-2-yl)-furan-2,3-diones, acetylenedicarboxylic acid dimethyl ester, and triphenylphosphine
  作者：N. Yu. Lisovenko、A. V. Dryahlov、M. V. Dmitriev

  DOI：10.1134/s1070428016080157

  日期：2016.8

  Three-component synthesis from 5-aryl-4-(quinoxalin-2-yl)furan-2,3-diones, acetylenedicarboxylic acid dimethyl ester, and triphenylphosphine afforded methyl esters of 1,6-dioxaspiro[4.4]nona-3,7-diene-4-carboxylic and 4H-furo[3,2-c]pyran-3-carboxylic acids.

  由5-芳基-4-（喹喔啉-2-基）呋喃-2,3-二酮，乙炔二羧酸二甲酯和三苯膦三组分合成，得到1,6-二氧杂螺[4.4] nona-3,7的甲酯-二烯-4-羧酸和4 H-呋喃[3,2 - c ]吡喃-3-羧酸。
• Three-Component Synthesis of Dimethyl 7-Aryl-8-(3-Arylquinoxalin-2-yl)-2-(R-Imino)-9-Oxo-1,6-Dioxa-Spiro[4.4]Nona-3,7-Diene-3,4-Dicarboxylates
  作者：N. Yu. Lisovenko、A. V. Dryahlov

  DOI：10.1007/s10593-014-1439-x

  日期：2014.4

  We have developed a method for the synthesis of dimethyl 7-aryl-8-(3-arylquinoxalin-2-yl)-2-(R-imino)-9-oxo-1,6-dioxaspiro[4.4]nona-3,7-diene-3,4-dicarboxylates, based on a three-component reaction of 5-aryl-4-(quinoxalin-2-yl)furan-2,3-diones, 1-adamantylisocyanide or D3/4-methylphenylisocyanide, and dimethyl acetylenedicarboxylate.