5-Mercapto-naphthol | 77204-20-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-Mercapto-naphthol
• 英文别名: 5-Hydroxy-naphthalinthiol-(1)；5-Mercapto-[1]naphthol；5-Hydroxy-1-mercapto-naphthalin；5-Hydroxy-naphthyl-(1)-mercaptan；5-Sulfanylnaphthalen-1-ol
• CAS: 77204-20-7
• 化学式: C₁₀H₈OS
• 分子量: 176.239
• InChiKey: AUFVXJQTUICZHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  21.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-Mercapto-naphthol 在 碘 作用下， 以 甲醇 、 水 为溶剂， 生成 di(5-hydroxy-1-naphthyl)disulfide
  参考文献：
  名称：

  Effects of oxygen–sulfur substitution on glycosaminoglycan-priming naphthoxylosides

  摘要：

  Three series of sulfur-containing analogs to the selectively antiproliferative 2-(6-hydroxynaphthyl) beta-D-xylopyranoside were synthesized and their biological properties investigated. A short, general route to hydroxynaphthyl disulfides from dihydroxy-naphthalenes was developed to utilize the disulfide bond as a sulfur-selective protecting group to enable the orthogonal protection of hydroxyls and thiols. The results indicate that hydrophobic, uncharged oxygen-sulfur substituted naphthoxylosides are taken up by calls and initiate priming of GAG chains to a greater extent compared to the oxygen analogs. No correlation between priming ability and antiproliferative activity was observed. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2007.05.008
• 作为产物：
  描述：

  Ethyl-(5-mercapto-naphthyl-1)-carbonat 在 sodium sulfide 、 sodium hydroxide 作用下， 生成 5-Mercapto-naphthol
  参考文献：
  名称：

  Rennert, Chemische Berichte, 1915, vol. 48, p. 468

  摘要：

  DOI：

文献信息

• LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD
  申请人：IWAI Yu

  公开号：US20080087183A1

  公开（公告）日：2008-04-17

  A lithographic printing plate precursor includes an image-recording layer which is capable of being removed with at least one of printing ink and dampening water and contains a compound represented by the following formula (I), a sensitizing dye and a compound having at least one addition-polymerizable ethylenically unsaturated bond: wherein R 1 represents a monovalent substituent, R 2 , R 3 , R 4 , R 5 and R 6 each independently represents a hydrogen atom, a halogen atom or a monovalent substituent, and X − represents an anion.

  一种光刻印刷版前体包括一个图像记录层，该层能够被印刷油墨和润湿水中的至少一种去除，并含有以下式（I）所代表的化合物，一种敏化染料和至少一种含有至少一个加成聚合乙烯基不饱和键的化合物：其中R1代表一个单价取代基，R2、R3、R4、R5和R6各自独立地代表氢原子、卤素原子或单价取代基，X⁻代表一个阴离子。
• Lithographic printing plate precursor and lithographic printing method
  申请人：FUJIFILM Corporation

  公开号：EP1872942A2

  公开（公告）日：2008-01-02

  A lithographic printing plate precursor includes an image-recording layer which is capable of being removed with at least one of printing ink and dampening water and contains a compound represented by the following formula (I), a sensitizing dye and a compound having at least one addition-polymerizable ethylenically unsaturated bond: wherein R1 represents a monovalent substituent, R2, R3, R4, R5 and R6 each independently represents a hydrogen atom, a halogen atom or a monovalent substituent, and X represents an anion.

  平版印刷板原版包括一个图像记录层，该层可使用印刷油墨和润湿水中的至少一种去除，并含有下式（I）所代表的化合物、感光染料和至少具有一个可加成聚合的乙烯不饱和键的化合物： 其中 R1 代表一价取代基，R2、R3、R4、R5 和 R6 各自独立地代表氢原子、卤素原子或一价取代基，X 代表阴离子。
• Einflu� der Stellungsisomerie und Methylierung am Schwefel auf die Farbe von Merkapto- ?-Naphtholazofarbstoffen
  作者：Egon Jusa、Leo Gr�n

  DOI：10.1007/bf01518672

  日期：1934.12
• Watson; Dutt, Journal of the Chemical Society, 1922, vol. 121, p. 2415
  作者：Watson、Dutt

  DOI：——

  日期：——
• NEIDLEIN R.; SCHAEFER G., ARCH. PHARM., 1981, 314, NO 1, 91-93
  作者：NEIDLEIN R.、 SCHAEFER G.

  DOI：——

  日期：——