α-phenylethylammonium sulfate | 6707-17-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: α-phenylethylammonium sulfate
• 英文别名: (+/-)-1-phenyl-ethylamine; sulfate；(+/-)-1-Phenyl-aethylamin; Sulfat；1-Phenylethanamine;sulfuric acid
• CAS: 6707-17-1；26848-02-2；42817-63-0；107146-37-2；136383-00-1；143800-98-0
• 化学式: 2C₈H₁₁N*H₂O₄S
• 分子量: 340.444
• InChiKey: NIZOVBNYAOCDCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.05
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  109
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  α-phenylethylammonium sulfate 在 sodium hydroxide 作用下， 生成 α-苯乙胺
  参考文献：
  名称：

  由二芳基亚磺酰胺合成伯胺的新方法

  摘要：

  在水解后，将有机金属试剂加到二芳基磺酰胺中得到伯胺，说明了将磺酰胺用作氨基保护基。

  DOI：

  10.1016/s0040-4039(00)84883-2
• 作为产物：
  描述：

  (S,S)-(-)-N,N-Bis(alpha-methylbenzyl)sulfamide 在 吡啶 作用下， 生成 α-phenylethylammonium sulfate
  参考文献：
  名称：

  由二芳基亚磺酰胺合成伯胺的新方法

  摘要：

  在水解后，将有机金属试剂加到二芳基磺酰胺中得到伯胺，说明了将磺酰胺用作氨基保护基。

  DOI：

  10.1016/s0040-4039(00)84883-2

文献信息

• Resolution of Racemic Organic Acids with (1S, 4S)-4[3,4-Dichlorophenyl]-1,2,3,4-Tetrahydro-N-Methyl-1-Naphthaloneamine
  申请人：Satyanarayana Chava

  公开号：US20090253932A1

  公开（公告）日：2009-10-08

  The present invention relates to novel chiral resolving agents and a process for resolution of racemic organic acids and their derivatives of the formula (+, −)—R 1 R 2 CHCOOR3 with Cis-(1S,4S)-4[3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Cis-(1R,4R)-isomer as well as Trans-(1S,4R)-4[3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Trans-(1R,4S)-isomer.

  本发明涉及新颖的手性分离剂以及用于分离具有式（+，−）—R1R2CHCOOR3的消旋有机酸及其衍生物的方法，所述方法使用顺式-(1S,4S)-4[3,4-二氯苯基]-1,2,3,4-四氢-N-甲基-1-萘酮胺及其顺式-(1R,4R)-异构体，以及反式-(1S,4R)-4[3,4-二氯苯基]-1,2,3,4-四氢-N-甲基-1-萘酮胺及其反式-(1R,4S)-异构体。
• Preparation and some physicochemical properties of benzylammonium sulfates
  作者：R. E. Khoma、A. A. Ennan、V. O. Gelmboldt、O. V. Shishkin、V. N. Baumer、A. V. Mazepa、Yu. E. Brusilovskii

  DOI：10.1134/s1070363214040069

  日期：2014.4

  New method of preparation of multisubstituted benzylammonium cations via interaction in the SO2-L-H2O systems (L is benzylamine, alpha-phenylethylamine, N,N-dimethylbenzylamine, or dibenzylamine) has been developed. The products have been studied by X-ray diffraction, IR, Raman spectroscopy, and mass spectrometry.
• RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE
  申请人：Matrix Laboratories Ltd

  公开号：EP1831132A2

  公开（公告）日：2007-09-12
• US3941814A
  申请人：——

  公开号：US3941814A

  公开（公告）日：1976-03-02
• [EN] RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE<br/>[FR] RESOLUTION D'ACIDES ORGANIQUES RACEMIQUES AVEC (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTALONEAMINE
  申请人：MATRIX LAB LTD

  公开号：WO2006013581A2

  公开（公告）日：2006-02-09

  The present invention relates to novel chiral resolving agents and a process for resolution of racemic organic acids and their derivatives of the formula (+, -)-R1R2CHCOOR3 with Cis- (1S,4S)-4 [3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Cis-(lR,4R)-isomer as well as Trans-(1S,4R)-4[3,4-dichlorophenyl]-1,2,3,4-tetrahydro-N-methyl-1-naphthaloneamine and its Trans-(1R,4S)-isomer.