3H-heptadecafluorobicyclo[4.4.0]decane | 93289-98-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: 3H-heptadecafluorobicyclo[4.4.0]decane
• 英文别名: Undecafluoro(6H)tetralin；1,1,2,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-heptadecafluoro-2H-naphthalene
• CAS: 93289-98-6
• 化学式: C₁₀HF₁₇
• 分子量: 444.091
• InChiKey: DEAPYABULJRQCX-UHFFFAOYSA-N

物化性质

• 沸点：
  153.1±40.0 °C(Predicted)
• 密度：
  1.79±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  27
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  17

反应信息

• 作为产物：
  描述：

  1,3,4,5,6,7,8-heptafluoronaphthalene 在 五氟化锑 作用下， 生成 3H-heptadecafluorobicyclo[4.4.0]decane
  参考文献：
  名称：

  Pozdnyakovich,Yu.V.; Shteingarts,V.D., Journal of Organic Chemistry USSR (English Translation), 1978, vol. 14, p. 2069 - 2070

  摘要：

  DOI：

文献信息

• Microfluidic devices and systems
  申请人：Sphere Fluidics Limited

  公开号：US10247655B2

  公开（公告）日：2019-04-02

  A method of label-free cell or particle sorting in a microfluidic device includes providing a stream of aqueous droplets in oil in a channel of the microfluidic device, wherein at least some of the droplets include cells or particles and illuminating the stream from a first direction. Then, one detects scattered light from cells or particles within said aqueous droplets in a second direction. Next, one determines a number of the cells or particles in each droplet from the scattered light and sorts the aqueous droplets into differentiated streams. Notably, the refractive index of said oil is modified to closely match a refractive index of the aqueous droplets to reduce light scattered from boundaries of the droplets. A volume of the droplets can also controlled.

  一种在微流体设备中进行无标记细胞或颗粒分选的方法，包括在微流体设备的通道中提供油中的水液滴流，其中至少一些液滴包括细胞或颗粒，并从第一方向照射该液滴流。然后，检测所述水滴中的细胞或颗粒沿第二方向发出的散射光。然后，根据散射光确定每个液滴中细胞或颗粒的数量，并将水液滴分拣成不同的液流。值得注意的是，所述油的折射率被修改为与水液滴的折射率紧密匹配，以减少从液滴边界散射的光。液滴的体积也可以控制。
• METHOD FOR SORTING CELLS AND/OR PARTICLES
  申请人：Sphere Fluidics Limited

  公开号：EP3027322B1

  公开（公告）日：2020-04-08
• EMULSION
  申请人：SPHERE FLUIDICS LIMITED

  公开号：US20160169788A1

  公开（公告）日：2016-06-16

  The present invention provides an emulsion for sorting droplets in a microfluidic device, the emulsion comprising: a discontinuous aqueous phase; and a continuous oil phase; wherein said aqueous phase comprises at least one analyte, said oil phase comprises a fluorous oil and a refractive index modifying compound comprising at least one aromatic ring, and the refractive index of said aqueous phase and the refractive index of said oil phase are substantially matched.
• MICROFLUIDIC DEVICES AND SYSTEMS
  申请人：Sphere Fluidics Limited

  公开号：US20160252446A1

  公开（公告）日：2016-09-01

  We describe a method of label-free cell and/or particle sorting in a microfluidic device, the method comprising; providing a stream of aqueous droplets in oil in a channel of said microfluidic device, wherein at least some of said droplets include cells and/or particles illuminating said stream from a first direction; detecting, for example, scattered light from cells and/or particles within said aqueous droplets in a second direction; determining, for example, a number of said cells and/or particles in each droplet from the scattered light; and sorting said aqueous droplets into one of a plurality of differentiated streams responsive to said determined number. The method further comprises modifying a refractive index of said oil to more closely match a refractive index of said aqueous droplets to reduce light scattered from boundaries of said droplets. Optionally a volume of the droplets is also controlled. In embodiments the oil is fluorous oil. We describe examples of preferred refractive index modifying compounds.
• US9513207B2
  申请人：——

  公开号：US9513207B2

  公开（公告）日：2016-12-06