ergost-3-one | 59461-38-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: ergost-3-one
• 英文别名: (24S)-5α-Erogstan-3-on；5α-ergostan-3-one；5α-Ergostan-3-on；5α-Ergostanon-(3)；5a-Ergostan-3-one；(5S,8R,9S,10S,13R,14S,17R)-17-[(2R,5S)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
• CAS: 59461-38-0
• 化学式: C₂₈H₄₈O
• 分子量: 400.689
• InChiKey: DDJMOMHMVFXEQF-BYHPMSKYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  ergost-3-one 在 氯仿 、 溴 作用下， 生成 2α-bromo-5α-ergostanone-(3)
  参考文献：
  名称：

  350.固醇类的研究。第十六部分。（a）麦角固醇的分子式。（b）用二氧化锰和硫酸氧化麦角固醇和α-二氢麦角固醇

  摘要：

  DOI：

  10.1039/jr9320002400
• 作为产物：
  描述：

  ergost-22-en-3-one 在 chromium(VI) oxide 、 溶剂黄146 、 乙酸乙酯 、 铂 作用下， 生成 ergost-3-one
  参考文献：
  名称：

  380.分子旋转差异法在类固醇上的应用。第十部分“ β-二氢麦角固醇”。

  摘要：

  DOI：

  10.1039/jr9490001771

文献信息

• Measuring national ‘emerging technology’ capabilities
  作者：Alan L Porter、J David Roessner、Xiao-Yin Jin、Nils C Newman

  DOI：10.3152/147154302781781001

  日期：2002.6.1

  How can national capabilities to develop emerging technologies be measured? We use INSPEC and EI Compendex class codes to examine 33 countries' research and development activity. We select candidate emerging technologies based on the Rand Corporation's categories. We screen these to tally those that show strong recent, and increasing, R&D publication rates. The resulting measures show strong convergence; indeed, their lack of divergence is unsettling. Our measures suggest that China now stands forth as an ‘emerging technology’ research power comparable to Germany, the UK, and France. A number of other nations evidence a striking lack of R&D activity, posing questions about their longer-range high-tech competitiveness.

  如何衡量国家开发新兴技术的能力？我们使用 INSPEC 和 EI Compendex 类别代码来研究 33 个国家的研发活动。我们根据兰德公司的分类选择候选新兴技术。我们对这些技术进行筛选，以统计出那些近期研发成果发表率较高且不断上升的技术。由此得出的衡量指标显示出很强的趋同性；事实上，它们之间缺乏差异的情况令人不安。我们的测量结果表明，中国现在已成为可与德国、英国和法国相媲美的 "新兴技术 "研究大国。其他一些国家则明显缺乏研发活动，这对它们在高科技领域的长期竞争力提出了质疑。
• Antiwear Tribofilm Formation on Steel Surfaces Lubricated With Gear Oil Containing Borate, Phosphorus, and Sulfur Additives
  作者：K. Komvopoulos、V. Chiaro、B. Pakter、E. S. Yamaguchi、P. R. Ryason

  DOI：10.1080/10402000208982589

  日期：2002.1

  The formation of antiwear tribofilms plays a critical role in the longevity of automotive gears. The focus of this experimental study was on the lubrication efficacy of gear oils with different contents of borate-, phosphorus-, and sulfur-containing additives leading to the formation of protective tribofilms. Experiments were performed with AISI 52100 steel balls sliding against AISI 52100 steel disks in baths of different oils at ambient (similar to32degreesC) and elevated (similar to100degreesC) temperatures under load and speed conditions favoring sliding in the boundary lubrication regime. Friction coefficient responses accompanied by electrical contact voltage measurements provided real-time information about the formation and durability of the antiwear tribofilms. The wear resistance of the tribochemical films was quantified by wear rate data obtained from surface profilometry measurements of wear tracks on the disk specimens and sliding tests performed at ambient temperatures after the formation of the tribofilms during elevated-temperature sliding. Results indicate a strong dependence of tribofilm formation on temperature and type of additives. The slightly lower friction and higher wear resistance obtained at elevated temperatures with blended oils is attributed to the increased chemical reactivity of additives containing borate, phosphorus, and sulfur, leading to the formation of durable tribofilms. Relatively higher wear resistance and faster tribofilm formation were obtained with the borate-enriched gear oil formulations.
• Thrust-Washer Evaluation of Self-Lubricating PS304 Composite Coatings in High Temperature Sliding Contact
  作者：Thierry A. Blanchet、Jong-Hwan Kim、Salvadore J. Calabrese、Christopher Dellacorte

  DOI：10.1080/10402000208982579

  日期：2002.1

  PS304 self-lubricating composite coatings were successfully deposited on steel substrates at various plasma spray facilities using mixtures blended from commercially obtained constituent particles. Coatings were evaluated in thrust-washer tests against Inconel X-750 at low contact pressures to 40kPa, sliding speed of 5.4m/s, and either ambient temperature or 500 degreesC chosen to simulate conditions in air foil bearings during startup and shutdown contact. Wear factors for all PS304 coatings tested, regardless of contact pressure and temperature, ranged from 1-3*10(-4) mm(3)/Nm while coefficients of friction of approximately mu = 0.5 were measured in all cases. While wear and friction behavior of PS304 in air foil bearings appear to have been simulated, surface roughening was observed in these thrust-washer tests which used continuous sliding contact, as opposed to the evolution of smoother surfaces observed in high-temperature foil bearings experiencing cyclic startup/shutdown. Wear-induced surface smoothening of PS304 was additionally simulated in thrust-washer tests with sliding contact instead imposed intermittently.
• Reindel; Walter, Justus Liebigs Annalen der Chemie, 1927, vol. 460, p. 212,221
  作者：Reindel、Walter

  DOI：——

  日期：——