1-氯-2-[2-(4-甲基苯基)乙烯基]苯 | 58566-19-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: 1-氯-2-[2-(4-甲基苯基)乙烯基]苯
• 英文名称: 2-chloro 4'-methyl stilbene
• 英文别名: 1-chloro-2-[2-(4-methylphenyl)ethenyl]benzene
• CAS: 58566-19-1
• 化学式: C₁₅H₁₃Cl
• 分子量: 228.721
• InChiKey: DTAHFSLJKXEZDO-UHFFFAOYSA-N

物化性质

• 熔点：
  37 °C(Solv: ethanol (64-17-5))
• 沸点：
  339.6±22.0 °C(Predicted)
• 密度：
  1.138±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-氯-2-[2-(4-甲基苯基)乙烯基]苯 在 N-溴代丁二酰亚胺(NBS) 、 偶氮二异丁腈 作用下， 以 四氯化碳 为溶剂， 反应 6.0h， 以18%的产率得到2-chloro 4'-bromomethyl stilbene
  参考文献：
  名称：

  Synthesis and calcium antagonistic activity of diethyl styrylbenzylphosphonates

  摘要：

  Twenty-three new phosphonic ester derivatives of stilbene exhibiting structural analogies with fostedil are described. Examination of calcium antagonism showed that this activity could not be increased by introducing electron-withdrawing, electron-releasing or lipophilic substituents. Only compounds containing fluorine at the 2 or 4 positions exhibited similar activity to the model.

  DOI：

  10.1016/0223-5234(94)90204-6
• 作为产物：
  描述：

  4-甲基苄基膦酸二乙酯 、 2-氯苯甲醛 在 sodium hydride 作用下， 以 乙二醇二甲醚 为溶剂， 反应 10.0h， 以14%的产率得到1-氯-2-[2-(4-甲基苯基)乙烯基]苯
  参考文献：
  名称：

  Synthesis and calcium antagonistic activity of diethyl styrylbenzylphosphonates

  摘要：

  Twenty-three new phosphonic ester derivatives of stilbene exhibiting structural analogies with fostedil are described. Examination of calcium antagonism showed that this activity could not be increased by introducing electron-withdrawing, electron-releasing or lipophilic substituents. Only compounds containing fluorine at the 2 or 4 positions exhibited similar activity to the model.

  DOI：

  10.1016/0223-5234(94)90204-6

文献信息

• Iminophosphine palladium(II) complexes: synthesis, characterization, and application in Heck cross-coupling reaction of aryl bromides
  作者：Mustafa Kemal Yılmaz、Bilgehan Güzel

  DOI：10.1002/aoc.3158

  日期：2014.7

  Palladium(II) complexes containing phosphorus and nitrogen donor atoms (iminophosphine), dichloridoN‐[2‐(diphenylphosphino)benzylidene]‐2‐trifluoromethylaniline}palladium(II) 1, dichloridoN‐[2‐(diphenylphosphino)benzylidene]‐3‐trifluoromethylaniline}palladium(II) 2, dichloridoN‐[2‐(diphenylphosphino)benzylidene]‐2‐methylaniline}palladium(II) 3, dichloridoN‐[2‐(diphenylphosphino)benzylidene]‐3‐

  含磷和氮供体原子（亚氨基膦），二氯基 N- [2-（二苯基膦基）亚苄基] -2-三氟甲基苯胺}钯（II）配合物，二氯基钯（II）1， N- [2-（二苯基膦基）亚苄基] -3-三氟甲基苯胺}合钯（II）2，dichlorido ñ - [2-（二苯基膦基）亚苄基] -2-甲基苯胺}合钯（II）3，dichlorido ñ - [2-（二苯基膦基）亚苄基] -3-甲基苯胺}钯（II）4已成功合成，并通过FT-IR和NMR（1 H，31 P，19 F和13C）光谱技术。这些配合物首先在溴苯和苯乙烯的反应中进行了测试，以确定最佳的偶联反应条件，然后成功地用作活化和失活的芳基溴化物与苯乙烯衍生物和几种丙烯酸酯的Heck交叉偶联反应的催化剂。版权所有©2014 John Wiley＆Sons，Ltd.
• Immobilized Pd on (<i>S</i>)-methyl histidinate-modified multi-walled carbon nanotubes: a powerful and recyclable catalyst for Mizoroki-Heck and Suzuki-Miyaura C-C cross-coupling reactions in green solvents and under mild conditions
  作者：Abdol R. Hajipour、Zahra Khorsandi

  DOI：10.1002/aoc.3425

  日期：2016.5

  thermogravimetric and elemental analyses. This new air‐ and moisture‐stable phosphine‐free palladium catalyst was found to be highly active and reusable in Mizoroki–Heck and Suzuki–Miyaura cross‐coupling reactions in poly(ethylene glycol) and aqueous ethanol as green solvents using an extremely small amount of palladium under mild conditions. Copyright © 2016 John Wiley & Sons, Ltd.

  使用固定在多壁碳纳米管表面的（S）-组氨酸甲酯上的固定钯合成了稳定，功能强大的多相钯催化剂。通过傅里叶变换红外光谱和X射线光电子能谱，透射电子显微镜，X射线粉末衍射和电感耦合等离子体，热重分析和元素分析对催化剂进行了表征。发现这种新型的对空气和湿气稳定的无膦钯催化剂具有很高的活性，并且可以在极少量的聚乙二醇和乙醇水溶液作为绿色溶剂的Mizoroki–Heck和Suzuki–Miyaura交叉偶联反应中重用。在温和条件下的钯。版权所有©2016 John Wiley＆Sons，Ltd.
• 10.1021/acs.orglett.4c01715
  作者：Zhen, Ying-Ying、Qu, Jian-Ping、Kang, Yan-Biao

  DOI：10.1021/acs.orglett.4c01715

  日期：——

  feasible in many cases. The energy transfer (EnT) E/Z-photoisomerization might yield the Z-isomers. In this work, CBZ6 was proven to be an EnT photocatalyst for the E → Z-isomerization of C–C or C–N double bonds. The transformations of in situ generated Z-isomers of oximes and stilbenes consequently afforded the desired reversed Beckmann rearrangement products and phenanthrenes, respectively.

  考虑到化学选择性的区域选择性， Z-异构体和E-异构体的反应通常是不同的。 Z-异构体的合成在许多情况下是不可行的。能量转移 (EnT) E / Z光异构化可能会产生Z异构体。在这项工作中， CBZ6被证明是一种用于 C-C 或 C-N 双键E → Z异构化的 EnT 光催化剂。原位生成的肟和茋的Z-异构体的转化因此分别提供了所需的反向贝克曼重排产物和菲。
• Synthesis and Characterization of Pd(II) and Ru(II) Complexes of Tetradentate N,N,N,N-(Diphosphinomethyl)amine Ligands: Catalytic Properties in Transfer Hydrogenation and Heck Coupling Reactions
  作者：Serhan Uruş、Mustafa Keleş、Seda Köşker Akkaya

  DOI：10.3987/com-20-14260

  日期：——

  Tetradentate N,N,N,N-(diphosphinomethyl)amine ligands and their Pd(II) and Ru(II) complexes were synthesized under a nitrogen atmosphere using Schlenk technique. The synthesized ligands and the complexes were characterized with H-1- and P-31-NMR, FT-IR, TG/DTA, and elemental analysis techniques. Pd(II) Complexes were used as catalysts in Heck coupling reactions and Ru(II) complexes were tried in transfer hydrogenation reactions of acetophenone derivatives. According to the results, L4-Pd(II) complex showed the best catalytic activity in the Heck coupling reaction of p-methylbromobenzene with o-chlorostyrene. It was confirmed that the reduction of bromo and chloroacetophenones in all catalysts the conversions were higher. The results showed that Ru(II) complexes as efficient catalysts and up to 99% conversions was occurred with bromo and chloro acetophenones in K2CO3/isopropyl alcohol media at 80 degrees C.
• PHOTOCROSSLINKABLE POLYMER, INSULATING FILM, PLANARIZATION FILM, LYOPHILIC/LIQUID REPELLENT PATTERNED FILM, AND ORGANIC FIELD EFFECT TRANSISTOR DEVICE COMPRISING SAME
  申请人：TOSOH CORPORATION

  公开号：US20210135115A1

  公开（公告）日：2021-05-06

  Provided is a resin which is excellent in terms of solubility in common solvents, crosslinking temperature, time required for crosslinking, solvent resistance (cracking resistance), breakdown voltage, leakage current, solvent wettability, and planarity in cases where the resin is formed into a thin film. A resin which comprises repeating units represented by formula (1) and formula (2), and wherein the repeating unit represented by formula (2) is contained in an amount of 20% by mole or more relative to the total amount of the repeating units represented by formula (1) and formula (2).