5,5'-氧基二(戊腈) | 5392-06-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 5,5'-氧基二(戊腈)
• 英文名称: 6-oxa-undecanedinitrile
• 英文别名: 4.4'-Dicyan-dibutylaether；6-Oxa-undecandinitril；Bis(4-cyanobutyl) ether；5-(4-cyanobutoxy)pentanenitrile
• CAS: 5392-06-3
• 化学式: C₁₀H₁₆N₂O
• 分子量: 180.25
• InChiKey: SZJIJFGCCHVXPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  56.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5,5'-氧基二(戊腈) 在 sodium hydroxide 作用下， 生成 6-氧杂-十一烷二酸
  参考文献：
  名称：

  Alexander; Schniepp, Journal of the American Chemical Society, 1948, vol. 70, p. 1842

  摘要：

  DOI：
• 作为产物：
  描述：

  4,4'-氧基双(丁-1-醇) 在 吡啶 、 乙醇 、 三溴化磷 作用下， 生成 5,5'-氧基二(戊腈)
  参考文献：
  名称：

  Rethinking the Analysis of Ethnic Residential Patterns: Segregation, Isolation, or Concentration Thresholds in Auckland, New Zealand?

  摘要：

  Data from the 1996 New Zealand Census on ethnicity in Auckland Urban Area are used to illustrate a new approach to measuring spatial separation. The traditionally employed single‐number indices are found wanting and a method based on thresholds is introduced. This provides more detailed information on the geography of ethnic groups that is consistent with the requirements for testing hypotheses regarding the relationship between social and spatial distance. The results show that (with a few exceptions) Polynesian groups were more encapsulated groups in Auckland than were Asian and European groups, and that most of the European groups—along with the “host society,” the New Zealand Europeans—were not spatially exposed to members of the Polynesian and Asian groups.

  DOI：

  10.1111/j.1538-4632.2002.tb01087.x

文献信息

• Regioselective biotransformations of dinitriles using Rhodococcus sp. AJ2701
  作者：Otto Meth-Cohn、Mei-Xiang Wang

  DOI：10.1039/a703904b

  日期：——

  or γ-sulfur is present. Hydrolysis of N,N-bis(2-cyanoethyl)anilines 4h–j takes place slowly affording exclusively the monoacids 5h–j while the monocyano amides 5o–p are obtained as the sole isolable product from rapid hydrolysis of the corresponding N,N-bis(2-cyanomethyl)butylamine 4o and N,N-bis(3-cyanopropyl)butylamine 4p. Higher homologues of arylimino- and butylimino-dinitriles are inert to enzymatic

  使用Rhodococcus sp在非常温和的条件下选择性地水解了多种二腈。AJ270。脂族二腈NC [CH 2 ] n CN 1进行区域选择性水解，得到的单官能酸2在腈官能团之间最多具有4个亚甲基，而n  > 4的单酸2获得的二酸3的收率很好。当将氧置于氰基的β，γ或δ或β-或γ-上时，带有醚键或硫化物键的二腈NC [CH 2 ] n X [CH 2 ] n CN 4被有效地转化为一元酸5。存在硫。N，N的水解双（2-氰乙基）苯胺的4H-j取而monocyano酰胺0-50 p如从相应的快速水解的唯一可分离产物获得缓慢发生，得到专门的一元酸5H-J Ñ，Ñ双（2-氰基）丁胺4o和N，N-双（3-氰基丙基）丁胺4p。芳基-和丁基亚氨基-二腈的较高同系物对酶促水解是惰性的。多种其它脂族二腈的已被容易地转化成单酸以良好至优异的产率，除了ö -phenylenediacetonitrile其给出ø
• Rationalisation of the regioselective hydrolysis of aliphatic dinitriles with Rhodococcus rhodochrous AJ270
  作者：Otto Meth-Cohn、Mei-Xiang Wang

  DOI：10.1039/a700859g

  日期：——

  Aliphatic dinitriles undergo regioselective hydrolysis with the title organism to give monoacids with up to four methylenes between the nitrile functions (optimally 2–3) or when either an oxygen is placed β, γ or δ to the nitrile (δ-placement being optimal) or β or γ (optimally γ) but not δ sulfur substituents are present; nitrogen substituents appear to behave as for oxygen but suffer a steric limitation of the size of the nitrogen substituent.

  脂肪族二腈在该有机体的催化下发生区域选择性水解，生成单酸，腈基之间最多可有四个亚甲基（最优为2-3个），或者当氧原子位于腈的β、γ或δ位时（以δ位最佳），或者在β或γ位时（最优为γ），但如果存在δ位的硫取代基则不行；氮取代基的行为类似于氧，但受到氮取代基尺寸的空间限制。
• Reppe et al., Justus Liebigs Annalen der Chemie, 1955, vol. 596, p. 65
  作者：Reppe et al.

  DOI：——

  日期：——
• Moschkin, Voprosy Ispol'zovaniya Pentozansoderzhashchego Syr'ya, Trudy Vsesoyuznogo Soveshchaniya, 1955, p. 225,247
  作者：Moschkin

  DOI：——

  日期：——
• DE886447
  申请人：——

  公开号：——

  公开（公告）日：——