N-(Cyclohexyl)-N-(2-chloroethyl)-aminomethylphosphonic Acid | 77822-19-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: N-(Cyclohexyl)-N-(2-chloroethyl)-aminomethylphosphonic Acid
• 英文别名: [2-chloroethyl(cyclohexyl)amino]methylphosphonic acid
• CAS: 77822-19-6
• 化学式: C₉H₁₉ClNO₃P
• 分子量: 255.682
• InChiKey: KULUJPCDRSZCMH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N-(2-氯乙基)环己胺 、 亚磷酸 在 盐酸 、 聚合甲醛 作用下， 以 水 为溶剂， 生成 N-(Cyclohexyl)-N-(2-chloroethyl)-aminomethylphosphonic Acid
  参考文献：
  名称：

  Novel N-(alkyl)-N-(2-haloethyl)-aminomethylphosphonic acids, a method

  摘要：

  淀粉醚衍生物是通过将淀粉基物质与N-(2-卤乙基)亚胺基双(亚甲基)二膦酸或N-(烷基)-N-(2-卤乙基)氨甲基膦酸反应制备而成。这些衍生物包含氨基膦酸基团(或其盐)作为偶极子取代基，其中包括一个或两个阴离子亚甲基膦酸基团结合到阳离子氮上。它们的阳离子或阴离子特性可以通过将适当的阳离子或阴离子基团引入，要么通过与氨基膦酸试剂同时反应，要么在氨基膦酸反应之前或之后连续反应来增加。它们在造纸过程中作为颜料保留助剂特别有用。N-(烷基)-N-(2-卤乙基)氨甲基膦酸是一种新的试剂，通过将N-(2-卤乙基)烷基胺盐酸盐(例如N-(2-氯乙基)乙胺盐酸盐或N-(2-氯乙基)环己胺盐酸盐)，磷酸，甲醛和水盐酸在110℃至125℃下反应1至6小时制备而成。

  公开号：

  US04297299A1

文献信息

• Novel zwitterion polygalactomannan ether derivatives and a method for
  申请人：National Starch and Chemical Corporation

  公开号：US04276414A1

  公开（公告）日：1981-06-30

  Zwitterion polygalactomannan ether derivatives are prepared by reacting a polygalactomannan gum, such as guar gum or locust bean gum, with N-(2-haloethyl)iminobis(methylene)diphosphonic acid or with a N-(alkyl)-N-(2-haloethyl)aminomethylphosphonic acid. The derivatives contain aminophosphonic acid groups (or their salts) as zwitterion substituents which consist of either one or two anionic methylene phosphonic acid groups bound to a cationic nitrogen. Modified derivatives containing non-ionic, anionic, cationic, or cationogenic substituents may also be prepared.

  通过将聚半乳糖甘聚糖胶（如瓜尔胶或洋车前子胶）与N-(2-卤乙基)亚基双(亚甲基)二膦酸或N-(烷基)-N-(2-卤乙基)氨甲基膦酸反应来制备带有氨基膦酸基团（或其盐）的缁特离子聚半乳糖甘聚糖醚衍生物。这些衍生物包含氨基膦酸基团（或其盐）作为缁特离子取代基，其中包括一个或两个阴离子亚甲基膦酸基团与一个阳离子氮结合。还可以制备含有非离子、阴离子、阳离子或阳离子生成基团的改性衍生物。
• Novel starch ether derivatives, a method for the preparation thereof
  申请人：National Starch and Chemical Corporation

  公开号：US04260738A1

  公开（公告）日：1981-04-07

  Starch ether derivatives are prepared by reacting a starch base with N-(2-haloethyl)iminobis(methylene)diphosphonic acid or with a N-(alkyl)-N-(2-haloethyl)aminomethylphosphonic acid. The derivatives contain aminophosphonic acid groups (or their salts) as zwitterion substituents which consist of either one or two anionic methylene phosphonic acid groups bound to a cationic nitrogen. Their cationic or anionic characteristics may be increased by introducing suitable cationic or anionic groups either by simultaneous reaction with the aminophosphonic acid reagent or by consecutive reaction either prior to or subsequent to the aminophosphonic acid reaction. They are especially useful as pigment retention aids in paper making processes.

  淀粉醚衍生物是通过将淀粉基与N-(2-卤乙基)亚胺基双(亚甲基)二膦酸或N-(烷基)-N-(2-卤乙基)氨基甲基膦酸反应制备而成。这些衍生物含有氨基膦酸基团(或其盐)作为离子双替位基，其中包括一个或两个阴离子亚甲基膦酸基团与一个阳离子氮原子结合。它们的阳离子或阴离子特性可以通过同时与氨基膦酸试剂反应或在氨基膦酸反应之前或之后进行连续反应引入适当的阳离子或阴离子基团来增加。它们在造纸工艺中作为颜料保留助剂尤其有用。
• Novel starch ether derivatives, a method for the preparation thereof and their use in paper
  申请人：National Starch and Chemical Corporation

  公开号：EP0025830A1

  公开（公告）日：1981-04-01

  Starch ether derivatives are prepared by reacting a starch base with N-(2-haloethyl)iminobis (methylene)diphosphonic acid or with a N-(alkyl)-N -(2-haloethyl)aminomethylphosphonic acid. The derivatives contain aminophosphonic acid groups (or their salts) as zwitterion substituents which consist of either one or two anionic methylene phosphonic acid groups bound to a cationic nitrogen. Their cationic or anionic characteristics may be increased by introducing suitable cationic or anionic groups either by simultaneous reaction with the aminophosphonic acid reagent or by consecutive reaction either prior to or subsequent to the aminophosphonic acid reaction. They are especially useful as pigment retention aids in papermaking processes.

  淀粉醚衍生物是通过淀粉基与 N-(2-卤乙基)亚氨基双(亚甲基)二膦酸或 N-(烷基)-N-(2-卤乙基)氨基甲基膦酸反应而制备的。这些衍生物含有氨基膦酸基团（或其盐类）作为齐氮取代基，由一个或两个与阳离子氮结合的阴离子亚甲基膦酸基团组成。通过与氨基膦酸试剂同时反应或在氨基膦酸反应之前或之后连续反应，引入适当的阳离子或阴离子基团，可增加它们的阳离子或阴离子特性。它们在造纸工艺中作为颜料助留剂尤其有用。
• US4243479A
  申请人：——

  公开号：US4243479A

  公开（公告）日：1981-01-06
• US4260738A
  申请人：——

  公开号：US4260738A

  公开（公告）日：1981-04-07