Verimol D | 212516-37-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: Verimol D
• 英文别名: (2S,3S)-1,2-bis(4-methoxyphenyl)butane-1,3-diol
• CAS: 212516-37-5
• 化学式: C₁₈H₂₂O₄
• 分子量: 302.37
• InChiKey: KKTBJMXEKPXZHK-FMOQSIQZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,2-二甲氧基丙烷 、 Verimol D 在 potassium carbonate 、 对甲苯磺酸 作用下， 生成 反-4,4'-二甲氧基芪 、 (4S,5S,6S)-4,5-bis(4-methoxyphenyl)-2,2,6-trimethyl-1,3-dioxane
  参考文献：
  名称：

  Novel Phenylpropanoids and Lignans from Illicium verum

  摘要：

  Nine new phenylpropanoids (2-7, 10. 12, and 14) and two compounds representing novel structural classes of 7-O-8' and 7-O-8'.8-O-7' lignans (8 and 9, respectively) have been isolated from Illicium verum and their structures established by two-dimensional NMR. Most of these compounds appear to be biogenetically derived from threo-anethole glycol: relative stereochemistries for some members of this series were established by NOESY; absolute stereochemistries of others were determined by formation of Mosher esters.

  DOI：

  10.1021/np9800553

文献信息

• Novel Phenylpropanoids and Lignans from <i>Illicium </i><i>v</i><i>erum</i>
  作者：Lai-King Sy、Geoffrey D. Brown

  DOI：10.1021/np9800553

  日期：1998.8.1

  Nine new phenylpropanoids (2-7, 10. 12, and 14) and two compounds representing novel structural classes of 7-O-8' and 7-O-8'.8-O-7' lignans (8 and 9, respectively) have been isolated from Illicium verum and their structures established by two-dimensional NMR. Most of these compounds appear to be biogenetically derived from threo-anethole glycol: relative stereochemistries for some members of this series were established by NOESY; absolute stereochemistries of others were determined by formation of Mosher esters.