anthracene 1,5-disulphonate sodium salt | 13189-75-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: anthracene 1,5-disulphonate sodium salt
• 英文别名: anthracene-1,5-disulphonate sodium salt；anthracene-1,5-disulfonate sodium salt；disodium 1,5-anthracenedisulphonate；sodium anthracene-1,5-disulfonate；1,5-anthracene disulfonic acid disodium salt；Dinatrium-anthracen-disulfonat-(1.5)
• CAS: 13189-75-8
• 化学式: C₁₄H₈O₆S₂*2Na
• 分子量: 382.325
• InChiKey: SQSPWDTZMSMJOS-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -1.19
• 重原子数：
  23.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  114.4
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  diphenylarsane 、 anthracene 1,5-disulphonate sodium salt 生成 Anthrylen-(1.5)-bis-diphenylarsin
  参考文献：
  名称：

  Terti�re Arsine durch Umsetzung von Kaliumdiphenylarsid mit Salzen aromatischer Sulfons�uren

  摘要：

  DOI：

  10.1007/bf01154364
• 作为产物：
  描述：

  anthraquinone-1,5-disulfonate 在 ammonium hydroxide 、 锌 作用下， 生成 anthracene 1,5-disulphonate sodium salt
  参考文献：
  名称：

  Bhattacharya, Subhash C.; Rohatgi-Mukherjee, K. K., Journal of the Indian Chemical Society, 1986, vol. 63, p. 50 - 55

  摘要：

  DOI：

文献信息

• Deciphering the fluorescence resonance energy transfer from denatured transport protein to anthracene 1,5 disulphonate in reverse micellar environment
  作者：Dipti Singharoy、Subhash Chandra Bhattacharya

  DOI：10.1016/j.molstruc.2017.08.046

  日期：2017.12

  been used for this purpose and corresponding Fӧrster-type resonance energy transfer (FRET) from tryptophan residues to 1,5-AS indicates that 1,5-AS binds in the vicinity of the tryptophan residue (BSA and HSA) with equal strength. Indication of protein damage from fluorescence data and its confirmation has been measured from CD measurement. Molecular modeling study hereby plays a crucial role to predict

  摘要 本工作采用 AOT 反胶束介质内的受约束环境效应来收集蒽 1,5 二磺酸钠 (1,5-AS) 与模型转运蛋白、牛血清白蛋白 (BSA) 之间的能量转移效率信息。 , 和人血清白蛋白 (HSA)。为此目的使用了稳态、时间分辨荧光和圆二色性技术，相应的 Fӧrster 型共振能量转移 (FRET) 从色氨酸残基到 1,5-AS 表明 1,5-AS 结合在具有相同强度的色氨酸残基（BSA 和 HSA）。来自荧光数据的蛋白质损伤指示及其确认已通过 CD 测量进行测量。因此，分子建模研究在预测蛋白质环境内探针的最小能量对接构象方面起着至关重要的作用。从对接构象来看，1,5-AS 与 BSA/HSA 的色氨酸部分之间的距离成功地解释了它们之间存在 FRET 的可能性。BSA 和 HSA 之间的比较建模研究，其中 1,5-AS 将它们的结合位点分配在特定氨基酸内，在支持 FRET 研究方面起着至关重要的作用。
• Correlation of FRET efficiency with conformational changes of proteins in ionic and nonionic surfactant environment
  作者：Dipti Singharoy、Soumya Sundar Mati、Soumyadipta Rakshit、Sayantani Chall、Subhash Chandra Bhattacharya

  DOI：10.1016/j.molliq.2015.10.038

  日期：2016.1

  We have studied the effect of interaction of surfactants on the FRET process in aqueous solution from transport proteins, BSA and HSA to the probe molecule, sodium salt of anthracene 1,5-disulphonate (1,5-AS). Cationic surfactant CTAB and gemini, anionic surfactant SDS and nonionic surfactant igepal-630 have been used for our investigation as surfactants and micellar solution. In organized media denaturation of protein occurs. Denaturation of protein has also been observed in presence of 1,5-AS. This has been established from steady state, time resolved fluorescence and circular dichroism (CD) studies in homogeneous and heterogeneous environments. Helecity calculations from CD spectra have also supported the results. Nonionic and ionic micellar solutions have been found to directly affect the protein helicity and the FRET parameters. The FRET parameters and denaturation of proteins in homogeneous and heterogeneous media have been compared. (C) 2015 Elsevier B.V. All rights reserved.