4-(1-methyl-1-p-xylylcyclobutane-3-yl)-2-(2-hydroxy-5-bromobenzolidenehydrazino)thiazole | 588710-16-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-(1-methyl-1-p-xylylcyclobutane-3-yl)-2-(2-hydroxy-5-bromobenzolidenehydrazino)thiazole
• CAS: 588710-16-1
• 化学式: C₂₃H₂₄BrN₃OS
• 分子量: 470.433
• InChiKey: GFUGQUWMTMAPAA-UHFFFAOYSA-N

物化性质

• 熔点：
  168 °C
• 沸点：
  592.5±60.0 °C(Predicted)
• 密度：
  1.42±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.51
• 重原子数：
  29.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  57.51
• 氢给体数：
  2.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  4-(1-methyl-1-p-xylylcyclobutane-3-yl)-2-(2-hydroxy-5-bromobenzolidenehydrazino)thiazole 、 zinc(II) acetate dihydrate 以 乙醇 为溶剂， 以63%的产率得到zinc;4-bromo-2-[(E)-[[4-[3-(2,5-dimethylphenyl)-3-methylcyclobutyl]-1,3-thiazol-2-yl]hydrazinylidene]methyl]phenolate
  参考文献：
  名称：

  Cyclobutane and Thiazole Substituted Schiff Base Ligands and Their Cobalt(II), Copper(II), Nickel(II), and Zinc(II) Complexes

  摘要：

  Two novel bidentate Schiff base ligands containing cyclobutane and 2,4-disubstituted thiazole rings, 4-(1-methyl-1-p-xylylcyclobutane-3-yl)-2-(2-hydroxybenzylidenehydrazino)thiazole ((LH)-H-1), 4-(1-methyl-1-p-xylylcyclobutane-3-yl)-2-(2-hydroxy-5-bromobenzylidenehydrazino)thiazole ((LH)-H-2), and their mononuclear complexes with a 1:2 metalaigand ratio have been prepared with acetate salts of Co(II), Cu(II), Ni(II) and Zn(II) in ethanol. The authenticity of the ligands and their complexes have been established by microanalyses, IR, H-1 and C-13 NMR spectra, and by magnetic susceptibility measurements. The thermal properties of all complexes have been studied by TGA and DSC techniques. All the complexes were found to be mononuclear.

  DOI：

  10.1081/sim-120020330