2-dodecyloxy-6-formylnaphthalene | 308123-05-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-dodecyloxy-6-formylnaphthalene
• 英文别名: 6-dodecyloxy-2-naphthaldehyde；6-dodecyloxynaphthalene-2-carbaldehyde；6-Dodecoxynaphthalene-2-carbaldehyde
• CAS: 308123-05-9
• 化学式: C₂₃H₃₂O₂
• 分子量: 340.506
• InChiKey: MRFMKBGVXJFPSV-UHFFFAOYSA-N

物化性质

• 沸点：
  478.0±18.0 °C(predicted)
• 密度：
  0.999±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  25
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-dodecyloxy-6-formylnaphthalene 在 potassium tert-butylate 、 四丁基氢氧化铵 作用下， 以 四氢呋喃 、 甲醇 、 叔丁醇 为溶剂， 反应 0.75h， 生成 (Z)-2,3-bis(6-dodecoxynaphthalen-2-yl)prop-2-enenitrile
  参考文献：
  名称：

  Synthesis and Characterization of Novel Optically Active Polyarylene Vinylenes with Controlled Effective Conjugation Length

  摘要：

  New chiral and soluble binaphthyl derivatives (12 and 13) endowed with carboxaldehyde or cyanomethyl functional groups have been prepared as suitable building blocks for the synthesis by Knoevenagel condensation of a series of optically active block copolymers (1-7) with controlled effective conjugation length. A variety of functionalized co-monomers (14-19) have been prepared by different synthetic procedures to be used in further polymerization reactions with binaphthyl derivatives 12 and 13. Depending upon the nature of the co-monomers, it is possible to tune the wavelength of the new polymers, which is very close to that of the respective repeating units. Fluorescence measurements on polymers 1-3 reveal a strong blue-green emission with Stokes shifts of 74-107 nm. Theoretical calculations at the semiempirical AM-1 level have been carried out on model compounds, and the calculated torsion angles are in agreement with the electronic spectra data. Finally, the redox properties of the polymers prepared (1-7) were determined by cyclic voltammetry, and an amphoteric behavior with oxidation potentials ranging from 1.1 to 1.6 V and reduction potentials close to -1.5 V was found.

  DOI：

  10.1021/jo000761k
• 作为产物：
  描述：

  6-溴-2-萘酚 在 正丁基锂 、 sodium iodide 、 potassium hydroxide 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 24.0h， 生成 2-dodecyloxy-6-formylnaphthalene
  参考文献：
  名称：

  二烷氧基萘封端二乙烯基苯对OTFT的链长效应

  摘要：

  由二乙烯基苯核心单元和两侧的烷氧基萘组成的新型有机半导体，1,4-bis-2-(6-octyloxy)naphthalen-2-ylvinylbenzo (BONVB), 1,4-bis-2-(6-癸氧基)萘2-基乙烯基苯(BDNVB)和1,4-双-2-(6-十二烷基氧基)萘-2-基乙烯基苯(BDDNVB)通过Wittig反应合成。所得BONVB、BDNVB和BDDNVB的结构经FT-IR和质谱确认。由于相邻分子之间的紧密堆积结构，薄膜的紫外吸收显示出 H 聚集体和 J 聚集体。通过 X 射线衍射 (XRD) 和原子力显微镜 (AFM) 对真空蒸发薄膜的表征表明，烷氧基的链长影响结晶度和形貌。含辛氧基的 BONVB 的迁移率为 0.011 cm 2 /V·s，开/关比为 1.31 × 10 5 ，

  DOI：

  10.5012/bkcs.2012.33.2.420

文献信息

• Variation of the energy gap in fullerene-based dendrons: competitive versus sequential energy and electron transfer events
  作者：José L. Segura、Rafael Gómez、Nazario Martín、Chuping Luo、Angela Swartz、Dirk M. Guldi

  DOI：10.1039/b100397f

  日期：——

  Artificial molecular models, based on rigid dendrimeric meta-substituted phenylenevinylene moieties bearing different electron donating groups and the electron acceptor C60, were probed in an effort to gain control over a sequential versus a competitive scenario in energy and electron transfer events.

  基于刚性树枝状聚合物的人工分子模型 间位取代的亚苯基亚乙烯基部分带有不同的 给电子基团和电子受体 C60 试图获得对顺序与顺序的控制 能量和电子转移事件中的竞争场景。
• Cyclic polypeptide with antibiotic activity and a process for preparation thereof
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP0729974A1

  公开（公告）日：1996-09-04

  A polypeptide compound of the following general formula : whereinR1 is acyl group, R2 is acyloxy, R3 is hydrogen and R4 is hydrogen and a pharmaceutically acceptable salt thereof, a process for its preparation and pharmaceutical compositions comprising it. The invention relates also to use of the compound for the manufacture of a medicament for treating or preventing infectious diseases.

  以下是通用式的多肽化合物： 其中，R1是酰基，R2是酰氧基，R3是氢，R4是氢，以及其药学上可接受的盐，制备该化合物的方法以及包含它的制药组合物。本发明还涉及使用该化合物制造治疗或预防传染病的药物。
• Pharmaceutical composition against Pneumocystis carinii
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP0486011A2

  公开（公告）日：1992-05-20

  Use of a polypeptide compound of the formula : wherein R¹ is hydrogen or acyl group, R² is hydroxy or acyloxy, R³ is hydrogen, hydroxy or hydroxysulfonyloxy, R⁴ is hydrogen or carbamoyl, and R⁵ and R⁶ are each hydrogen or hydroxy, with proviso that (i) R² is acyloxy, when R³ is hydrogen, and (ii) R⁵ is hydrogen, when R⁶ is hydrogen, or a pharmaceutically acceptable salt thereof for the preparation of a medicament for the prevention and/or the treatment of Pneumocystis carinii infection.

  使用式 ： 其中 R¹ 是氢或酰基 R² 是羟基或酰氧基、 R³ 是氢、羟基或羟基磺酰氧基、 R⁴ 是氢或氨基甲酰基，以及 R⁵ 和 R⁶ 均为氢或羟基、 但条件是 (i) 当 R³ 为氢时，R² 为酰氧基，以及 (ii) 当 R⁵ 是氢时，R⁶ 是氢、 或其药学上可接受的盐，用于制备预防和/或治疗卡氏肺囊虫感染的药物。
• Rigid Dendritic Donor−Acceptor Ensembles:  Control over Energy and Electron Transduction
  作者：Dirk M. Guldi、Angela Swartz、Chuping Luo、Rafael Gómez、José L. Segura、Nazario Martín

  DOI：10.1021/ja012694x

  日期：2002.9.1

  Several generations of phenylenevinylene dendrons, covalently attached to a C-60 core, have been developed as synthetic model systems with hierarchical, fine-tuned architectures. End-capping of these dendritic spacers with dibutylaniline or dodecyloxynaphthalene, as antennas/electron donors, yielded new donor-bridge-acceptor ensembles in which one, two, or four donors are allocated at the peripheral positions of the well-defined dendrons, while the electron accepting fullerene is placed at the focal point of the dendron. On the basis of our cyclic voltammetry experiments, which disclose a single anodic oxidation and several cathodic reduction processes, we rule out significant, long-range couplings between the fullerene core and the end-standing donors in their ground-state configuration. Photophysical investigations, on the other hand, show that upon photoexcitation an efficient and rapid transfer of singlet excited-state energy (6 x 10(10) to 2.5 N 10(12) s(-1)) controls the reactivity of the initially excited antenna portion. Spectroscopic and kinetic evidence suggests that yet a second contribution, that is, an intramolecular electron-transfer, exists, affording C-60(.-) -dendron(.+) with quantum yields (Phi) as high as 0.76 and lifetimes (tau) that are on the order of hundreds of nanoseconds (220-725 ns). Variation of the energy gap modulates the interplay of these two pathways (i.e., competition or sequence between energy and electron transfer).
• Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP0462531B1

  公开（公告）日：1996-10-02