N-(3-aminopropyl)hexylamine | 7748-29-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(3-aminopropyl)hexylamine
• 英文别名: N-hexyl-propanediyldiamine；N-Hexyl-propandiyldiamin；n-Hexyl-1,3-propanediamine；N'-hexylpropane-1,3-diamine
• CAS: 7748-29-0
• 化学式: C₉H₂₂N₂
• 分子量: 158.287
• InChiKey: UUWPMNGNEAEOIR-UHFFFAOYSA-N

物化性质

• 沸点：
  110 °C(Press: 9 Torr)
• 密度：
  0.834±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  11
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-(3-aminopropyl)hexylamine 在 乙醚 、 苯酚 作用下， 生成 N-(3-benz[c]acridin-7-ylamino-propyl)-N-hexyl-acetamide
  参考文献：
  名称：

  Synthetic Amebicides. III. 7-(3-Octylaminopropylamino)-benz[c]acridine (PAA-2056) and Related 7-(Alkyl- and Aralkylaminoalkylamino)-benz[c]acridines^1,2

  摘要：

  DOI：

  10.1021/ja01534a057
• 作为产物：
  描述：

  3-己氨基丙腈 在 乙醇 、 氨 、 镍 作用下， 120.0 ℃ 、17.16 MPa 条件下， 生成 N-(3-aminopropyl)hexylamine
  参考文献：
  名称：

  4-Thiazolidones. IV. The Preparation of Some 3-Alkylaminoalkyl-2-aryl Derivatives

  摘要：

  DOI：

  10.1021/ja01178a023
• 作为试剂：
  描述：

  4-methoxyheptachlorostyrene oxide 在 五氯化磷 、 N-(3-aminopropyl)hexylamine 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 4.0h， 生成 4-methoxyheptachlorostyrene 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Identification of 4-Hydroxyheptachlorostyrene in Polar Bear Plasma and Its Binding Affinity to Transthyretin:  A Metabolite of Octachlorostyrene?

  摘要：

  A new compound, 4-hydroxyheptachlorostyrene (4-OH-HpCS), was identified as a major component in the chlorinated phenolic compound fraction of polar bear plasma. The structure was hypothesized to be 4-OH-HpCS based on mass spectral interpretation, the assumption that it was a metabolite of octachlorostyrene, and the similarity of the structure to hydroxylated polychlorinated biphenyls (OH-PCBs) identified in plasma. High-resolution, electron impact (EI) ionization mass spectrometry of the methylated compound indicated a molecular formula of C9H3OCl7 and major fragment ions of [M - 15](+), [M - 35](+), and [M - 43](+), which was a mass spectral pattern identical to a synthesized and methylated 4-OH-HpCS standard. The identity was further confirmed by matching gas chromatography (GC) retention times on three different GC columns of differing polarity. Levels of 4-OH-HpCS ranged from 2.89 to 22.9 ng/g wet weight in polar bear plasma (N=30) and constituted between 3.8 and 24.8% of the total quantified level of chlorinated phenolic compounds. The mean ratio of 4-OH-HpCS to CB153 concentrations in polar bear plasma samples was 0.712 (+/- 0.580 SD), which suggests selective retention of the 4-OH-HpCS in plasma. The presumed mechanism of retention involves 4-OH-HpCS binding to transthyretin (TTR). The presence of TTR was confirmed for the first time in polar bear plasma by binding of I-125-thyroxine (T-4), the natural ligand of TTR, to separated plasma proteins. The binding affinity of 4-OH-HpCS to human TTR was tested and found to be 1.1 relative to T-4. This suggests that 4-OH-HpCS has the potential to disrupt T-4 and retinol transport, by analogy to OH-PCBs with similar structure. Metabolism of octachlorostyrene (OCS) is the most likely source of 4-OH-HpCS. DCS was shown to be present at low concentrations in polar bear tissues as well as in plasma of ringed seal, the principal prey species of polar hears. The ratio of 4-OH-HpCS to OCS and 4-OH-HpCS to CB153 concentrations were 150- and 44-fold higher in polar bear plasma than in ringed seal plasma. This study indicates that the phenolic metabolites of relatively minor contaminants possess the capacity to bind to circulating proteins, and their significance as potential endocrine-disrupting agents may be underestimated.

  DOI：

  10.1021/es001134f

文献信息

• ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE
  申请人：Burckhardt Urs

  公开号：US20100101455A1

  公开（公告）日：2010-04-29

  The present invention relates in a first consideration to aldimines of formula (I). Said aldimines are particularly suitable as latent hardeners in curable compositions, particularly compositions comprising one or two-component isocyanate groups. Due to the presence of the reactive group, they can be converted to compounds of the formulas (X) and (XII) comprising aldimine groups, implementing a further consideration of the present invention. The aldimines, or the compounds comprising aldimine groups, can be used primarily in adhesive and sealant materials, but also in coatings, and can be produced easily from readily available source materials, and have good thermal stability. The tertiary amino group thereof has a surprisingly low alkalinity and can in some cases have a catalytic effect in chemical reaction systems.

  本发明涉及公式(I)的醛胺，首先考虑这些醛胺作为可固化组合物的潜在固化剂，特别是含有一种或两种异氰酸基团的组合物。由于具有反应性基团，它们可以转化为公式(X)和(XII)的化合物，包括醛胺基团，这是本发明的进一步考虑。这些醛胺或含有醛胺基团的化合物主要可用于粘合剂和密封材料，也可用于涂料，并且可以从易得的原料中轻松制备，并具有良好的热稳定性。其中的三级氨基具有惊人的低碱度，在某些情况下可以在化学反应系统中具有催化作用。
• ALDIMINE AND COMPOSITION CONTAINING ALDIMINE
  申请人：BURCKHARDT Urs

  公开号：US20110253309A1

  公开（公告）日：2011-10-20

  Aldimines of Formula (I), which can be used as latent curing agents in curing compositions, for example, in moisture-curing polyurethane compositions that have isocyanate groups. The aldimines are compounds that can be liquid at room temperature, can have a hardly noticeable aldehyde odor before, during and after hydrolysis, and can have a long shelf life. An aldehyde in polyurethane compositions that is released during hydrolysis has only a slight softening effect and can exhibit very little tendency to migrate or exude.

  式(I)的醛缩胺可以用作固化组合物中的潜在固化剂，例如在具有异氰酸酯基团的湿气固化聚氨酯组合物中。这些醛缩胺化合物可以在室温下为液体，水解前、期间和后几乎没有醛类气味，并且可以具有很长的货架寿命。在水解期间释放的聚氨酯组合物中的醛仅具有轻微的软化效果，并且可以表现出极少的迁移或渗出倾向。
• POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS
  申请人：Butikofer Pierre-Andre

  公开号：US20130261270A1

  公开（公告）日：2013-10-03

  The present invention relates to novel polyamines having secondary amino groups, a process for producing them, adducts of these polyamines and their uses. The polyamines can be prepared in a simple way from readily available reactants. They and their adducts have, in particular, a low viscosity and are suitable as constituent of polyurethane and polyurea compositions having excellent processability and high flexibility, and also constituent of epoxy resin compositions, especially coatings.

  本发明涉及具有次级氨基团的新型多胺，其生产过程，这些多胺的加合物及其用途。这些多胺可以从易得到的反应物中简单制备。它们及其加合物具有低粘度，特别适用于聚氨酯和聚脲组合物的组成部分，具有优异的加工性和高柔韧性，同时也是环氧树脂组合物的组成部分，特别适用于涂料。
• Härtbare Kunstharzmischungen und Mittel für härtbare Kunstharzmischungen auf Basis von präpolymeren Polyätherurethanharnstoffaminen und Epoxidharzen
  申请人：SCHERING AKTIENGESELLSCHAFT

  公开号：EP0084106A1

  公开（公告）日：1983-07-27

  Gegenstand der vorliegenden Erfindung sind härtbare Kunstharzmischungen, bestehend aus einem Polyätherurethanharnstoffamin mit zwei oder mehr reaktiven Aminwasserstoffen pro Molekül, hergestellt durch Umsetzung von di-oder polyfunktionellen Carbamidsäurearylestern mit mindestens einer di- und/oder polyfunktionellen Aminverbindung, welche mindestens zwei reaktive Aminwasserstoffe pro Molekül enthält oder weiche mindestens einen reaktiven Aminwasserstoff und mindestens eine Azomethingruppe pro Molekül enthält, wobei aus den Azomethingruppen enthaltenden Verbindungen durch anschließende Hydrolyse das Amin freigesetzt wird, und Glycidylverbindungen mit im Durchschnitt mehr als einer Epoxidgruppe pro Molekül und gegebenenfalls üblichen Füllstoffen, Pigmenten, Reaktionsbeschleunigern, Viskositätsregulatoren und Additiven.

  本发明涉及可固化的合成树脂混合物，该混合物由每分子含有两个或两个以上反应性胺氢的聚醚氨基甲酸脲胺、二官能团或多官能团氨基甲酸芳基酯与至少一种二官能团和/或多官能团胺化合物反应制备而成，二官能团和/或多官能团胺化合物每分子至少含有两个反应性胺氢，或每分子至少含有一个反应性胺氢和至少一个偶氮甲烷基团，胺通过随后的水解作用从含有偶氮甲烷基团的化合物中释放出来，缩水甘油化合物每分子平均含有一个以上环氧基团，还可选用常规填料、颜料、反应促进剂、粘度调节剂和添加剂。
• Polyamidelastomere, ihre Herstellung und ihre Verwendung
  申请人：BAYER AG

  公开号：EP0423577A1

  公开（公告）日：1991-04-24

  Die Erfindung betrifft amorphe Polyamide mit Elastomer­charakter auf Basis von Dimerfettsäuren und speziellen prim./sek.-Diaminen und/oder speziellen disekundären Di­aminen mit einer Glastemperatur von weniger als + 10°C, die Herstellung dieser amorphen Polyamide und ihre Ver­wendung als Kautschuk, Weichmacher bzw. Schlagzähmodifi­katoren für Thermoplaste, als Weichsegmente zum Aufbau thermoplastischer Elastomerer und für andere Zwecke.

  本发明涉及以二聚体脂肪酸和特殊伯/仲二元胺和/或玻璃化转变温度低于 +10°C 的特殊仲二元胺为基础的具有弹性体特性的无定形聚酰胺、这些无定形聚酰胺的生产及其作为热塑性塑料的橡胶、增塑剂或冲击改性剂、作为热塑性弹性体结构的软段以及其他用途的使用。