phenothiazinyllithium | 4442-10-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: phenothiazinyllithium
• 英文别名: lithium;phenothiazin-10-ide
• CAS: 4442-10-8
• 化学式: C₁₂H₈LiNS
• 分子量: 205.209
• InChiKey: BBYSCIAWFHKCPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.49
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  二甲基溴化硼 、 phenothiazinyllithium 以43.7%的产率得到10-dimethylboranyl-10H-phenothiazine
  参考文献：
  名称：

  Noeth,H.; Wrackmeyer,B., Chemische Berichte, 1973, vol. 106, p. 1145 - 1164

  摘要：

  DOI：

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: B: B-Verb.4, 4.10, page 208 - 214
  作者：

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: B: B-Verb.9, 6.3.2, page 303 - 314
  作者：

  DOI：——

  日期：——
• Reaction of magnesium cyclopropylidene with N-lithio arylamines: a method for generation of α-amino-substituted cyclopropylmagnesiums and a study for their reactivity with electrophiles
  作者：Tsuyoshi Satoh、Mariko Miura、Ken Sakai、Yoshimi Yokoyama

  DOI：10.1016/j.tet.2006.01.080

  日期：2006.4

  Magnesium cyclopropylidene was generated from 1-chlorocyclopropyl phenyl sulfoxide with i-PrMgCl in THF at -78 degrees C in high yield by a sulfoxide-magnesium exchange reaction. The generated magnesium cyclopropylidene was found to be reactive with N-lithio arylamines to give alpha-ammo-substituted cyclopropylmagnesiums. The reaction of the a-amino-substituted cyclopropylmagnesiums with several electrophiles was examined and a new method for a synthesis of cyclopropane amino acid derivatives was realized. (c) 2006 Elsevier Ltd. All rights reserved.
• Direct N- and C-alkenylation of nitrogen-containing heterocycles with magnesium alkylidene carbenoids
  作者：Jo Sakurada、Tsuyoshi Satoh

  DOI：10.1016/j.tet.2007.02.072

  日期：2007.4

  Treatment of magnesium alkylidene carbenoids, which were generated from 1-chlorovinyl p-tolyl sulfoxides with isopropylmagnesium chloride at -78 degrees C in toluene, with N-lithio nitrogen-containing heterocycles gave N-alkenylated products in moderate to good yields. Also, the reaction of C-lithio indoles, which were generated from N-protected indoles, with magnesium alkylidene carbenoids gave C-2 or C-3 alkenylated products, corresponding to the protective group. The intermediate of these reactions were found to be the alkenyl anion, which could be trapped with electrophiles to give the heterocycles having fully substituted alkenes. (C) 2007 Elsevier Ltd. All rights reserved.
• KIM S. H.; MARTIN A. R., J. HETEROCYCL. CHEM., 1978, 15, NO 8, 1503-1504
  作者：KIM S. H.、 MARTIN A. R.

  DOI：——

  日期：——