potassium L-3-phenyllactate | 139232-47-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: potassium L-3-phenyllactate
• 英文别名: (R)-2-hydroxy-3-phenyl-propionic acid ; potassium salt；(R)-2-Hydroxy-3-phenyl-propionsaeure; Kaliumsalz；potassium;(2R)-2-hydroxy-3-phenylpropanoate
• CAS: 139232-47-6
• 化学式: C₉H₉O₃*K
• 分子量: 204.267
• InChiKey: NSTLOTMUJUFASI-DDWIOCJRSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.66
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  60.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-甲基邻苯二甲酰亚胺 、 potassium L-3-phenyllactate 以 水 、 丙酮 为溶剂， 以21%的产率得到3-benzyl-3-hydroxy-2-methyl-2,3-dihydroisoindol-1-one
  参考文献：
  名称：

  Photodecarboxylative benzylations of phthalimides

  摘要：

  Photoadditions of phenylacetates to phthalimides give the corresponding benzylated hydroxyphthalimidines in moderate to high yields of 29-90%. With 2-phenylpropanoate, photoaddition affords a diastereoisomeric mixture in a de of 24% in favour of the like-diastereoisomer. L-3-Phenyl lactate and 2-oxo-3-phenylpropanoate both furnish the benzylated product through subsequent loss of formaldehyde and decarbonylation, respectively. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.08.115

文献信息

• Photodecarboxylative benzylations of phthalimides
  作者：Fadi Hatoum、Sonia Gallagher、Louise Baragwanath、Johann Lex、Michael Oelgemöller

  DOI：10.1016/j.tetlet.2009.08.115

  日期：2009.11

  Photoadditions of phenylacetates to phthalimides give the corresponding benzylated hydroxyphthalimidines in moderate to high yields of 29-90%. With 2-phenylpropanoate, photoaddition affords a diastereoisomeric mixture in a de of 24% in favour of the like-diastereoisomer. L-3-Phenyl lactate and 2-oxo-3-phenylpropanoate both furnish the benzylated product through subsequent loss of formaldehyde and decarbonylation, respectively. (C) 2009 Elsevier Ltd. All rights reserved.