tetrakis(4-morpholinophenyl)ethene

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: tetrakis(4-morpholinophenyl)ethene
• 英文别名: 1,1,2,2-tetra(p-morpholinylphenyl)-ethylene；4-[4-[1,2,2-Tris(4-morpholin-4-ylphenyl)ethenyl]phenyl]morpholine；4-[4-[1,2,2-tris(4-morpholin-4-ylphenyl)ethenyl]phenyl]morpholine
• 化学式: C₄₂H₄₈N₄O₄
• 分子量: 672.868
• InChiKey: FFGBLPXYIPDJEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  50
• 可旋转键数：
  8
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  49.9
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  4,4'-二氯二苯甲酮 在 bis(acetylacetonate)nickel(II) 四氯化钛 、 sodium hydride 、 1,3-双-(2,6-二异丙基苯基)咪唑鎓氯化物 、 锌 、 叔丁醇 作用下， 以 四氢呋喃 、 1,4-二氧六环 为溶剂， 反应 9.0h， 生成 tetrakis(4-morpholinophenyl)ethene
  参考文献：
  名称：

  New tetrakis(4-aminophenyl)ethenes: synthesis and electrochemical investigations

  摘要：

  Four novel functional conjugated tetraarylamines containing a tetraphenylenecore were synthesized via Ni-catalyzed aryl amination followed by McMurry olefination. Their electrochemical properties were studied by cyclic voltammetry, coulometry, and electrolysis monitored by UV-vis spectroscopy, and discussed with regard to those of the known tetrakis(dimethylaminophenyl)ethane. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.10.071

文献信息

• Insights into the General and Efficient Cross McMurry Reactions between Ketones
  作者：Xin-Fang Duan、Jing Zeng、Jia-Wei Lü、Zhan-Bin Zhang

  DOI：10.1021/jo061644d

  日期：2006.12.1

  The selective cross McMurry couplings of diaryl or aryl ketones with various substituted ketones were achieved in 53−94% isolated yields. It is believed that the strong affinity of the substituents to the low-valent titanium surface plays an important role in regards to moderating selectivity. Through the introduction of such substituents followed by their removal post McMurry coupling, structurally

  二芳基或芳基酮与各种取代酮的选择性交叉McMurry偶联以53-94％的分离产率实现。据信，取代基对低价钛表面的强亲和力在缓和选择性方面起着重要作用。通过引入此类取代基，然后在McMurry偶联后将其除去，可以有效地交叉偶联结构相似的酮。
• A Facile Synthesis of Tetraarylethenes via Cross McMurry Coupling between Diaryl Ketones
  作者：Xin-Fang Duan、Jing Zeng、Jia-Wei Lü、Zhan-Bin Zhang

  DOI：10.1055/s-2007-965906

  日期：2007.3

  The one-pot, cross McMurry coupling between two different diaryl ketones gave structurally varied tetraarylethenes in 59-80% isolated yields. This synthetic protocol is more convenient and effective compared to previously reported procedures

  通过两种不同的二芳基酮之间的一锅交叉麦克默里偶联，得到了结构各异的四芳基苯，分离产率为 59-80%。与之前报道的程序相比，该合成方案更加方便有效