2,3-二氢-2-螺-7'-[8'-亚氨基-7',8'-二氢萘-1'-胺]呸啶 | 851768-62-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 2,3-二氢-2-螺-7'-[8'-亚氨基-7',8'-二氢萘-1'-胺]呸啶
• 中文别名: 2,3-二氢-2-螺-7-[8-亚氨基-7,8-二氢萘胺]呸啶
• 英文名称: 2,3-dihydro-2-spiro-7'-[8'-imino-7',8'-dihydronaphthalen-1'-amine]perimidine
• 英文别名: 8'-iminospiro[1,3-dihydroperimidine-2,7'-naphthalene]-1'-amine
• CAS: 851768-62-2
• 化学式: C₂₀H₁₆N₄
• 分子量: 312.374
• InChiKey: CXGACCZEFCWAJN-UHFFFAOYSA-N

物化性质

• 沸点：
  669.3±55.0 °C(Predicted)
• 密度：
  1.41±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  24
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  73.9
• 氢给体数：
  4
• 氢受体数：
  4

安全信息

• 海关编码：
  2933990090

SDS

2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-dihydronaphthalen- Revision number: 5
1'-amine]perimidine
SAFETY DATA SHEET

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Section 1. IDENTIFICATION
Product name: 2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-dihydronaphthalen-1'-amine]perimidine

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Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS Not classified
HEALTH HAZARDS
Skin corrosion/irritation Category 2
Category 2A
Serious eye damage/eye irritation
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Warning
Signal word
Hazard statements Causes skin irritation
Causes serious eye irritation
Precautionary statements:
Wash hands thoroughly after handling.
[Prevention]
Wear protective gloves/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
[Response]
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture: Substance
2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-dihydronaphthalen-1'-amine]perimidine
Components:
Percent: ....
851768-62-2
CAS Number:
Synonyms: 1-Iminospiro[naphthalene-2(1H),2'(3'H)-[1H]perimidin]-8-amine , PNI
Chemical Formula: C20H16N4

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Section 4. FIRST AID MEASURES
Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Inhalation:
Get medical advice/attention if you feel unwell.
2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-
dihydronaphthalen-1'-amine]perimidine

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Section 4. FIRST AID MEASURES
Skin contact: Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
A rescuer should wear personal protective equipment, such as rubber gloves and air-
Protection of first-aiders:
tight goggles.

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Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
from the chemical: generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

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Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a freezer.
Store under inert gas.
Protect from moisture.
Store away from incompatible materials such as oxidizing agents.
Heat-sensitive, Light-sensitive, Moisture-sensitive, Air-sensitive
Packaging material: Comply with laws.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Protective gloves.
Hand protection:
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.
2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-
dihydronaphthalen-1'-amine]perimidine

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Form: Crystal- Powder
Yellow - Reddish yellow
Colour:
Odour: No data available
pH: No data available
Melting point/freezing point:No data available
No data available
Boiling point/range:
Flash point: No data available
Flammability or explosive
limits:
No data available
Lower:
Upper: No data available
Relative density: No data available
Solubility(ies):
No data available
[Water]
[Other solvents] No data available

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Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx)
products:

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Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye No data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC = No data available
No data available
NTP =
Reproductive toxicity: No data available

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.
2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-
dihydronaphthalen-1'-amine]perimidine

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  2,3-二氢-2-螺-7'-[8'-亚氨基-7',8'-二氢萘-1'-胺]呸啶 以 polycarbonate 为溶剂， 生成 7-(8-Aminonaphthalen-1-yl)imino-8-iminonaphthalen-1-amine
  参考文献：
  名称：

  螺哌啶化合物在聚合物基质中的光致变色

  摘要：

  掺杂在各种聚合物中的螺哌啶化合物2,3-二氢-2-螺-7'-（8'-亚氨基-7'，8'-二氢萘-1'-胺）perimidine（PNI）的光致变色行为具有被研究了。在用405 nm光照射时，PNI表现出光致变色现象，并且观察到颜色变化（浅黄色至棕色）。初始（闭合）和有色（打开）的形式表现出的吸收最大值（λ最大）在400和500nm，分别。开放形式具有宽的吸收带，延伸至约750 nm。对聚合物基质的影响不大λ最大观察到的无论是封闭或开放的形式，并且将这些值也相似于那些在溶液中。开放形式的寿命主要取决于玻璃化转变温度（T g），并且其范围为例如11分钟至5.4 d。这表明通过简单地选择合适的聚合物就可以很容易地调节开放形式的寿命。矩阵。本文证明了在不同的聚合物基质中的光致变色。

  DOI：

  10.1039/b822914g
• 作为产物：
  描述：

  7-(8-Aminonaphthalen-1-yl)imino-8-iminonaphthalen-1-amine 以 polycarbonate 为溶剂， 生成 2,3-二氢-2-螺-7'-[8'-亚氨基-7',8'-二氢萘-1'-胺]呸啶
  参考文献：
  名称：

  螺哌啶化合物在聚合物基质中的光致变色

  摘要：

  掺杂在各种聚合物中的螺哌啶化合物2,3-二氢-2-螺-7'-（8'-亚氨基-7'，8'-二氢萘-1'-胺）perimidine（PNI）的光致变色行为具有被研究了。在用405 nm光照射时，PNI表现出光致变色现象，并且观察到颜色变化（浅黄色至棕色）。初始（闭合）和有色（打开）的形式表现出的吸收最大值（λ最大）在400和500nm，分别。开放形式具有宽的吸收带，延伸至约750 nm。对聚合物基质的影响不大λ最大观察到的无论是封闭或开放的形式，并且将这些值也相似于那些在溶液中。开放形式的寿命主要取决于玻璃化转变温度（T g），并且其范围为例如11分钟至5.4 d。这表明通过简单地选择合适的聚合物就可以很容易地调节开放形式的寿命。矩阵。本文证明了在不同的聚合物基质中的光致变色。

  DOI：

  10.1039/b822914g

文献信息

• Modulation of Unconventional Fluorescence of Novel Photochromic Perimidine Spirodimers
  作者：Riju Davis、Nobuyuki Tamaoki

  DOI：10.1002/chem.200600190

  日期：2007.1.2

  Fluorescence modulation by a class of photochromic perimidine spirodimers, which exhibit a characteristic fluorescence associated with their photochromic reactions, has been described. Upon irradiation using 365 nm light, these non-fluorescent spiro molecules undergo a thermally-reversible ring opening at their spiro junction resulting in the generation of strong fluorescence. The fluorescing species

  已经描述了由一类光致变色perimidine spirodimers进行的荧光调节，其表现出与其光致变色反应相关的特征性荧光。在使用365 nm光照射后，这些非荧光螺分子在其螺结处经历了热可逆的开环，从而产生了强荧光。荧光物质与稳定的闭环化合物和开环化合物都明显不同，尽管它似乎是由光化学生成的开环形式形成并保持平衡。虽然发荧光物质具有一条狭窄的吸收带，其最大吸收中心位于500 nm，但开环形式在可见光区域显示出较宽的吸收率，其中两个最大值分别位于410和650 nm。在使用365 nm光在这些分子中引发光致变色反应后，可以使用可见光区域中的两个波长（即500和700 nm）进行纯光化学控制的荧光调制，同时开环形式的平衡浓度为荧光物质受到控制。通过通过光化学开环和热闭环反应控制闭环和开环形式的比例也可以实现荧光调节。关于这些分子的取代作用的研究表明，通过扩展开环形式的嘧啶核的缀合，该分子成为
• Novel Photochromic Spiroheterocyclic Molecules via Oxidation of 1,8-Diaminonaphthalene
  作者：Riju Davis、Nobuyuki Tamaoki

  DOI：10.1021/ol050138s

  日期：2005.4.14

  [GRAPHICS]Novel spiroheterocyclic molecules, namely, 2,3-dihydro-2-spiro-7'-[8'-imino-7',8'-dihydronaphthalen-1'-amine]perimidine, PNI, and 2,3-dihydro2-spiro-4'-[8'-aminonaphthalen-1'(4H)-one]perimidine, PNO-p, were obtained by oxidation of 1,8-diaminonaphthalene using manganese dioxide. These molecules exhibit thermally reversible photochromism with good photofatigue resistance, and their photogenerated forms possess broad absorption in the visible region.
• COLOR TONE VARIABLE FILM, METHOD OF MANUFACTURING THE SAME, AND ELECTROCHROMIC ELEMENT OBTAINED BY THE MANUFACTURING METHOD
  申请人：INAGAKI Yoshio

  公开号：US20110242637A1

  公开（公告）日：2011-10-06

  The present invention provides a color tone variable film which is formed by a reaction of a cationic polymer containing a structural unit containing a positive ionic group in a side chain and a compound containing an acid group and a partial structure which can change color tone as a result of energy application, which can be formed by a wet method, which has flexibility and strength in practical use, and which changes color tone with high sensitivity as a result of energy application, a simple manufacturing method thereof, and an electrochromic element obtained by the manufacturing method.
• PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES
  申请人：Meyering Emily R. Rolfes

  公开号：US20120082713A1

  公开（公告）日：2012-04-05

  The invention provides polymers comprising pendent photochrome or near IR dye groups, as well as polymeric matrices made from these polymers, which can be used as or in association with a medical article. The polymers can be synthesized using methods that facilitate the preparation of medical articles having good biocompatibility. Exemplary polymeric matrices are in the form of lubricious coatings on medical devices, such as catheters. Visualization by irradiation of the photochrome or near IR dye can improve detection of the polymeric matrix on a device or in the body. This, in turn can improve aspects of a medical procedure, such as device insertion or matrix formation, as well as being useful for assessing the quality of the matrix.
• PHOTOCHROMIC DETECTION OF ULTRAVIOLET IRRADIATION
  申请人：PurpleSun Inc.

  公开号：US20150343102A1

  公开（公告）日：2015-12-03

  The present invention provides methods for detecting electromagnetic energy (e.g., ultraviolet radiation) and articles suitable for use in such methods. The methods and articles can be useful for detecting sterilization or disinfection resulting from electromagnetic energy such as ultraviolet C. Detection of the sterilization or disinfection allows discontinuation of the exposure when a desired level of sterilization or disinfection has been obtained. Feedback mechanisms for controlling exposure to the energy may also be used.