(3,7-dimethyl-[1]naphthyl)-methyl ether

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (3,7-dimethyl-[1]naphthyl)-methyl ether
• 英文别名: (3,7-Dimethyl-[1]naphthyl)-methyl-aether；4-Methoxy-2.6-dimethyl-naphthalin；1-Methoxy-3,7-dimethylnaphthalene
• 化学式: C₁₃H₁₄O
• 分子量: 186.254
• InChiKey: CWXXYFJAXRAIFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (3,7-dimethyl-[1]naphthyl)-methyl ether 在 sodium hydroxide 、 三氯化铝 、 硝基苯 、 锌 作用下， 生成 2-(4-methoxy-2,6-dimethyl-[1]naphthylmethyl)-benzoic acid
  参考文献：
  名称：

  Some Further Derivatives of Pleiadene¹

  摘要：

  DOI：

  10.1021/ja01339a043
• 作为产物：
  描述：

  1-Hydroxy-3,7-dimethylnaphthalene 、 硫酸二甲酯 在 sodium hydroxide 作用下， 生成 (3,7-dimethyl-[1]naphthyl)-methyl ether
  参考文献：
  名称：

  Some Further Derivatives of Pleiadene¹

  摘要：

  DOI：

  10.1021/ja01339a043

文献信息

• Liquid crystal compound, liquid crystal composition and liquid crystal display device
  申请人：JNC CORPORATION

  公开号：US10208249B2

  公开（公告）日：2019-02-19

  Provided are a liquid crystal compound satisfying at least one of physical properties such as high stability to heat or light, high maximum temperature of a liquid-crystal phase, low minimum temperature thereof, small viscosity, suitable optical anisotropy, large dielectric anisotropy and good compatibility with other liquid-crystal compounds, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A compound is represented by formula (1), a liquid crystal composition contains the compound and a liquid crystal display device includes the composition. In formula (1), Ra and Rb are fluorine or alkyl; A0, A1 and A2 are 1,4-phenylene; Z1 and Z2 are a single bond or alkylene; one of Y1 and Y2 is fluorine, and the other is hydrogen; Rc is alkyl; and a and b are independently 0, 1, 2 or 3, and a sum of a and b is 0, 1, 2 or 3.

  本发明提供了一种液晶化合物，该化合物至少满足以下物理特性之一：对热或光的稳定性高、液晶相的最高温度高、最低温度低、粘度小、光学各向异性合适、介电各向异性大以及与其他液晶化合物的兼容性好；一种含有该化合物的液晶组合物和一种包括该组合物的液晶显示设备。 一种化合物用式（1）表示，一种液晶组合物包含该化合物，一种液晶显示设备包含该组合物。 在式 (1) 中，Ra 和 Rb 是氟或烷基；A0、A1 和 A2 是 1,4-亚苯基；Z1 和 Z2 是单键或亚烷基；Y1 和 Y2 中的一个是氟，另一个是氢；Rc 是烷基；a 和 b 独立地为 0、1、2 或 3，a 和 b 之和为 0、1、2 或 3。
• LIQUID CRYSTAL COMPOSITION AND RETARDATION FILM
  申请人：Takeuchi Hiroshi

  公开号：US20100078593A1

  公开（公告）日：2010-04-01

  The invention relates to a liquid crystal composition comprising two or more species of liquid crystal compounds respectively having a polymerizable group, at least one species of which being a compound represented by formula (I) below, having a content of the compound of from 20% to 80% relative to the total mass of said two or more species of liquid crystal compounds. In formula (I), P 1 represents a polymerizable group; each of L 1 and L 2 represents a divalent spacer group; each of Z 1 to Z 4 represents a divalent linking group; each of A 1 and A 2 represents a divalent cyclic group; each of m and n represents an integer from 0 to 3; MA represents any one group of A-I to A-V below:
• LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20180086979A1

  公开（公告）日：2018-03-29

  Provided are a liquid crystal compound satisfying at least one of physical properties such as high stability to heat or light, high maximum temperature of a liquid-crystal phase, low minimum temperature thereof, small viscosity, suitable optical anisotropy, large dielectric anisotropy and good compatibility with other liquid-crystal compounds, a liquid crystal composition containing the compound and a liquid crystal display device including the composition. A compound is represented by formula (1), a liquid crystal composition contains the compound and a liquid crystal display device includes the composition. In formula (1), Ra and Rb are fluorine or alkyl; A 0 , A 1 and A 2 are 1,4-phenylene; Z 1 and Z 2 are a single bond or alkylene; one of Y 1 and Y 2 is fluorine, and the other is hydrogen; Rc is alkyl; and a and b are independently 0, 1, 2 or 3, and a sum of a and b is 0, 1, 2 or 3.
• US8568839B2
  申请人：——

  公开号：US8568839B2

  公开（公告）日：2013-10-29
• [EN] ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF<br/>[FR] ANALOGUES DE L'ISOXAZOLE UTILISÉS EN TANT QU'AGONISTES DE FXR ET LEURS PROCÉDÉS D'UTILISATION
  申请人：ENANTA PHARM INC

  公开号：WO2019118571A1

  公开（公告）日：2019-06-20

  The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediated diseases or conditions.