N-(sec-butyl)hexan-1-amine | 20007-05-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(sec-butyl)hexan-1-amine
• 英文别名: N-sec.-Butyl-hexylamin；Sec-butyl-n-heptyl-amine；N-butan-2-ylhexan-1-amine
• CAS: 20007-05-0
• 化学式: C₁₀H₂₃N
• mdl: MFCD11161725
• 分子量: 157.299
• InChiKey: RKZDBZGVXRBMGQ-UHFFFAOYSA-N

物化性质

• 沸点：
  74-75 °C
• 密度：
  0.775±0.06 g/cm3(Predicted)
• 保留指数：
  1189

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  正己胺 在 potassium fluoride 、 aluminium amalgam 作用下， 生成 N-(sec-butyl)hexan-1-amine
  参考文献：
  名称：

  The Reduction of Schiff Bases with Aluminum Amalgam

  摘要：

  DOI：

  10.1246/bcsj.41.506

文献信息

• Ruthenium catalyzed synthesis of secondary or tertiary amines from amines and alcohols
  作者：Shun-Ichi Murahashi、Kaoru Kondo、Toshiyuki Hakata

  DOI：10.1016/s0040-4039(00)86792-1

  日期：1982.1

  Unsymmetrical secondary and tertiary amines are prepared by the ruthenium catalyzed reaction of alcohols with amines, which provides highly efficient method for synthesis of cyclic amines.

  不对称仲胺和叔胺是通过醇与胺的钌催化反应制备的，这为合成环状胺提供了高效的方法。
• Facile Synthesis and Isolation of Secondary Amines <i>via</i> a Sequential Titanium(IV)-Catalyzed Hydroamination and Palladium-Catalyzed Hydrogenation
  作者：Erica K. J. Lui、Laurel L. Schafer

  DOI：10.1002/adsc.201500861

  日期：2016.3.3

  alkyl‐substituted secondary amines has been developed. Using a bis(amidate)bis(amido)titanium(IV) precatalyst, the hydroamination of terminal alkynes with a range of amines results in the selective formation of the anti‐Markovnikov product. The crude enamine/imine mixtures are effectively hydrogenated using palladium on carbon (Pd/C) and H2 to afford the corresponding secondary amine in excellent yields.

  已开发出一种原子经济且催化的路线，用于合成芳基和烷基取代的仲胺。使用双（酰胺基）双（酰胺基）钛（IV）预催化剂，末端炔烃与一系列胺进行加氢胺化，选择性地形成了反马尔科夫尼科夫产物。使用碳载钯（Pd / C）和H 2有效地氢化粗制的烯胺/亚胺混合物，从而以优异的收率得到相应的仲胺。简单的后处理程序可以分离纯化合物，同时避免通过柱色谱法纯化。
• Design of a Bifunctional Ir-Zr Based Metal-Organic Framework Heterogeneous Catalyst for the N-Alkylation of Amines with Alcohols
  作者：A. M. Rasero-Almansa、A. Corma、M. Iglesias、F. Sánchez

  DOI：10.1002/cctc.201402101

  日期：2014.6

  The direct N‐alkylation of amines with alcohols was performed with an Ir‐Zr‐based metal–organic framework multifunctional heterogeneous catalyst. This system is efficient and environmentally benign for the synthesis of various organic amines in air in the absence of a base. The catalyst was recovered and reused without significant loss of activity, and only water was produced as a byproduct.

  胺与醇的直接N-烷基化反应是基于Ir-Zr基金属-有机骨架多功能非均相催化剂进行的。该系统对于在不存在碱的情况下在空气中合成各种有机胺是有效且对环境无害的。回收催化剂并重新使用，而活性没有明显损失，仅产生水作为副产物。
• Aqueous ink composition for use in an ink-jet printer
  申请人：SEIKO EPSON CORPORATION

  公开号：EP0838508A2

  公开（公告）日：1998-04-29

  An aqueous ink composition for ink jet printers, which gives reliable printing performance and yields printed images which have excellent print quality and which dry rapidly is disclosed. The ink compositions are suitable for printing on plain paper. The ink comprises water as the principal solvent, an anionic colorant, pectic acid, a base, and at least one of a penetrable solvent and/or a penetrability-imparting surfactant. The pectic acid is composed primarily of α-1,4 linked polygalacturonic acid having a degree of esterification not more than 5% where the degree of esterification is defined as the percentage of the total number of galacturonic acid units in the pectic acid which are esterified.

  本发明公开了一种用于喷墨打印机的水性油墨组合物，该组合物具有可靠的打印性能，可打印出打印质量极佳且干燥迅速的图像。这种油墨组合物适用于在普通纸上打印。油墨包括作为主溶剂的水、阴离子着色剂、果胶酸、碱和至少一种可渗透溶剂和/或渗透性促进表面活性剂。果胶酸主要由α-1,4 连接的聚半乳糖醛酸组成，其酯化程度不超过 5%，其中酯化程度定义为果胶酸中酯化的半乳糖醛酸单位总数的百分比。
• Endovascular impant
  申请人：Intact Vascular, Inc.

  公开号：US10278839B2

  公开（公告）日：2019-05-07

  A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.

  斑块粘扣带可用于将斑块固定在血管壁上，例如用于治疗动脉粥样硬化性闭塞疾病。斑块粘扣带可以形成环形薄带，用于在弹簧或其他膨胀力的作用下将松动的斑块固定在血管壁上。病灶提升元件和/或其他特征（如锚）可用于对斑块位置施加保持力，同时最大限度地减少与斑块或血管壁接触的材料表面积，降低与内腔表面摩擦的可能性。这种方法使临床医生能够在血管成形术后进行微创治疗，并在不使用支架的情况下获得类似支架的效果。