4-O-hydroxyethyldihydrocoumaric acid | 51822-73-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 4-O-hydroxyethyldihydrocoumaric acid
• 英文别名: 4-(2-hydroxyethoxy)phenylpropanoic acid；3-[4-(2-hydroxy-ethoxy)-phenyl]-propionic acid；3-[4-(2-Hydroxy-aethoxy)-phenyl]-propionsaeure；3-[4-(2-Hydroxyethoxy)phenyl]propanoic acid
• CAS: 51822-73-2
• 化学式: C₁₁H₁₄O₄
• 分子量: 210.23
• InChiKey: JEGPZOMBZCEYFS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-O-hydroxyethyldihydrocoumaric acid 在 五氯化磷 、 苯 作用下， 生成 3-[4-(2-氯-乙氧基)-苯基]-丙酸
  参考文献：
  名称：

  The localization of type 2 diabetes susceptibility gene loci in northern Chinese Han families

  摘要：

  We conducted a genome-wide scan, in which 358 well distributed fluorescent dye-labeled microsatellite marker sets were applied in 32 Chinese Han type 2 diabetes families from Northern China to search for the susceptibility gene loci. The data collected from screening all the chromosomes of genome were genotyped by using genescan and genotyping software, then, parametric and non-parametric multipoint test, and affected sib-pair analysis as well, were used to analyze the data. We identified some susceptibility gene loci residing in chromosomes 1,12,18,20, respectively, or precisely, located around D1S214, D1S207, D1S218, D1S235, D12S336, D18S61 and D20S118. The comparison of this result with those from other regions and races reflected the complexity and heterogeneity of type 2 diabetes.

  DOI：

  10.1007/bf02886269
• 作为产物：
  描述：

  (2E)-3-[4-(2-羟基乙氧基)苯基]丙烯酸 在 乙醇 、 镍 作用下， 生成 4-O-hydroxyethyldihydrocoumaric acid
  参考文献：
  名称：

  The localization of type 2 diabetes susceptibility gene loci in northern Chinese Han families

  摘要：

  We conducted a genome-wide scan, in which 358 well distributed fluorescent dye-labeled microsatellite marker sets were applied in 32 Chinese Han type 2 diabetes families from Northern China to search for the susceptibility gene loci. The data collected from screening all the chromosomes of genome were genotyped by using genescan and genotyping software, then, parametric and non-parametric multipoint test, and affected sib-pair analysis as well, were used to analyze the data. We identified some susceptibility gene loci residing in chromosomes 1,12,18,20, respectively, or precisely, located around D1S214, D1S207, D1S218, D1S235, D12S336, D18S61 and D20S118. The comparison of this result with those from other regions and races reflected the complexity and heterogeneity of type 2 diabetes.

  DOI：

  10.1007/bf02886269

文献信息

• Semi-aromatic biobased polyesters derived from lignin and cyclic carbonates
  作者：DeMichael Winfield、John Ring、Jessica Horn、Evan M. White、Jason Locklin

  DOI：10.1039/d1gc03135j

  日期：——

  The synthesis of biobased aromatic polyesters from lignin-derived monomers has become well described in the literature, but robust extrusion, thermomechanical, tensile and degradation studies of these materials is lacking. In this work, we have systematically investigated the mechanical and biodegradation properties of semi-aromatic polyesters that can potentially be derived from lignin. AB monomers

  从木质素衍生单体合成生物基芳香族聚酯已在文献中得到很好的描述，但缺乏对这些材料的稳健挤出、热机械、拉伸和降解研究。在这项工作中，我们系统地研究了可能源自木质素的半芳香族聚酯的机械和生物降解性能。AB 单体由香豆酸、阿魏酸和芥子酸的还原类似物以及环状碳酸酯合成，其中使用 E-Factor 和 EcoScale 评估合成方法。聚合产生了机械性能在三个数量级上变化的半结晶和无定形聚酯。详细的表征揭示了广泛的特性，包括高延展性的热塑性塑料、一种强而硬的热塑性塑料和一种弹性体。堆肥生物降解测试表明，可降解和不可降解聚合物都可以在此类中实现。这项工作证明了此类聚合物的多功能性，并说明了它们替代非可持续衍生塑料的潜力。
• Polyethylene ferulate (PEF) and congeners: polystyrene mimics derived from biorenewable aromatics
  作者：Ha Thi Hoang Nguyen、Marcus H. Reis、Pengxu Qi、Stephen A. Miller

  DOI：10.1039/c5gc01104c

  日期：——

  Ferulic acid and coumaric acid are abundantly available bioaromatics from megacrop agricultural waste (such as sugarcane bagasse) and are functional building blocks for polystyrene mimics.

  香豆酸和香草酸是从大型农作物废弃物（如甘蔗渣）中丰富可得的生物芳香化合物，是聚苯乙烯模拟物的功能性构建块。