6-hydroxy-1,2,3-benzothiadiazole | 7686-32-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻二唑类
• 英文名称: 6-hydroxy-1,2,3-benzothiadiazole
• 英文别名: benzo[1,2,3]thiadiazol-6-ol；6-hydroxybenzo-1,2,3-thiadiazole；6-Hydroxy-1,2,3-benzothiadiazol；6-Hydroxy-benzothiadiazol；Benzo[d][1,2,3]thiadiazol-6-ol；1,2,3-benzothiadiazol-6-ol
• CAS: 7686-32-0
• 化学式: C₆H₄N₂OS
• 分子量: 152.177
• InChiKey: LVZGMLBCOKELEL-UHFFFAOYSA-N

物化性质

• 熔点：
  211-213 °C
• 沸点：
  307.7±34.0 °C(Predicted)
• 密度：
  1.554±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  6-hydroxy-1,2,3-benzothiadiazole 、 硫酸二甲酯 在 sodium hydroxide 作用下， 生成 6-甲氧基苯并[D][1,2,3]噻二唑
  参考文献：
  名称：

  183. 1,2,3-苯并噻二唑。第三部分 5-和7-氨基1,2,3-苯并噻二唑的亲电取代反应和一些取代的1,2,3-苯并噻二唑的制备

  摘要：

  DOI：

  10.1039/jr9650001023
• 作为产物：
  描述：

  6-氯-7-硝基-1,2,3-苯并噻二唑 在 盐酸 、 tetrafluoroboric acid 、 sodium ethanolate 、 tin(ll) chloride 、 sodium nitrite 作用下， 以 盐酸 、 异丙醇 为溶剂， 反应 7.25h， 生成 6-hydroxy-1,2,3-benzothiadiazole
  参考文献：
  名称：

  Lenic, M.; Merslavic, M.; Polanc, S., Journal of Heterocyclic Chemistry, 1980, vol. 17, p. 1441 - 1445

  摘要：

  DOI：

文献信息

• [EN] HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS MODIFICATEURS D'HÉMOGLOBINE ET LEURS UTILISATIONS
  申请人：FRONTHERA U S PHARMACEUTICALS LLC

  公开号：WO2017218960A1

  公开（公告）日：2017-12-21

  Described herein are compounds, including pharmaceutically acceptable salts thereof, methods of making such compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat, prevent or diagnose blood-based diseases, disorders or conditions.

  本文描述了化合物，包括其药用可接受的盐，制备这些化合物的方法，包含这些化合物的药物组合物，以及使用这些化合物治疗、预防或诊断基于血液的疾病、紊乱或状况的方法。
• 1,2,3-Benzothiadiazoles. Part III. Nucleophilic substitution reactions in halogeno-1,2,3-benzothiadiazoles
  作者：J. H. Davies、E. Haddock、P. Kirby、Shirley B. Webb

  DOI：10.1039/j39710002843

  日期：——

  Nucleophilic substitution reactions have been carried out on a variety of mono- and di-halogeno-1,2,3-benzothiadiazoles. The products isolated vary with the nature of the nucleophile and also with both the halogen itself and its position of substitution on the ring.

  亲核取代反应已经在多种单-和二-卤代-1,2,3-苯并噻二唑上进行了。所分离的产物随亲核试剂的性质以及卤素本身及其在环上的取代位置而变化。
• Herbicidal compositions and method of safening herbicides using benzothiazole derivatives
  申请人：American Cyanamid Company

  公开号：EP1021953A1

  公开（公告）日：2000-07-26

  The invention relates to methods for protecting cereal crops from injury caused by a herbicidally effective amount of a herbicide, in particular, herbicides selected from the group consisting of AHAS-inhibiting, ACCase-inhibiting and HPPD-inhibiting herbicides, which comprises applying to the crop plant, the seed of the crop, or the soil surrounding the crop or crop seed an effective non-phytotoxic antidotal amount of a benzothiazole derivative of formula I wherein A represents an alkyl, alkoxy, haloalkoxy, hydroxy, cyano or nitro group or a group of the formula in which W represents O or S, and R represents a hydroxy, thiol, alkoxy, thioalkyl, amino, alkylamino or dialkylamino group; and X represents CH or N; Also included are safened herbicidal compositions comprising a herbicidally effective amount of a herbicide and an effective nonphytotoxic antidotal amount a benzothiazole derivative of formula I.

  本发明涉及保护谷类作物免受除草有效量除草剂伤害的方法，特别是从AHAS抑制型、ACCase抑制型和HPPD抑制型除草剂组成的组中选出的除草剂，其中包括向作物植株、作物种子或作物或作物种子周围的土壤施用有效的非植物毒性的式I苯并噻唑衍生物的解毒剂量 其中 A 代表烷基、烷氧基、卤代烷氧基、羟基、氰基或硝基或式中的基团 其中 W 代表 O 或 S，R 代表羟基、硫醇基、烷氧基、硫代烷基、氨基、烷基氨基或二烷基氨基；以及 X 代表 CH 或 N； 还包括安全除草组合物，该组合物包含除草有效量的除草剂和有效的非植物毒性抗毒量的式 I 苯并噻唑衍生物。
• Method for protecting crops from parasitic weeds using benzothiazole derivatives
  申请人：KOGEL, KARL-HEINZ, Prof., Dr.

  公开号：EP1243178A1

  公开（公告）日：2002-09-25

  The invention relates to method for protecting crops from injury and infestation caused by a parasitic weed which comprises applying an effective non-phytotoxic amount of a benzothiazole derivative of formula I in which A is defined in the specification and X represents CH or N; to the crop plant, the seed of the crop, or the soil surrounding the crop or crop seed.

  本发明涉及保护农作物免受寄生杂草伤害和侵扰的方法，该方法包括施用无植物毒性的有效量的式 I 苯并噻唑衍生物。 其中 A在说明书中定义 X 代表 CH 或 N； 对作物植株、作物种子或作物或作物种子周围的土壤施用。
• METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM
  申请人：Toyo Ink Mfg. Co., Ltd

  公开号：EP1952918A1

  公开（公告）日：2008-08-06

  Disclosed is a method for producing a metal particle dispersion wherein a metal compound is reduced by using carbodihydrazide represented by the formula (1) below or a polybasic acid polyhydrazide represented by the formula (2) below (wherein R represents an n-valent polybasic acid residue) in a liquid medium. By reducing the metal compound in the presence of a compound having a function preventing discoloration of the metal, there can be obtained a metal particle dispersion having excellent discoloration preventing properties. Metal particles produced by such methods have a uniform particle diameter and are excellent in dispersion stability. By using a conductive resin composition or conductive ink containing a metal particle dispersion obtained by such production methods, there can be formed a conductive coating film, such as a conductive circuit or an electromagnetic layer, having good characteristics.

  本发明公开了一种生产金属颗粒分散液的方法，该方法通过在液体介质中使用下式 (1) 所代表的碳二酰肼或下式 (2) 所代表的多基酸多酰肼（其中 R 代表正价多基酸残基）还原金属化合物。通过在具有防止金属褪色功能的化合物存在下还原金属化合物，可获得具有优异防褪色性能的金属颗粒分散液。通过这种方法制得的金属颗粒具有均匀的颗粒直径和出色的分散稳定性。使用含有通过这种生产方法获得的金属颗粒分散体的导电树脂组合物或导电墨水，可以形成具有良好特性的导电涂膜，例如导电电路或电磁层。