N,N-dihexadecylphenylamine | 77772-74-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-dihexadecylphenylamine
• 英文别名: N,N-dihexadecylaniline；N,N-dihexadecyl-aniline；N,N-Dihexadecyl-anilin；Di-n-hexadecyl-anilin；Dicetylanilin
• CAS: 77772-74-8
• 化学式: C₃₈H₇₁N
• 分子量: 541.988
• InChiKey: IEVJIMWHPIWBIS-UHFFFAOYSA-N

物化性质

• 熔点：
  24 °C
• 沸点：
  610.2±24.0 °C(Predicted)
• 密度：
  0.870±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  17.5
• 重原子数：
  39
• 可旋转键数：
  31
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-dihexadecylphenylamine 在 氢氧化钾 、 三氯氧磷 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 42.0h， 生成 4-N,N-dihexadecylamino-4'-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}chalcone
  参考文献：
  名称：

  Micelles of Lipid−Oligonucleotide Conjugates:  Implications for Membrane Anchoring and Base Pairing

  摘要：

  This report examines the organization properties of new fluorescent DNA-lipids, either alone in water or in interaction with 1-otyl-beta-D-glucopyranoside micelles or egg phosphatidylcholine vesicles. We first describe the design and the syntheses of the conjugates. Then, we use UV-Vis absorption, steady-state fluorescence emission, electron microscopy, and fluorescence correlation spectroscopy after two-photon excitation to show that these DNA-lipids form spherical micelles in aqueous solution and incorporate much better in micelles than in vesicles. We also investigate the significance of the lipophilic chains of these DNA-lipids on the melting behavior of the double-stranded hybrids: in water melting curves are broadened whereas in amphiphilic assemblies duplexes melt as the unconjugated controls. This work is expected to be useful for improving the rational design of antisense medicines.

  DOI：

  10.1021/jp031188m
• 作为产物：
  描述：

  碘十六烷 生成 N,N-dihexadecylphenylamine
  参考文献：
  名称：

  Fridau, Justus Liebigs Annalen der Chemie, 1852, vol. 83, p. 15

  摘要：

  DOI：

文献信息

• The investigation of second harmonic generation from novel molecules [(E)-N-alkyl-4-{2-[4-(dialkylamino)phenyl]ethenyl}pyridazinium iodide]
  作者：T-r. Cheng、C-h. Huang、L-b. Gan、C-p. Luo、A.-c. Yu、X-s. Zhao

  DOI：10.1039/a707724f

  日期：——

  (E)-N-Methyl-4-2-[4-(dihexadecylamino)phenyl]ethenyl}pyridazinium iodide (MHPd), (E)-N-octadecyl-4-2-[4-(dimethylamino)phenyl]ethenyl}pyridazinium iodide (OMPd), (E)-N-octadecyl-4-2-[4-(diethylamino)phenyl]ethenyl}pyridazinium iodide (OEPd), (E)-N-octadecyl-4-2-[4-(dibutylamino)phenyl]ethenyl}pyridazinium iodide (OBPd) have been designed and synthesized. Their Langmuir–Blodgett film forming properties and second harmonic generation were studied. According to the results observed, MHPd is the best among the four congeners. By comparing the NLO properties of OMPd with those of a known compound, OMPy [(E)-N-octadecyl-4-2-[4-(dimethylamino)phenyl]ethenyl}pyridinium iodide], the impairing effect of the second nitrogen in the six-membered pyridazine ring was examined experimentally and theoretically.

  (E)-N-甲基-4-2-[4-(二十六烷基氨基)苯基]乙烯基}碘化哒嗪鎓 (MHPd), (E)-N-十八烷基-4-2-[4-(二甲基氨基)苯基]乙烯基}碘化哒嗪 (OMPd)、(E)-N-十八烷基-4-2-[4-(二乙氨基)苯基]乙烯基}碘化哒嗪 (OEPd)、(E)-N-十八烷基-4-2-设计并合成了[4-(二丁基氨基)苯基]乙烯基}碘化哒嗪鎓(OBPd)。研究了它们的 Langmuir-Blodgett 成膜特性和二次谐波的产生。根据观察结果，MHPd是四种同类物中最好的。通过将OMPd的NLO性质与已知化合物OMPy [(E)-N-十八烷基-4-2-[4-(二甲基氨基)苯基]乙烯基}碘化吡啶]进行比较，发现第二个氮的削弱作用对六元哒嗪环的结构进行了实验和理论研究。
• An investigation on the two-photon absorption activity of various terpyridines and related homoleptic and heteroleptic cationic Zn(ii) complexes
  作者：Stefania Righetto、Sergio Rondena、Danika Locatelli、Dominique Roberto、Francesca Tessore、Renato Ugo、Silvio Quici、Silvia Roma、Dmitry Korystov、Vojislav I. Srdanov

  DOI：10.1039/b515129e

  日期：——

  The two-photon absorption (TPA) properties of various terpyridines of the kind [4′-(C6H4-p-X)-2,2′∶6′,2″-terpyridine] and related homoleptic and heteroleptic bis(terpyridine) cationic zinc(II) complexes were investigated by the TPA induced photoluminescence (TPA-PL) method in a femtosecond regime. It appeared that terpyridines bearing an X donor group are characterized by TPA cross sections among the largest ever reported for a molecule with a dipole symmetry whereas coordination to a Zn(II) center leads to a decrease of the TPA response.

  在飞秒范围内，通过TPA诱导光致发光（TPA-PL）方法研究了各种[4′-(C6H4-p-X)-2,2′∶6′,2″-三联吡啶]类三联吡啶以及相关的同价和异价双（三联吡啶）阳离子锌（II）复合物的双光子吸收（TPA）特性。 结果表明，带有X供体基团的三联吡啶具有迄今为止报道的最大偶极对称分子TPA截面，而与Zn（II）中心的配位则导致TPA响应降低。
• Particle with luminescer for assays
  申请人：Syntex (U.S.A.) Inc.

  公开号：US04891324A1

  公开（公告）日：1990-01-02

  Assay methods are provided for determining an analyte in a sample suspected of containing the analyte. The method is carried out using a composition that includes a conjugate of a first sbp member with a particle. A luminescer is reversibly associated with a nonaqueous phase of the particle. Where the first sbp member is not complementary to the analyte, a second sbp member that is capable of binding to the first sbp member is employed. Unbound conjugate is separated from conjugate that is bound to the analyte or to the second sbp member. A reagent for enhancing the detectability of the luminescer is added and the light emission of the luminescer acted on by the reagent is measured.

  提供了一种测定样品中可能含有的分析物的测定方法。该方法使用包括第一种与粒子结合的sbp成员的共轭物的组合物进行。发光体可逆地与粒子的非水相相关联。如果第一种sbp成员与分析物不互补，则使用能够结合到第一种sbp成员的第二种sbp成员。未结合的共轭物与结合到分析物或第二种sbp成员的共轭物分离。添加增强发光体可检测性的试剂，并测量试剂作用下发光体的光发射。
• CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING THE CATALYST COMPOSITION
  申请人：Yabukami Minoru

  公开号：US20130102745A1

  公开（公告）日：2013-04-25

  The present invention provides a catalyst composition and a method for producing an olefin polymer using the catalyst composition. The catalyst composition is prepared by bringing (A) a transition metal compound, (B) a solid boron compound capable of forming an ion pair with the component (A), (C) an organometallic compound and (D) a compound represented by the following general formula (XIV) and/or the following general formula (XV) into contact with each other in a hydrocarbon solvent, and enables a high catalyst concentration. Z 5 R 14 R 15 (XIV) Z 6 R 14 R 15 R 16 (XV) [In the formulae, Z 5 represents an oxygen atom, etc.; Z 6 represents a nitrogen atom, etc.; R 14 to R 16 each independently represent an organic group, and at least one of those organic groups is an organic group having at least 3 carbon atoms, and R 14 to R 16 may bond to each other to form a ring.]

  本发明提供了一种催化剂组合物及使用该催化剂组合物生产烯烃聚合物的方法。该催化剂组合物是通过将（A）过渡金属化合物，（B）固体硼化合物与组分（A）形成离子对的固体硼化合物，（C）有机金属化合物和（D）由下列一般式（XIV）和/或下列一般式（XV）所表示的化合物在烃溶剂中接触而制备的，并能够实现高催化剂浓度。 Z5R14R15（XIV） Z6R14R15R16（XV） [在公式中，Z5代表氧原子等；Z6代表氮原子等；R14到R16各自独立地代表有机基团，其中至少有一个有机基团是具有至少3个碳原子的有机基团，且R14到R16可以相互结合形成环。]
• Particle separation method
  申请人：SYNTEX (U.S.A.) INC.

  公开号：EP0230768A1

  公开（公告）日：1987-08-05

  A method is disclosed for separating a substance from a liquid medium. The method comprises combining the liquid medium containing the substance with magnetic particles under conditions for non-specific chemical binding of the magnetic particles. Thereafter, the medium is subjected to a magnetic field gradient to separate the particles from the medium. The preferred non-specific binding is achieved as the result of charge interactions between the particles usually by means of a polyionic reagent. The method of the invention has particular application to the separation of cells and microorganisms from aqueous suspensions and also to the determination of an analyte in a sample suspected of containing the analyte. The analyte is a member of a specific binding pair (sbp). The sample is combined in an assay medium with magnetic particles and a sbp member complementary to the analyte. Magnetic or non-magnetic particles capable of specific binding to the analyte or its complementary sbp member must be included in the assay medium. The combination is made under conditions for non-specifically aggregating the magnetic particles or coaggregating the magnetic and non-magnetic particles when non-magnetic particles are present. The assay medium is subjected to a magnetic field gradient to separate the aggregated particles from the medium. Then, the medium or the particles are examined for the presence or amount of the analyte or an sbp member, the binding of which is affected by the presence of the analyte.

  本发明公开了一种从液体介质中分离物质的方法。该方法包括在磁性颗粒非特异性化学结合的条件下，将含有物质的液体介质与磁性颗粒结合。然后，将介质置于磁场梯度下，将颗粒从介质中分离出来。首选的非特异性结合是通过颗粒之间的电荷相互作用实现的，通常是通过多离子试剂。本发明的方法特别适用于从水悬浮液中分离细胞和微生物，以及测定疑似含有分析物的样品中的分析物。分析物是特异性结合对（sbp）的成员。样品在检测介质中与磁性颗粒和与分析物互补的 sbp 成员结合。检测介质中必须包含能与被分析物或其互补的 sbp 成员特异性结合的磁性或非磁性颗粒。在使磁性颗粒非特异性聚集或使磁性颗粒和非磁性颗粒共同聚集（如果存在非磁性颗粒）的条件下进行组合。将检测介质置于磁场梯度下，使聚集的颗粒与介质分离。然后，检测介质或颗粒中分析物或 sbp 成员的存在或数量，分析物或 sbp 成员的结合会受到分析物存在的影响。