1,4-phenylenebis[(3-nitrophenyl)methanone] | 80213-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,4-phenylenebis[(3-nitrophenyl)methanone]
• 英文别名: [4-(3-Nitrobenzoyl)phenyl]-(3-nitrophenyl)methanone
• CAS: 80213-65-6
• 化学式: C₂₀H₁₂N₂O₆
• 分子量: 376.325
• InChiKey: JCYGSVRRIFFJPN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  126
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  1,4-bis(trimethylstannyl)benzene 、 间硝基苯甲酰氯 以 邻二氯苯 为溶剂， 反应 7.0h， 以45%的产率得到1,4-phenylenebis[(3-nitrophenyl)methanone]
  参考文献：
  名称：

  Efficient Catalyst-Free Bi- And Triaroylation of Aromatic Rings in a Single Step

  摘要：

  The exceptional leaving group ability of the trimethylstannyl group in electrophilic aromatic substitutions makes possible the synthesis, in a single step, of bi- and triaroylarenes through the catalyst-free, regioselective reaction of bi- and tristannylarenes with different aroyl halides in o-dichlorobenzene as solvent. Specific di- and triketones are obtained in good to excellent yields (45-83%).

  DOI：

  10.1021/jo801890e

文献信息

• Efficient Catalyst-Free Bi- And Triaroylation of Aromatic Rings in a Single Step
  作者：Marcos J. Lo Fiego、Mercedes A. Badajoz、Gustavo F. Silbestri、María T. Lockhart、Alicia B. Chopa

  DOI：10.1021/jo801890e

  日期：2008.11.21

  The exceptional leaving group ability of the trimethylstannyl group in electrophilic aromatic substitutions makes possible the synthesis, in a single step, of bi- and triaroylarenes through the catalyst-free, regioselective reaction of bi- and tristannylarenes with different aroyl halides in o-dichlorobenzene as solvent. Specific di- and triketones are obtained in good to excellent yields (45-83%).