2-phenyl-3'-(4-hydroxyphenyl)-3-(2-hydroxyphenyl)phthalimidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-phenyl-3'-(4-hydroxyphenyl)-3-(2-hydroxyphenyl)phthalimidine
• 英文别名: 2-phenyl-3-(4-hydroxyphenyl)-3-(2-hydroxyphenyl)phthalimidine；N-phenyl phenolphthalein bisphenol；3-(2-Hydroxyphenyl)-3-(4-hydroxyphenyl)-2-phenylisoindol-1-one
• 化学式: C₂₆H₁₉NO₃
• 分子量: 393.442
• InChiKey: IAECBVHEHOQZPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  30
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯酐 在 aluminum (III) chloride 作用下， 以 邻二氯苯 、 1,1,2,2-四氯乙烷 为溶剂， 反应 21.5h， 生成 2-phenyl-3'-(4-hydroxyphenyl)-3-(2-hydroxyphenyl)phthalimidine 、 3,3-双(4-羟基苯基)-2-苯基丙-1-酮
  参考文献：
  名称：

  METHODS OF MANUFACTURE OF 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES

  摘要：

  一种制造2-烃基-3,3-双(羟基芳基)邻酰亚胺组合物的方法包括：在催化剂和可选的溶剂存在下，在升高的温度下将式(2)的邻酰亚胺与式(3)的酚反应，以形成2-烃基-3,3-双(羟基芳基)邻酰亚胺组合物，其中2-烃基-3,3-双(羟基芳基)邻酰亚胺组合物包括式(1)的2-烃基-3,3-双(羟基芳基)邻酰亚胺，式中(1)，(2)和(3)中，R1为氢，C1-6烷基，C1-6烷氧基或苯基，可选地取代为1至5个C1-6烷基，R2和R3的每个出现独立地为C1-6烷基，p和q独立地为0至4。

  公开号：

  US20160340307A1

文献信息

• METHODS FOR PRODUCING AND PURIFYING 2-HYDROCARBYL-3,3-BIS(4-HYDROXYARYL)PHTHALIMIDINE MONOMERS AND POLYCARBONATES DERIVED THEREFROM
  申请人：Basale Rajshekhar

  公开号：US20080242873A1

  公开（公告）日：2008-10-02

  Disclosed herein is a method comprising reacting a phenolphthalein material and a primary hydrocarbyl amine in the presence of an acid catalyst to form a reaction mixture comprising 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine, wherein the phenolphthalein material comprises greater than or equal to 99 weight percent phenolphthalein, based on the total weight of the phenolphthalein material; quenching the reaction mixture and treating the quenched reaction mixture to obtain a first solid. The first solid is purified by a combination of techniques to produce a solid comprising 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine with sufficient purity to be used as a monomer in the synthesis of clear polymers.

  本文公开了一种方法，包括在酸催化剂存在下，将酚酞材料与一种一次烷基胺反应，形成包含2-烷基-3,3-双(4-羟基芳基)酞酰亚胺的反应混合物，其中酚酞材料包括按总重量计占酚酞材料总重量的大于或等于99重量百分比的酚酞；淬灭反应混合物并处理淬灭后的反应混合物以获得第一固体。通过一系列技术将第一固体纯化，以产生含有足够纯度的2-烷基-3,3-双(4-羟基芳基)酞酰亚胺的固体，可用作合成透明聚合物的单体。
• [EN] METHODS OF MANUFACTURE OF 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES<br/>[FR] PROCÉDÉS DE PRÉPARATION DE 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTALIMIDINES
  申请人：SABIC GLOBAL TECHNOLOGIES BV

  公开号：WO2015107467A1

  公开（公告）日：2015-07-23

  A method for the manufacture of a 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidine composition comprises: reacting a phthalimide of formula (2) with a phenol of formula (3) I (2) I (3) in the presence of a catalyst and optionally a solvent at an elevated temperature to form the 2- hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidine composition, wherein the 2-hydrocarbyl-3,3- bis(hydroxyaryl)phthalimidine composition comprises a 2-hydrocarbyl-3,3- bis(hydroxyaryl)phthalimidine of formula (1) I (1) wherein in formulas (1), (2) and (3), R1 is hydrogen, C1-6 alkyl, C1-6 alkoxy, or phenyl optionally substituted with 1 to 5 C 1-6 alkyls, each occurrence of R2 and R3 is independently a C1-6 alkyl, and p and q are independently 0 to 4.

  一种制备2-烷基-3,3-双(羟基芳基)邻酰亚胺组合物的方法包括：在催化剂和可选溶剂的存在下，在升高的温度下将化学式（2）的邻酰亚胺与化学式（3）的酚反应，形成2-烷基-3,3-双(羟基芳基)邻酰亚胺组合物，其中2-烷基-3,3-双(羟基芳基)邻酰亚胺组合物包括化学式（1）I（1）的2-烷基-3,3-双(羟基芳基)邻酰亚胺，其中在化学式（1），（2）和（3）中，R1为氢，C1-6烷基，C1-6烷氧基或苯基，可选地取代1至5个C1-6烷基，R2和R3的每个出现独立地是C1-6烷基，p和q独立地为0至4。
• Methods for purifying 2-aryl-3,3-bis(hydroxyaryl)phthalimidines
  申请人：SABIC GLOBAL TECHNOLOGIES B.V.

  公开号：US10005884B2

  公开（公告）日：2018-06-26

  Methods for synthesizing and purifying 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidine compounds are provided. The method includes heating a reaction mixture including a phenolphthalein, a primary aryl amine, and an acid catalyst to form a phthalimidine; precipitating the phthalimidine from the reaction mixture to provide a crude phthalimidine; providing a solution including the crude phthalimidine, an additive, and at least one solvent; contacting the solution with one or more purification agents to provide a treated solution; precipitating and recovering a phthalimidine adduct from the treated solution; and recovering a purified phthalimidine compound from the adduct.

  本发明提供了合成和纯化 2-芳基-3,3-双(4-羟基芳基)酞脒化合物的方法。该方法包括加热包括酚酞、伯芳基胺和酸催化剂的反应混合物以形成酞脒，从反应混合物中沉淀酞脒以提供粗酞脒，提供包括粗酞脒，添加剂和至少一种溶剂的溶液；将溶液与一种或多种纯化剂接触，以提供处理溶液；从处理溶液中沉淀并回收酞脒加合物；以及从加合物中回收纯化的酞脒化合物。
• Flame retardant resin blends based on polymers derived from 2-hydrocarbyl-3,3-Bis(4-Hydroxyaryl)Phthalimidine monomers
  申请人：SABIC Innovative Plastics IP B.V.

  公开号：EP1582549B1

  公开（公告）日：2011-03-09
• POLYESTER-POLYCARBONATE BLENDS
  申请人：Chakravarti Shreyas

  公开号：US20080161507A1

  公开（公告）日：2008-07-03

  A composition of matter comprising a thermoplastic resin composition derived from (i) about 20 weight percent to about 80 weight percent of a polyester derived from a diol comprising cyclohexane dimethanol and a diacid; (ii) about 5 weight percent to about 80 weight percent of a copolycarbonate derived from about 20 weight percent to about 70 weight percent of a 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidine and from about 30 weight percent to about 80 weight percent of a second aromatic dihydroxy compound; (iii) about 0 weight percent to about 70 weight percent of a thermoplastic resin, C wherein the thermoplastic resin C is selected from the group consisting of a homopolycarbonate, a poly(estercarbonate), a poly(arylatecarbonate) and combinations thereof, and wherein the resin composition is transparent is disclosed. Also disclosed is a process to prepare this composition and articles therefrom.