N,4-dimethyl-N-[(Z)-3-phenylprop-2-enyl]benzenesulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,4-dimethyl-N-[(Z)-3-phenylprop-2-enyl]benzenesulfonamide
• 化学式: C₁₇H₁₉NO₂S
• 分子量: 301.409
• InChiKey: WHJSCONWHDGDDH-TWGQIWQCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.33
• 重原子数：
  21.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  37.38
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  alpha-乙烯基苄基乙酸酯 、 N-甲基对甲苯磺酰胺 在 十二羰基三钌 、 2-二苯基膦苯甲酸 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 1,4-二氧六环 为溶剂， 反应 12.0h， 以70%的产率得到N-cinnamyl-N,4-dimethylbenzenesulfonamide
  参考文献：
  名称：

  Ruthenium-catalyzed linear selective allylic aminations of monosubstituted allyl acetates

  摘要：

  The ruthenium-catalyzed highly linear selective allylic amination of monosubstituted allylic acetates with secondary amines was developed. The regioselectivity was controlled by the RU3(CO)(12)/2-DPPBA catalyst, and a linear-type aminated product was obtained as a single regioisomer. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.002

文献信息

• Ruthenium-catalyzed linear selective allylic aminations of monosubstituted allyl acetates
  作者：Motoi Kawatsura、Fumio Ata、Takuya Hirakawa、Shuichi Hayase、Toshiyuki Itoh

  DOI：10.1016/j.tetlet.2008.06.002

  日期：2008.8

  The ruthenium-catalyzed highly linear selective allylic amination of monosubstituted allylic acetates with secondary amines was developed. The regioselectivity was controlled by the RU3(CO)(12)/2-DPPBA catalyst, and a linear-type aminated product was obtained as a single regioisomer. (C) 2008 Elsevier Ltd. All rights reserved.