二乙基(2-羟基乙基)铵乙酸盐 | 13695-28-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 二乙基(2-羟基乙基)铵乙酸盐
• 英文名称: N,N-diethylethanolammonium acetate
• 英文别名: Diethyl(2-hydroxyethyl)ammonium acetate；acetic acid;2-(diethylamino)ethanol
• CAS: 13695-28-8
• 化学式: C₂H₄O₂*C₆H₁₅NO
• 分子量: 177.244
• InChiKey: MLVIXBBRXGJUJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.34
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  64.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  溶剂黄146 、 二乙氨基乙醇 以 甲醇 为溶剂， 反应 26.0h， 生成 二乙基(2-羟基乙基)铵乙酸盐
  参考文献：
  名称：

  Cleaner enzymatic production of biodiesel with easy separation procedures triggered by a biocompatible hydrophilic ionic liquid

  摘要：

  一种生物相容性和亲水性离子液体被发现能够有效促进不同油资源的酶促生物柴油生产，产率优异。

  DOI：

  10.1039/c9gc03796a

文献信息

• Biocompatible Ionic Liquid Promote One-Pot Synthesis of 2-Amino-4H-Chromenes Under Ambient Conditions
  作者：Anlian Zhu、Qixing Li、Wanlu Feng、Dongshuang Fan、Lingjun Li

  DOI：10.1007/s10562-020-03332-7

  日期：2021.3

  The synthesis of 2-amino-4H-chromenes through one-pot multicomponent reactions has received great attention due to the high atom efficiency and the broad bioactivities of the products. Here, the catalytic performances of a series of functional ionic liquids towards this type of reaction were investigated and the results showed that the ionic liquid, choline acetate ([Choline][Ac]), could efficiently

  通过一锅多组分反应合成2-氨基-4H-色烯由于其高原子效率和广泛的生物活性而备受关注。在这里，研究了一系列功能性离子液体对此类反应的催化性能，结果表明离子液体醋酸胆碱（[Choline][Ac]）可以在室温下有效地促进该反应，而无需有机溶剂。该反应易于进行，后续处理程序非常简单。通过萃取和洗涤程序即可获得纯品，无需柱分离程序。有趣的是，这个反应系统可以很容易地放大到几克，这表明它在工业应用中的前景。此外，离子液体 [Choline][Ac] 可以很容易地由廉价且具有生物相容性的材料制备，并且可以回收和再利用至少五个循环。在室温下，在乙酸胆碱的催化下，各种醛、丙二腈和活化酚可以转化为相应的 2-氨基-4H-色烯，分离产率从良好到极好。
• Ionic Liquids
  申请人：Walker Adam John

  公开号：US20080221361A1

  公开（公告）日：2008-09-11

  The invention provides ionic liquids and processes for their preparation. The liquids may either comprise a cation of the formula (I); N + HR 1 R 2 R 3 (I) wherein R 1 is a group —R 4 —O—R 5 ; R 2 and R 3 are each independently either hydrogen or hydrocarbyl, R 2 and R 3 may be joined together with the N to form a heterocyclic group; R 4 is a divalent hydrocarbyl radical; and R 5 is hydrocarbyl; or a cation of the formula (II), N+HR6R7R8 (II) wherein R 6 is an alkanolyl group; R 7 is a hydrocarbyl group; and R 8 is either hydrogen or hydrocarbyl, or R 7 and R 8 may be joined together with the N to form a heterocyclic group.

  本发明提供了离子液体及其制备方法。这些液体可以包括公式（I）的阳离子; N+HR1R2R3（I），其中R1是一个基团-R4-O-R5; R2和R3分别是氢或烃基，R2和R3可以与N结合形成杂环基团; R4是一个二价的烃基基团; R5是烃基; 或者是公式（II）的阳离子，N+HR6R7R8（II），其中R6是烷基醇基团; R7是烃基基团; R8是氢或烃基，或者R7和R8可以与N结合形成杂环基团。
• Diethanolamine and N,N-diethylethanolamine ionic liquids as precatalyst-precursors and reaction media in green Heck reaction protocol
  作者：Zorica D. Petrović、Dušica Simijonović、Vladimir P. Petrović、Svetlana Marković

  DOI：10.1016/j.molcata.2010.05.010

  日期：2010.7

  It was found that Heck reaction with PdCl2 in diethanolamine and N,N-diethylethanolamine ionic liquids (ILs) is more efficient than analogous reactions performed in classical organic solvents. The used Its facilitate solubility of the Pd(II) precatalysts, increase catalyst stability during the reaction, and function as reaction media, bases, precatalyst-precursors, good coordinating ligands, and mobile support for active Pd species. Thus, Heck reaction occurs without additional solvents, ligands and bases, that makes experimental procedure much simpler. Our DFT investigation provides mechanistic insight into the formation of the trans-[PdCl2(DEA)(2)] complex that acts as a precatalyst. (C) 2010 Elsevier B.V. All rights reserved.
• US4076662A
  申请人：——

  公开号：US4076662A

  公开（公告）日：1978-02-28