2-fluoro-1,3-dioxolane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 英文名称: 2-fluoro-1,3-dioxolane
• 英文别名: Fluorodioxolane
• 化学式: C₃H₅FO₂
• 分子量: 92.0699
• InChiKey: YCZLECHWMBITQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,3-二氧戊环 在 triethylamine pentahydrogen fluoride salt 作用下， 以20%的产率得到2-fluoro-1,3-dioxolane
  参考文献：
  名称：

  Electroorganic synthesis under solvent-free conditions. Highly regioselective anodic monofluorination of cyclic ethers, lactones, and a cyclic carbonate

  摘要：

  Regioselective anodic fluorination of cyclic ethers, lactones, and a cyclic carbonate in Et4NF.nHF (n = 4, 5) and Et3N.5HF without a solvent was successfully carried out to give the corresponding monofluorinated products in moderate yields. This is the first report of direct electochemical fluorination of cyclic ethers, lactones, and a cyclic carbonate using anodic fluorination. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00047-3

文献信息

• Electroorganic synthesis under solvent-free conditions. Highly regioselective anodic monofluorination of cyclic ethers, lactones, and a cyclic carbonate
  作者：Masaru Hasegawa、Hideki Ishii、Toshio Fuchigami

  DOI：10.1016/s0040-4039(02)00047-3

  日期：2002.2

  Regioselective anodic fluorination of cyclic ethers, lactones, and a cyclic carbonate in Et4NF.nHF (n = 4, 5) and Et3N.5HF without a solvent was successfully carried out to give the corresponding monofluorinated products in moderate yields. This is the first report of direct electochemical fluorination of cyclic ethers, lactones, and a cyclic carbonate using anodic fluorination. (C) 2002 Elsevier Science Ltd. All rights reserved.