diethylaminoheptene | 30432-24-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: diethylaminoheptene
• 英文别名: Diaethyl--amin；N-(1-Heptenyl)diethylamin；diethyl-hept-1-enyl-amine；1-Diaethylamino-hepten-(1)；Diaethyl-hept-1-enyl-amin；N,N-diethylhept-1-en-1-amine
• CAS: 30432-24-7
• 化学式: C₁₁H₂₃N
• 分子量: 169.31
• InChiKey: DCXKOYVJZCOLGV-UHFFFAOYSA-N

物化性质

• 沸点：
  134-140 °C(Press: 110 Torr)
• 密度：
  0.8 g/cm3(Temp: 16.8 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  diethylaminoheptene 在 platinum(IV) oxide 、 环己烷 作用下， 生成 N,N-二乙基-1-庚胺
  参考文献：
  名称：

  Mannich; Handke; Roth, Chemische Berichte, 1936, vol. 69, p. 2122

  摘要：

  DOI：
• 作为产物：
  描述：

  庚醛 生成 diethylaminoheptene
  参考文献：
  名称：

  Heiszwolf,G.J.; Kloosterziel,H., Recueil des Travaux Chimiques des Pays-Bas, 1970, vol. 89, p. 1217 - 1228

  摘要：

  DOI：

文献信息

• Activation of Fmoc-Protected <i>N</i>,<i>O</i>-Acetals Using Trimethylsilyl Halides: Mechanistic and Synthetic Studies
  作者：Nicholas C. Boaz、Nathaniel C. Bair、Thanh T. Le、Timothy J. Peelen

  DOI：10.1021/ol100494z

  日期：2010.6.4

  O-acetals yields reactive intermediates capable of efficiently adding to a variety of enamines. NMR studies have provided evidence that a stable halomethyl carbamate intermediate forms in solution. Good yields are obtained over a broad range of enamine nucleophiles encompassing both cyclic and acyclic ketone-derived and aldehyde-derived enamines. Preliminary studies suggest that the enamine additions occur

  Fmoc保护的N，O-缩醛的三甲基甲硅烷基卤化物活化产生能够有效地添加到多种烯胺中的反应性中间体。NMR研究提供了证据，表明在溶液中形成了稳定的氨基甲酸卤甲基酯中间体。在宽范围的烯胺亲核试剂上都获得了良好的收率，包括环和非环状的酮衍生和醛衍生的烯胺。初步研究表明，烯胺的添加是通过协调一致的S N 2型机制发生的。
• Reaction of 5-Arylidenerhodamine Derivatives with 1-Piperidinocyclohexene and Diethylaminoheptene Enamines
  作者：Mahmoud A. Abdel-Rahman

  DOI：10.1135/cccc19933009

  日期：——

  The present paper deals with the reaction of arylidenerhodamine derivatives Ia - Id with enamines 1-piperidinocyclohexane IIa and diethylaminoheptene IIb, stronger nucleophiles than 1-morpholinocyclohexane described earlier.

  本文讨论了芳基亚乙烯基罗丹明衍生物Ia-Id与1-哌啶环己烷IIa和二乙氨基庚烯IIb的反应，这两种试剂是比之前描述的1-吗啡啶环己烷更强的亲核试剂。
• Tiollais,R. et al., Bulletin de la Societe Chimique de France, 1964, p. 1205 - 1206
  作者：Tiollais,R. et al.

  DOI：——

  日期：——
• Structure of Monocrotaline. VII.¹ Structure of Retronecine and Related Bases
  作者：Roger Adams、Marvin Carmack、J. E. Mahan

  DOI：10.1021/ja01263a020

  日期：1942.11
• Rhodium complex encapsulated functionalized hexagonal mesoporous silica for heterogeneous hydroaminomethylation
  作者：N. Sudheesh、Ram S. Shukla

  DOI：10.1016/j.apcata.2012.12.021

  日期：2013.2

  HRh(CO)(PPh3)(3) complex was encapsulated into the pores of amino functionalized hexagonal mesoporous silica. The catalyst was characterized by physico-chemical techniques like P-XRD, P-31-CPMAS NMR, FT-IR, SEM, ICP and N-2 adsorption analysis. The catalyst was active for hydroaminomethylation and a variety of alkenes and amines were used as reactants for hydroaminomethylation. The catalyst afforded to achieve 100% conversion with high (>95%) selectivity to corresponding amines. Parametric variations were performed by taking 1-hexene and morpholine as representative reactants for the study of catalyst amount, temperature, pressure and 1-hexene:morpholine ratio. Significant amounts of aldehydes and enamines were observed during the course of the reaction indicating that there could be two possible rate determining steps. The catalyst was effectively recycled up to five times without much loss in its activity and selectivity. (C) 2012 Elsevier B.V. All rights reserved.