methyl-[ergostatetraen-(5.7.9(11)22t)-yl-(3β)]-ether | 5895-66-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: methyl-[ergostatetraen-(5.7.9(11)22t)-yl-(3β)]-ether
• 英文别名: 3β-Methoxy-24β_F-methyl-cholestatetraen-(5.7.9(11).22t)；Methyl-[ergostatetraen-(5.7.9(11)22t)-yl-(3β)]-aether；(10S)-3c-Methoxy-10r.13c-dimethyl-17c-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(14tH)-2.3.4.10.12.13.14.15.16.17-decahydro-1H-cyclopenta[a]phenanthren；3β-Methoxy-ergostatetraen-(5.7.9(11).22t)；Dehydroergosterol methyl ether；(3S,10S,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-3-methoxy-10,13-dimethyl-2,3,4,12,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene
• CAS: 5895-66-9
• 化学式: C₂₉H₄₄O
• 分子量: 408.668
• InChiKey: GEHJKQAPQBWVMD-SAMWLVSJSA-N

物化性质

• 沸点：
  507.351±49.00 °C(Press: 760.00 Torr)(predicted)
• 密度：
  0.993±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  麦角固醇 在 甲醇 、 sodium hydroxide 、 乙醇 、 mercury(II) diacetate 、 silver(l) oxide 作用下， 生成 methyl-[ergostatetraen-(5.7.9(11)22t)-yl-(3β)]-ether
  参考文献：
  名称：

  The Idle Column Method: Design Construction, Properties and Comparisons

  摘要：

  Taguchi's idle column method for constructing arrays is investigated and generalized. A general construction method is proposed via a necessary and sufficient condition on two-level orthogonal arrays to which the method is applicable. A method is developed for identifying the idle column and pairs of columns in the arrays. Mixed two- and three-level idle column arrays with 64 or fewer runs are tabulated. Some guidelines are offered on when the idle column arrays should be used and when they should be replaced by orthogonal main-effect plans or D-optimal designs.

  DOI：

  10.1198/004017002188618545

文献信息

• The Idle Column Method: Design Construction, Properties and Comparisons
  作者：Longcheen Huwang、C F J Wu、C H Yen

  DOI：10.1198/004017002188618545

  日期：2002.11

  Taguchi's idle column method for constructing arrays is investigated and generalized. A general construction method is proposed via a necessary and sufficient condition on two-level orthogonal arrays to which the method is applicable. A method is developed for identifying the idle column and pairs of columns in the arrays. Mixed two- and three-level idle column arrays with 64 or fewer runs are tabulated. Some guidelines are offered on when the idle column arrays should be used and when they should be replaced by orthogonal main-effect plans or D-optimal designs.