1,1,1-三氯-2,2-二甲基-丙烷 | 56087-10-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 1,1,1-三氯-2,2-二甲基-丙烷
• 英文名称: 1,1,1-trichloro-2,2-dimethyl-propane
• 英文别名: 1,1,1-Trichlor-2,2-dimethylpropan；1,1,1-Trichloro-2,2-dimethylpropane
• CAS: 56087-10-6
• 化学式: C₅H₉Cl₃
• 分子量: 175.485
• InChiKey: BAWSQRWMUMVTEM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  以 四氯化碳 为溶剂， 生成 氯仿 、 1,1,1-三氯-2,2-二甲基-丙烷 、 异丁烯
  参考文献：
  名称：

  Pouwels, Petra J. W.; Kaptein, Robert, Zeitschrift fur Physikalische Chemie, 1993, vol. 182, # 1/2, p. 143 - 154

  摘要：

  DOI：

文献信息

• HETEROCYCLIC CETP INHIBITORS
  申请人：Salvati E. Mark

  公开号：US20070161685A1

  公开（公告）日：2007-07-12

  Compounds of formula Ia and Ib wherein A, B, C and R 1 are described herein.

  式Ia和Ib的化合物 其中A、B、C和R1 如本文所述。
• METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL
  申请人：Tsuda Toshiro

  公开号：US20130253228A1

  公开（公告）日：2013-09-26

  An object of the present invention is to provide a method for manufacturing an optically active menthol having fewer steps, which generates less environmentally polluting waste because a catalytic reaction is involved in all of the steps, and is capable of saving a production cost. The present invention relates to a method for manufacturing an optically active menthol, including the following steps: A-1) asymmetrically hydrogenating at least one of geranial and neral to thereby obtain an optically active citronellal, B-1) conducting a ring-closure reaction of the optically active citronellal in the presence of an acid catalyst to thereby obtain an optically active isopulegol, and C-1) hydrogenating the optically active isopulegol to thereby obtain an optically active menthol.

  本发明的目的是提供一种制造具有较少步骤的光学活性薄荷醇的方法，因为所有步骤都涉及催化反应，所以产生的环境污染废物较少，并且能够节省生产成本。本发明涉及一种制造光学活性薄荷醇的方法，包括以下步骤：A-1）不对称地氢化至少一种香叶醛和柠檬醛以获得光学活性柠檬醛，B-1）在酸催化剂存在下对光学活性柠檬醛进行环闭合反应，从而获得光学活性异薄荷醇，以及C-1）对光学活性异薄荷醇进行氢化以获得光学活性薄荷醇。
• Process for the preparation of acrylates
  申请人：THE BRITISH PETROLEUM COMPANY P.L.C.

  公开号：EP0468643A1

  公开（公告）日：1992-01-29

  (Meth)acrylate esters containing an amine group blocked by a carbonate derivative having, e.g. t-butyl group, are made by reaction of a methyl or ethyl (meth)acrylate with a hydroxy carbamate derivative containing, e.g. a t-butyl group. The hydroxy carbamate derivative may be made by reacting an alkanolamine with an alkyl aryl carbonate in which the alkyl group is, e.g. t-butyl.

  含有碳酸酯衍生物阻塞的胺基团的（甲基）丙烯酸酯，例如t-丁基基团，是通过将甲基或乙基（甲基）丙烯酸酯与含有羟基氨甲酸酯衍生物反应制得，例如t-丁基基团。羟基氨甲酸酯衍生物可以通过将烷基胺与烷基芳基碳酸酯反应制备而成，其中烷基基团为t-丁基基团。
• ALUMINUM CATALYST
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20150315110A1

  公开（公告）日：2015-11-05

  An aluminum catalyst is obtained by reacting at least one compound of a specific alkylaluminum compound and a specific hydridoaluminum compound with a specific hydroxy compound. The specific hydroxyl compound is a specific 2-cycloalkyl-6-arylphenol or a specific di(2-cycloalkyl-6-arylphenol). A method for producing isopulegol or optically active isopulegol includes selectively cyclizing citronellal using the aluminum catalyst.

  通过将特定的烷基铝化合物和特定的氢化铝化合物至少与一种特定的羟基化合物反应，可以获得铝催化剂。特定的羟基化合物是特定的2-环烷基-6-芳基酚或特定的二(2-环烷基-6-芳基酚)。使用铝催化剂有选择地使柠檬醛环化，从而生产异莰醇或光学活性异莰醇的方法。
• ORGANOALUMINUM COMPOUND
  申请人：ITOH Hisanori

  公开号：US20110295031A1

  公开（公告）日：2011-12-01

  A catalyst for obtaining isopulegol of high diastereoselectivity by highly selective cyclization reaction of citronellal is provided. The present invention relates to an organoaluminum compound obtained by reacting at least one organoaluminumoxy compound selected from the group consisting of chain aluminoxanes, cyclic aluminoxanes and bis(dialkylaluminumoxy)alkylboranes, with at least one hydroxy compound selected from the group consisting of diarylphenols, bis(diarylphenol) compounds, biaryldiols, dimethanols and silanols.

  本发明提供了一种催化剂，用于通过高度选择性的环化反应从香茅醛中获得高对映选择性的异莰醇。本发明涉及通过将链状铝氧烷、环状铝氧烷和双(二烷基氧基)烷基硼烷等组中至少一种有机铝氧化合物与二苯基酚、双(二苯基酚)化合物、联苯二醇、二甲醇和硅烷等组中至少一种羟基化合物反应而得到的有机铝化合物。