n-辛基甲基膦酸 | 1832-58-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 中文名称: n-辛基甲基膦酸
• 英文名称: Methylphosphonsaeure-mono-octylester
• 英文别名: Methyl(octoxy)phosphinic acid
• CAS: 1832-58-2
• 化学式: C₉H₂₁O₃P
• 分子量: 208.238
• InChiKey: GPGCPVFGIJFFAO-UHFFFAOYSA-N

物化性质

• 沸点：
  289.8±23.0 °C(Predicted)
• 密度：
  1.005 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  n-辛基甲基膦酸 生成 O,O'-dioctyl methylphosphonate
  参考文献：
  名称：

  Petrov,K.A. et al., Journal of general chemistry of the USSR, 1965, vol. 35, p. 723 - 726

  摘要：

  DOI：
• 作为产物：
  描述：

  甲基膦酞二氯 、 辛醇 生成 n-辛基甲基膦酸
  参考文献：
  名称：

  Evdakov,V.P.; Mizrakh,L.I., Journal of general chemistry of the USSR, 1964, vol. 34, p. 1860 - 1862

  摘要：

  DOI：

文献信息

• Polymer-supported sulfonated magnetic resin: an efficient reagent for esterification of O-alkyl alkylphosphonic-and carboxylic-acids
  作者：Ajay Kumar Purohit、Ajeet Kumar、Varoon Singh、Raghavender Goud D、Rajiv Jain、D.K. Dubey

  DOI：10.1016/j.tetlet.2014.10.086

  日期：2014.12

  A mild and efficient synthetic method has been developed for the esterification of O-alkyl alkylphosphonic-and carboxylic-acids using polymer-supported sulfonated magnetic resins. Polymer-supported resins are recovered using an external magnet and reused several times.

  已经开发了一种温和而有效的合成方法，该方法使用聚合物负载的磺化磁性树脂对O-烷基烷基膦酸和羧酸进行酯化。使用外部磁体回收聚合物负载的树脂，并重复使用几次。
• PREPARATION, DERIVATIZATION WITH TRIMETHYLSILYLDIAZOMETHANE, AND GC/MS ANALYSIS OF A “POOL” OF ALKYL METHYLPHOSPHONIC ACIDS FOR USE AS QUALITATIVE STANDARDS IN SUPPORT OF COUNTERTERRORISM AND THE CHEMICAL WEAPONS CONVENTION
  作者：Michael D. Crenshaw、David B. Cummings

  DOI：10.1080/10426500490459632

  日期：2004.6

  There are hundreds of nerve agents in the class of alkyl methylphosphonofluoridates covered by Schedule 1 of the CWC (Chemical Weapons Convention). Hydrolysis of these sarin-like nerve agents results in all equal number of alkyl methylphosphonic acids. These allkyl methylphosphonic acids are persistent and provide good evidence of specific agent production or use. In order to support the CWC and counterterrorism activities, it is desirable to have ready access to each of these hydrolysis products for use as qualitative standards. A means for simultaneously producing multiple alkyl methylphosphonates from methylphosphonic acid and the corresponding alcohols was developed. Derivatization of these alkyl methylphosphonic acids with trimethylsilyldiazomethane yields the corresponding methyl esters which are suitable for GC/MS analysis.
• Evdakov,V.P.; Mizrakh,L.I., Journal of general chemistry of the USSR, 1964, vol. 34, p. 1860 - 1862
  作者：Evdakov,V.P.、Mizrakh,L.I.

  DOI：——

  日期：——
• Petrov,K.A. et al., Journal of general chemistry of the USSR, 1965, vol. 35, p. 723 - 726
  作者：Petrov,K.A. et al.

  DOI：——

  日期：——