1,1-dichloro-2-propyl cyclopropane | 15997-08-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 英文名称: 1,1-dichloro-2-propyl cyclopropane
• 英文别名: 1,1-dichloro-2-propyl-cyclopropane；1,1-Dichlor-2-propyl-cyclopropan；2,2-Dichlor-1-propyl-cyclopropan；1,1-Dichloro-2-propylcyclopropane
• CAS: 15997-08-7
• 化学式: C₆H₁₀Cl₂
• 分子量: 153.051
• InChiKey: UKPAAUBRDPZZDQ-UHFFFAOYSA-N

物化性质

• 沸点：
  68.2-68.5 °C(Press: 46 Torr)
• 密度：
  1.14±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,1-dichloro-2-propyl cyclopropane 在 亚硝基硫酸 作用下， 以 硝基甲烷 为溶剂， 反应 3.0h， 生成 5-chloro-3-propylisoxazole 、 5-chloro-4-propylisoxazole
  参考文献：
  名称：

  Nitrosylsulfuric acid in the synthesis of 5-chloroisoxazoles from 1,1-dichlorocyclopropanes

  摘要：

  Nitrosylsulfuric acid is shown to be a usable reagent for the synthesis of 5-chioroisoxazoles from readily available 1,1-dichlorocyclopropanes via nitrosation-heterocyclization reaction. A cytotoxicity of some of the prepared 5-chloroisoxazoles towards MCF7, A549, HEK293T and VA13 cell lines was evaluated.

  DOI：

  10.1016/j.mencom.2019.07.021
• 作为产物：
  描述：

  1-(2,2-Dichlor-cyclopropyl)-propadien 生成 1,1-dichloro-2-propyl cyclopropane
  参考文献：
  名称：

  Slobodin,Ya.M.; Egenburg,I.Z., Journal of Organic Chemistry USSR (English Translation), 1970, vol. 6, p. 2638

  摘要：

  DOI：

文献信息

• [EN] AZOLE DERIVATIVES AND METHODS FOR PRODUCING THE SAME, INTERMEDIATE COMPOUNDS FOR THE DERIVATIVES AND METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS CONTAINING THE DERIVATIVES<br/>[FR] DÉRIVÉS AZOLE ET LEURS PROCÉDÉS DE PRODUCTION, COMPOSÉS INTERMÉDIAIRES POUR SYNTHÉTISER LES DÉRIVÉS ET LEURS PROCÉDÉS DE PRODUCTION, ET AGENTS AGRO-HORTICOLES ET AGENTS DE PROTECTION DE PRODUITS INDUSTRIELS CONTENANT LES DÉRIVÉS
  申请人：KUREHA CORP

  公开号：WO2011070742A1

  公开（公告）日：2011-06-16

  To provide an azole derivative which is contained as an active ingredient in an agro-horticultural agent having an excellent controlling effect on diseases. An azole derivative according to the invention is represented by Formula (I), wherein R1 and R2 are same or different, and each denotes a substituted C3-C6 cycloalkyl group or a C1-C4 alkyl group substituted with the substituted C3-C6 cycloalkyl group; and A denotes a nitrogen atom or a methyne group.

  为了提供一种唑类衍生物，该衍生物作为农业园艺药剂中的活性成分，对疾病具有出色的控制效果。根据本发明，所述唑类衍生物由式(I)表示，其中R1和R2相同或不同，每个表示取代的C3-C6环烷基或取代的C3-C6环烷基取代的C1-C4烷基；A表示氮原子或亚甲基基团。
• A New Phase Transfer Reagent for the Addition of Dichlorocarbene to Olefins Under Mild PTC Conditions
  作者：J. Paul Jayachandran、Maw-Ling Wang

  DOI：10.1080/00397919908085884

  日期：1999.12.1

  to a novel water soluble phase transfer reagent, Diquat (Dq-Br), viz., 2-benzilidine- N,N,N,N',N',N'- hexaethyl propane-1,3 diammonium dibromide and its utility in various dichlorocarbenations to olefins are described.

  摘要 一种新型水溶性相转移试剂敌草快 (Dq-Br) 的三步合成路线，即 2-benzilidine-N,N,N,N',N',N'-六乙基丙烷-1， 3 二溴化二铵及其在烯烃的各种二氯碳化反应中的应用。
• Triazolopyrimdines
  申请人：Gebauer Olaf

  公开号：US20070179162A1

  公开（公告）日：2007-08-02

  The invention relates to novel triazolopyrimidines of formula (I), in which R 1 , R 2 , R 3 and X are defined as cited in the description, to a method for producing said substances and to their use for controlling undesirable micro-organisms. The invention also relates to novel intermediate products of the formulae (II), (VI), (VII-a) and (VII-b), in addition to methods for producing said substances.

  该发明涉及公式（I）中的新型三唑吡咯啉化合物，其中R1、R2、R3和X的定义如描述中所述，以及生产这些物质的方法和它们用于控制不良微生物的用途。该发明还涉及公式（II）、（VI）、（VII-a）和（VII-b）的新型中间体，以及生产这些物质的方法。
• Experimental Proof of the Non-Least-Motion Cycloadditions of Dichlorocarbene to Alkenes:  Kinetic Isotope Effects and Quantum Mechanical Transition States
  作者：Amy E. Keating、Steven R. Merrigan、Daniel A. Singleton、K. N. Houk

  DOI：10.1021/ja981427x

  日期：1999.4.1

  High-precision experimental kinetic isotope effects were measured at natural abundance for the cycloaddition of dichlorocarbene to 1-pentene. These values were compared to isotope effects predicted for the addition of dichlorocarbene to propene at the B3LYP/6-31G* and B3LYP/6-311+G* levels. The results provide unambiguous evidence for a nonlinear attack in which bond formation is more advanced at the

  在自然丰度下测量了二氯卡宾环加成到 1-戊烯的高精度实验动力学同位素效应。将这些值与在 B3LYP/6-31G* 和 B3LYP/6-311+G* 水平下将二氯卡宾添加到丙烯中预测的同位素效应进行比较。结果为非线性攻击提供了明确的证据，其中在环加成过渡态的末端烯烃的未取代碳上更促进了键的形成。这是 40 多年前由 Skell 首次提出并通过量子力学计算预测的卡宾到烯烃的不对称、非最小运动方法的首次实验证实。
• AZOLE DERIVATIVES AND METHODS FOR PRODUCING THE SAME, INTERMEDIATE COMPOUNDS FOR THE DERIVATIVES AND METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS CONTAINING THE DERIVATIVES
  申请人：Sudo Keiichi

  公开号：US20120238762A1

  公开（公告）日：2012-09-20

  To provide an azole derivative which is contained as an active ingredient in an agro-horticultural agent having an excellent controlling effect on diseases. An azole derivative according to the invention is represented by Formula (I), wherein R 1 and R 2 are same or different, and each denotes a substituted C3-C6 cycloalkyl group or a C1-C4 alkyl group substituted with the substituted C3-C6 cycloalkyl group; and A denotes a nitrogen atom or a methyne group.

  提供一种含有杀菌效果优异的农业-园艺剂的活性成分的唑类衍生物。根据本发明，所述唑类衍生物由式（I）表示，其中R1和R2相同或不同，且每个都表示取代的C3-C6环烷基或取代的C3-C6环烷基取代的C1-C4烷基; A表示氮原子或甲亚基。