N,N-bis[2-[(1-tert-butyl-1,1-diemthylsilyl)oxy]ethyl]-N-phenylamine | 148717-08-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-bis[2-[(1-tert-butyl-1,1-diemthylsilyl)oxy]ethyl]-N-phenylamine
• 英文别名: N,N-Bis[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]benzenamine；N,N,N',N'-tetra(2-hydroxyethyl)-4,4'-tellurobisbenzenamine；N-N'-di(t-butyl-dimethylsiloxy-ethyl)aniline；Benzenamine, N,N-bis[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-；N,N-bis[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline
• CAS: 148717-08-2
• 化学式: C₂₂H₄₃NO₂Si₂
• 分子量: 409.76
• InChiKey: DEWAYKXYLJASKC-UHFFFAOYSA-N

物化性质

• 沸点：
  420.9±30.0 °C(Predicted)
• 密度：
  0.925±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.54
• 重原子数：
  27
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N,N-bis[2-[(1-tert-butyl-1,1-diemthylsilyl)oxy]ethyl]-N-phenylamine 在 甲醇 、 四乙基氯化铵 、 溴 作用下， 以 二氯甲烷 为溶剂， 以99%的产率得到2-[(4-bromo-phenyl)-(2-hydroxy-ethyl)-amino]-ethanol
  参考文献：
  名称：

  四乙基氯化铵/甲醇体系在温和条件下对苯胺溴化反应的区域选择性高

  摘要：

  报道了对位苯胺家族的单溴化的高效和高区域选择性。氯化四乙铵/甲醇用作助催化剂。

  DOI：

  10.1016/s0040-4039(00)60359-3
• 作为产物：
  描述：

  N,N-二羟乙基苯胺 、 叔丁基二甲硅基三氟甲磺酸酯 在 2,6-二甲基吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以99%的产率得到N,N-bis[2-[(1-tert-butyl-1,1-diemthylsilyl)oxy]ethyl]-N-phenylamine
  参考文献：
  名称：

  Mixed-Ligand Arenechromium Carbonyl Complexes as Electronic Modulators

  摘要：

  A number of mixed ligand eta(6) arenechromium carbonyl complexes have been prepared and investigated for their ability to effect electronic modulation of arene chemistry. In the case of an aniline-derived system, the arenechromium carbonyl complex is able to modulate the inductive capacity of the aniline nitrogen atom and thus, regulate its anchimeric ability. In the case of 8-phenylmenthol and benzyloxazolidinone derivatives, modulation of arene ar basicity is achieved, and results suggest that important vinylarene pi-pi interactions exist in acrylate derivatives of these chiral auxiliary systems.

  DOI：

  10.1021/jo9721103

文献信息

• WO2008/109701
  申请人：——

  公开号：——

  公开（公告）日：——
• Immunoassay element containing a diaryl telluride compound to increase its stability
  申请人：Ortho-Clinical Diagnostics, Inc.

  公开号：EP0747704B1

  公开（公告）日：2003-12-10
• High regioselectivity of bromination of anilines by tetraethylammonium chloride / methanol system as cocatalysts under mild conditions
  作者：Sophie Gervat、Eric Léonel、Jean-Yves Barraud、Victorin Ratovelomanana

  DOI：10.1016/s0040-4039(00)60359-3

  日期：1993.3

  An efficient and high regioselectivity for monobromination of a family of anilines in the para position is reported. Tetraethylammonium Chloride / Methanol are used as cocatalysts.

  报道了对位苯胺家族的单溴化的高效和高区域选择性。氯化四乙铵/甲醇用作助催化剂。
• Mixed-Ligand Arenechromium Carbonyl Complexes as Electronic Modulators
  作者：Graham B. Jones、Brant J. Chapman、Jude E. Mathews

  DOI：10.1021/jo9721103

  日期：1998.5.1

  A number of mixed ligand eta(6) arenechromium carbonyl complexes have been prepared and investigated for their ability to effect electronic modulation of arene chemistry. In the case of an aniline-derived system, the arenechromium carbonyl complex is able to modulate the inductive capacity of the aniline nitrogen atom and thus, regulate its anchimeric ability. In the case of 8-phenylmenthol and benzyloxazolidinone derivatives, modulation of arene ar basicity is achieved, and results suggest that important vinylarene pi-pi interactions exist in acrylate derivatives of these chiral auxiliary systems.