dichloromethylsilane | 42430-97-7

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: dichloromethylsilane
• 英文别名: (Dichloromethyl)silane
• CAS: 42430-97-7
• 化学式: CH₄Cl₂Si
• 分子量: 115.034
• InChiKey: UWGIJJRGSGDBFJ-UHFFFAOYSA-N

物化性质

• 沸点：
  82.3±30.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.11
• 重原子数：
  4
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  dichloromethylsilane 在 二氯甲烷 、 溶剂红 43 作用下， 反应 24.0h， 以99%的产率得到甲基三氯硅烷
  参考文献：
  名称：

  用二氯甲烷对中性曙红-Y-光催化硅烷氯化。

  摘要：

  氯硅烷是有机合成和材料科学中的多功能试剂。现在报道了在中性曙红Y作为氢原子转移光催化剂和二氯甲烷作为氯化剂的情况下，在可见光照射下氢硅烷定量转化为甲硅烷基氯的温和途径。在连续流微管反应器的辅助下，以高度选择性的方式实现了二氢硅烷和三氢硅烷的逐步氯化。使用曙红Y促进的通过光催化Si-H活化来获得甲硅烷基的能力为以方便和绿色的方式合成有价值的硅试剂提供了新的视角。

  DOI：

  10.1002/anie.201908556
• 作为产物：
  描述：

  二氯甲基三氯硅烷 在 lithium aluminium tetrahydride 、 二丁醚 作用下， 生成 dichloromethylsilane
  参考文献：
  名称：

  Kaesz; Stone, Journal of the Chemical Society, 1957, p. 1433

  摘要：

  DOI：
• 作为试剂：
  描述：

  反式-查耳酮 在 dichloromethylsilane 、 三氯化铁 作用下， 以 乙二醇二甲醚 为溶剂， 反应 3.0h， 以65%的产率得到(1E)-1,3-diphenylpropene
  参考文献：
  名称：

  氯化铁催化的羰基化合物脱氧氯化为卤化物

  摘要：

  脱氧氯化是将具有氧官能团的有机分子转化为氯化物的重要方法。羰基化合物与 PCl 或 WCl 的反应是制备氯乙烯、二氯化物或 1,1,2-三氯化物的众所周知的途径。~ 然而，羰基化合物直接转化为有机卤化物的方法很大程度上未开发。最近，Baba 及其同事报告称，In(OH) 是一种有效的催化剂，可通过在氯仿中使用氯二甲基硅烷以良好的收率对芳香醛或酮进行脱氧卤化，但该方法对脂肪醛无效。此外，氯化溶剂的使用不能满足日益增长的友好环境的要求。因此需要更经济的催化剂和新的环保溶剂。在此我们报告 FeCl，

  DOI：

  10.1080/00304940709458597

文献信息

• 3-Isoxazolylphenyl compounds, their preparation and their use
  申请人：BASF Aktiengesellschaft

  公开号：US05256666A1

  公开（公告）日：1993-10-26

  3-Isoxazolylphenyl compounds Ia and Ib ##STR1## where R is halogen; alkyl; haloalkyl; alkoxy; haloalkoxy; alkenyl; haloalkenyl; unsubstituted or substituted phenylethenyl; alkynyl; cycloalkyl; aryl; hetaryl; CO.sub.2 R.sup.6 or CONR.sup.7 R.sup.8, R.sup.6 is hydrogen, alkyl, cycloalkyl or benzyl; R.sup.7 and R.sup.8 are each hydrogen, alkyl, cycloalkyl or benzyl or, together with the nitrogen atom to which they are bonded, form a heterocyclic radical; n is 0, 1 or 2; R.sup.1 is halogen or alkyl; R.sup.2 is hydrogen; alkyl; alkenyl; alkynyl or cyano; R.sup.3 and R.sup.4 independently of one another are each unsubstituted or substituted alkyl, alkenyl, cycloalkyl, phenyl, naphthyl, pyridyl or pyrimidinyl; or R.sup.3 and R.sup.4 together form unsubstituted or substituted alkylene; R.sup.5 is hydrogen; unsubstituted or substituted alkyl or one of the groups stated for R.sup.3 ; X is CH.sub.2, O, S or NR.sup.9 and R.sup.9 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl or unsubstituted or substituted benzyl, processes for their preparation, agents containing them and the use thereof.

  3-异噁唑基苯化合物Ia和Ib，其中R是卤素；烷基；卤代烷基；烷氧基；卤代烷氧基；烯基；卤代烯基；未取代或取代苯乙烯基；炔基；环烷基；芳基；杂芳基；CO.sub.2 R.sup.6或CONR.sup.7R.sup.8，R.sup.6是氢、烷基、环烷基或苄基；R.sup.7和R.sup.8分别是氢、烷基、环烷基或苄基，或者与它们结合的氮原子一起形成杂环基；n为0、1或2；R.sup.1是卤素或烷基；R.sup.2是氢；烷基；烯基；炔基或氰基；R.sup.3和R.sup.4彼此独立地是未取代或取代的烷基、烯基、环烷基、苯基、萘基、吡啶基或嘧啶基；或者R.sup.3和R.sup.4一起形成未取代或取代的烷基烯基；R.sup.5是氢；未取代或取代的烷基或R.sup.3所述的基之一；X是CH.sub.2、O、S或NR.sup.9，R.sup.9是氢、烷基、环烷基、烯基、炔基或未取代或取代的苄基，其制备方法，含有它们的试剂以及其用途。
• 2-Substituted-1,3-butadiene derivatives and process for producing same
  申请人：Nissan Chemical Industries, Ltd.

  公开号：US04677216A1

  公开（公告）日：1987-06-30

  A novel 2-substituted-1,3-butadiene compound which may be used as a coupling agent is disclosed, i.e. a 2-substituted-1,3-butadiene compound of the general formula (I) ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 independently represent a halogen, a lower alkyl group, or a lower alkoxy group with the exception of those compounds wherein R.sup.1, R.sup.2 and R.sup.3 are all lower alkyl groups.

  一种可能用作偶联剂的2-取代-1,3-丁二烯化合物被公开，即具有通用公式(I)的2-取代-1,3-丁二烯化合物 除外那些R.sup.1，R.sup.2和R.sup.3都是低级烷基团的化合物。
• Process for the preparation of arylalkylmethylsilanes
  申请人：Hoechst Aktiengesellschaft

  公开号：US05124470A1

  公开（公告）日：1992-06-23

  The present invention relates to a process for the preparation of arylalkylmethylsilanes of the formula I ##STR1## where X is CH.dbd.CH, N.dbd.CH, CH.dbd.N or S, R.sup.1 and R.sup.2 independently of one another are H, halogen, (C.sub.1 to C.sub.4)alkyl, (C.sub.1 to C.sub.4)alkoxy, (C.sub.1 to C.sub.4)alkylthio, (C.sub.1 to C.sub.4)haloalkyl, (C.sub.1 to C.sub.4)haloalkoxy or (C.sub.1 to C.sub.4)haloalkylthio, R.sup.3 is (C.sub.1 to C.sub.6)alkyl and m and n are 0, 1 or 2, which comprises reacting dichloromethylsilane II ##STR2## first with an arylmagnesium halide of the formula III ##STR3## where R.sup.1, R.sup.2, m, n and X are as defined in Formula I and Hal is halogen, at temperatures of from -78.degree. to 0.degree. C., and subsequently with an alkylmagnesium halide of the formula IV R.sup.3 --Mg Hal (IV), where R.sup.3 is as defined in formula I and Hal is halogen, if appropriate in the presence of a solvent.

  本发明涉及一种制备芳基烷基甲基硅烷的方法，其化学式为I，其中X为CH.dbd.CH，N.dbd.CH，CH.dbd.N或S，R.sup.1和R.sup.2彼此独立地为H，卤素，(C.sub.1到C.sub.4)烷基，(C.sub.1到C.sub.4)烷氧基，(C.sub.1到C.sub.4)烷硫基，(C.sub.1到C.sub.4)卤代烷基，(C.sub.1到C.sub.4)卤代烷氧基或(C.sub.1到C.sub.4)卤代烷硫基，R.sup.3为(C.sub.1到C.sub.6)烷基，m和n为0、1或2。该方法包括首先将二氯甲基硅烷II与化学式III的芳基镁卤化物反应，其中R.sup.1、R.sup.2、m、n和X如化学式I中定义，Hal为卤素，在-78°C至0°C的温度下进行，然后再与化学式IV的烷基镁卤化物反应，其中R.sup.3如化学式I中定义，Hal为卤素，必要时在溶剂存在下进行。
• Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof
  申请人：Jun Chul-Ho

  公开号：US20090274910A1

  公开（公告）日：2009-11-05

  Disclosed are a protected alcohol or derivative thereof, a surface-modified organic-inorganic hybrid glass, and preparation methods thereof. More specifically, disclosed are a protected alcohol or derivative thereof and a surface-modified organic-inorganic hybrid glass, which are prepared by allowing a silane compound, having vinyl or a vinyl derivative, to react with an alcohol or derivative thereof or with an organic-inorganic hybrid glass, in the presence of an acid catalyst, a transition metal catalyst and an organic solvent, so as to introduce an organic group thereto even at room temperature, as well as preparation methods thereof. The disclosed invention allows a functional group to be effectively introduced into alcohol or a derivative thereof or into an organic-inorganic hybrid glass, not only high temperatures but also room temperature, and thus is highly effective in introducing compounds having a thermally sensitive functional group, for example, natural compounds or proteins. Also, the invention makes it possible to introduce various organic groups and to separate and purify organic macromolecule-bonded organosilane compounds using a silica gel column so as to effectively introduce large organic functional groups to inorganic materials. Accordingly, the invention is highly useful in the chemical industry.

  本文揭示了一种受保护的醇或其衍生物、一种表面改性的有机-无机混合玻璃及其制备方法。更具体地，本文揭示了一种受保护的醇或其衍生物以及一种表面改性的有机-无机混合玻璃，通过让具有乙烯或乙烯衍生物的硅烷化合物在酸催化剂、过渡金属催化剂和有机溶剂的存在下与醇或其衍生物或有机-无机混合玻璃发生反应，从而在室温下引入有机基团，以及其制备方法。本发明允许在醇或其衍生物或有机-无机混合玻璃中有效引入功能基团，不仅在高温下，而且在室温下，因此在引入具有热敏功能基团的化合物方面非常有效，例如天然化合物或蛋白质。此外，该发明使得可以引入各种有机基团，并且利用硅胶柱分离和纯化有机大分子结合的有机硅烷化合物，从而有效地将大有机功能基团引入无机材料中。因此，该发明在化学工业中具有非常高的实用性。
• Silylated cyclic hydrocarbons and their uses
  申请人：OSi Specialties, Inc.

  公开号：US05514827A1

  公开（公告）日：1996-05-07

  This invention includes di- and tri(alkoxysilylalkyl)- or haloalkoxysilylalkylcyclic pentanes, which may have substituents thereon, including vinyl groups, and their use as waterproofing agents, as crosslinking agents in room temperature vulcanizing silicone caulks, in coating compositions and as surface treatments. The cyclic hydrocarbons are pentane (C.sub.s). The silane groups are attached to the ring through an alkyl group, which may have substituents thereon. Multiple silane groups may be attached to the ring. The silanes may have the standard substituents thereon, including alkoxy and halogens. The specific silanes contemplated herein have the following formula: R.sub.a X.sub.3-a Si(CR'.sub.2).sub.n !.sub.b cycloC.sub.5 R".sub.10-b where R is an alkyl or aryl group, X is a halogen or an alkoxy radical of 1 to 4 carbon atoms, aryloxy radical or oxime group, R' is a hydrogen or alkyl group of 1 to 3 carbon atoms, R" is a vinyl, alkyl, allyl, aryl, aryloxy or alkoxy group or hydrogen, a=0, 1 or 2, n=2 to 3 and if at least one R" is a vinyl or allyl group, b=1 to 5, otherwise b=2 to 5.

  该发明包括二(烷氧基硅烷烷基)或三(烷氧基硅烷烷基)环戊烷，可能在其上有取代基，包括乙烯基，并且它们作为防水剂、在室温硫化硅密封胶中的交联剂、在涂料组合物中以及作为表面处理剂的用途。这些环烃是戊烷(C.sub.s)。硅烷基通过烷基连接到环上，该烷基可能在其上有取代基。多个硅烷基可以连接到环上。硅烷可能具有标准的取代基，包括烷氧基和卤素。在此考虑的具体硅烷具有以下公式：R.sub.a X.sub.3-a Si(CR'.sub.2).sub.n !.sub.b cycloC.sub.5 R".sub.10-b，其中R是烷基或芳基，X是1至4个碳原子的卤素或烷氧基基团、芳基氧基基团或肟基团，R'是1至3个碳原子的氢或烷基基团，R"是乙烯基、烷基、烯丙基、芳基、芳基氧基或烷氧基或氢，a=0、1或2，n=2至3，如果至少一个R"是乙烯基或烯丙基，则b=1至5，否则b=2至5。