2-(3-(furan-2-yl)-6-oxo-6H-xanthen-9-yl)benzoic acid | 1398063-76-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-(3-(furan-2-yl)-6-oxo-6H-xanthen-9-yl)benzoic acid
• 英文别名: 2-[3-(Furan-2-yl)-6-oxoxanthen-9-yl]benzoic acid；2-[3-(furan-2-yl)-6-oxoxanthen-9-yl]benzoic acid
• CAS: 1398063-76-7
• 化学式: C₂₄H₁₄O₅
• 分子量: 382.372
• InChiKey: WPZPLNKCZHJVQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  76.7
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  fluorescein free acid 在 palladium diacetate 、 potassium carbonate 、 三苯基膦 作用下， 以 1,4-二氧六环 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 生成 2-(3-(furan-2-yl)-6-oxo-6H-xanthen-9-yl)benzoic acid
  参考文献：
  名称：

  A highly sensitive fluorescent viscosity sensor

  摘要：

  Variation at the 3' position of fluorescein via Suzuki-Miyaura cross-coupling with aryl and heteroaryl moieties gave a family of anthofluoresceins whose spectroscopic properties were studied. The 1-methylindole derivative gave the highest quantum yield and was observed to behave as a molecular rotor, displaying marked variations in fluorescent intensities with viscosity and offering possible application in cellular sensing and fluorescent polarisation assays. (c) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.07.101

文献信息

• A highly sensitive fluorescent viscosity sensor
  作者：Rahimi M. Yusop、Asier Unciti-Broceta、Mark Bradley

  DOI：10.1016/j.bmcl.2012.07.101

  日期：2012.9

  Variation at the 3' position of fluorescein via Suzuki-Miyaura cross-coupling with aryl and heteroaryl moieties gave a family of anthofluoresceins whose spectroscopic properties were studied. The 1-methylindole derivative gave the highest quantum yield and was observed to behave as a molecular rotor, displaying marked variations in fluorescent intensities with viscosity and offering possible application in cellular sensing and fluorescent polarisation assays. (c) 2012 Elsevier Ltd. All rights reserved.