2-氯-6-(4-甲烷磺酰基-哌嗪-1-甲基)-4-吗啉-4-基-噻吩并[3,2-D]嘧啶 | 885675-66-1

分子结构分类

有机化合物 - 有机杂环化合物 - 噻吩并嘧啶酮衍生物

中文名称

2-氯-6-(4-甲烷磺酰基-哌嗪-1-甲基)-4-吗啉-4-基-噻吩并[3,2-D]嘧啶

中文别名

——

英文名称

4-(2-chloro-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine

英文别名

4-[2-chloro-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine

2-氯-6-(4-甲烷磺酰基-哌嗪-1-甲基)-4-吗啉-4-基-噻吩并[3,2-D]嘧啶化学式

CAS

885675-66-1

化学式

C₁₆H₂₂ClN₅O₃S₂

mdl

——

分子量

431.967

InChiKey

FELGNOOJSGQIPV-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.53±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

1.3
重原子数：

27
可旋转键数：

4
环数：

4.0
sp3杂化的碳原子比例：

0.62
拓扑面积：

116
氢给体数：

0
氢受体数：

9

安全信息

海关编码：

2934999090

SDS

SDS：e4052254eee3b9739f6888bfda15b6c4

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上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
2-氯-4-(4-吗啉)噻吩并[3,2-d]嘧啶-6-甲醇	(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methanol	885698-97-5	C₁₁H₁₂ClN₃O₂S	285.754
——	4-(2-chloro-6-(chloromethyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1381841-06-0	C₁₁H₁₁Cl₂N₃OS	304.2
2-氯-4-(4-吗啉)-噻吩并[3,2-d]嘧啶-6-羧醛	2-chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde	885618-31-5	C₁₁H₁₀ClN₃O₂S	283.738
2-氯-4-(4-吗啉基)噻吩并[3,2-D]嘧啶	2-chloro-4-morpholinothieno[3,2-d]pyrimidine	16234-15-4	C₁₀H₁₀ClN₃OS	255.728

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	4-(2-hydrazinyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1381841-07-1	C₁₆H₂₅N₇O₃S₂	427.552
——	6-(4-methanesulfonyl-piperazin-1-ylmethyl)-2-methylsulfanyl-4-morpholin-4-yl-thieno[3,2-d]pyrimidine	956034-76-7	C₁₇H₂₅N₅O₃S₃	443.615
——	4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-2-phenylthieno[3,2-d]pyrimidin-4-yl)morpholine	1204033-28-2	C₂₂H₂₇N₅O₃S₂	473.62
——	6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine	1032755-24-0	C₂₁H₂₆N₆O₃S₂	474.608
——	5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine	1032755-16-0	C₂₀H₂₆N₈O₃S₂	490.61
——	4-[6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-2-yl]-phenylamine	1204033-31-7	C₂₂H₂₈N₆O₃S₂	488.635
——	5-[6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamine	1032755-38-6	C₂₁H₂₇N₇O₃S₂	489.622
——	(3-(6-((4-(methanesulfonyl)piperazin-1-yl)methyl)-4-morpholino-thieno[3,2-d]pyrimidin-2-yl)phenyl)methanol	956032-81-8	C₂₃H₂₉N₅O₄S₂	503.646
——	(E)-4-((2-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)hydrazono)methyl)benzonitrile	1394047-56-3	C₂₄H₂₈N₈O₃S₂	540.67
——	4-morpholino-6-((4-N-methylsulfonylpiperazin-1-yl)methyl)-2-(thiazol-5-yl)thieno[3,2-d]pyrimidine	1032754-36-1	C₁₉H₂₄N₆O₃S₃	480.636
——	5-(4-morpholino-6-((4-N-methylsulfonylpiperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-2-yl)pyridin-2-ol	1032754-79-2	C₂₁H₂₆N₆O₄S₂	490.607
2-氯-4-(4-吗啉)-噻吩并[3,2-d]嘧啶-6-羧醛	2-chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde	885618-31-5	C₁₁H₁₀ClN₃O₂S	283.738
——	5-[6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-2-yl]-4-methyl-pyrimidin-2-ylamine	1032756-86-7	C₂₁H₂₈N₈O₃S₂	504.637
——	(E)-4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-2-(2-(4-(trifluoromethoxy)benzylidene)hydrazinyl)thieno[3,2-d]-pyrimidin-4-yl)morpholine	1394047-53-0	C₂₄H₂₈F₃N₇O₄S₂	599.658
——	(E)-4-(2-(2-(2-chloro-4-fluorobenzylidene)hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]-pyrimidin-4-yl)morpholine	1394047-55-2	C₂₃H₂₇ClFN₇O₃S₂	568.096
——	(E)-4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-2-(2-(3,4,5-trimethoxybenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-46-1	C₂₆H₃₅N₇O₆S₂	605.739
——	4-(2-(1H-indol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)-methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	885675-45-6	C₂₄H₂₈N₆O₃S₂	512.657
——	(E)-4-(2-(2-(benzo[d][1,3]dioxol-5-ylmethylene)hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-52-9	C₂₄H₂₉N₇O₅S₂	559.67
4-羟基-2,6-二甲基苯甲腈	pictilisib	957054-30-7	C₂₃H₂₇N₇O₃S₂	513.644
——	(E)-4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-2-(2-(2,3,4-trimethoxybenzylidene)hydrazinyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-47-2	C₂₆H₃₅N₇O₆S₂	605.739
——	4-(2-(2-ethyl-1H-benzo[d]imidazol-1-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1381878-39-2	C₂₅H₃₁N₇O₃S₂	541.698
——	(E)-4-(2-(2-((1-benzyl-1H-benzo[d]imidazol-2-yl)methylene)hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl) methyl)-thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-73-4	C₃₁H₃₅N₉O₃S₂	645.809
——	(E)-4-(2-(2-((1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)methylene)hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-70-1	C₃₂H₃₇N₉O₃S₂	659.836
——	(E)-4-(2-(2-((1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)methylene)hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-74-5	C₃₁H₃₄ClN₉O₃S₂	680.254
——	ethyl 5-(4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)-2H-indazol-2-yl)pentanoate	1235450-09-5	C₃₀H₃₉N₇O₅S₂	641.816
——	ethyl 6-(4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)-2H-indazol-2-yl)hexanoate	1235450-11-9	C₃₁H₄₁N₇O₅S₂	655.842
——	ethyl 3-(4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)-1H-indazol-1-yl)propanoate	1339922-65-4	C₂₈H₃₅N₇O₅S₂	613.762
——	(E)-4-(2-(2-((1-benzyl-1H-indol-3-yl)methylene)hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-66-5	C₃₂H₃₆N₈O₃S₂	644.822
——	(E)-4-(2-(2-((1-(3-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)methylene) hydrazinyl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine	1394047-75-6	C₃₁H₃₄ClN₉O₃S₂	680.254
——	ethyl 5-(4-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)-1H-indazole-1-yl)pentanoate	1235450-10-8	C₃₀H₃₉N₇O₅S₂	641.816