(+)-3,11-dioxo-5α-androstanecarboxylic acid | 74356-15-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (+)-3,11-dioxo-5α-androstanecarboxylic acid
• 英文别名: 3,11-dioxo-21-nor-5α-pregnanoic acid-(20)；3.11-Dioxo-5α-androstan-carbonsaeure-(17β)；3,11-Dioxo-21-nor-5α-pregnansaeure-(20)；(+)-3,11-Dioxo-5alpha-androstanecarboxylic acid；(5S,8S,9S,10S,13S,14S,17S)-10,13-dimethyl-3,11-dioxo-2,4,5,6,7,8,9,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid
• CAS: 74356-15-3
• 化学式: C₂₀H₂₈O₄
• 分子量: 332.44
• InChiKey: PZEAAKYUPNNSNT-ADOJBAKHSA-N

物化性质

• 熔点：
  286 °C (decomp)(Solvent: Ethyl acetate)
• 沸点：
  504.0±50.0 °C(predicted)
• 密度：
  1.189±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  71.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 (+)-3,11-dioxo-5α-androstanecarboxylic acid 在 乙醚 作用下， 生成 3,11-dioxo-5α-androstane-17β-carboxylic acid methyl ester
  参考文献：
  名称：

  关于肾上腺皮质的成分。21.沟通。物质R和S的组成

  摘要：

  DOI：

  10.1002/hlca.193802101183
• 作为产物：
  描述：

  肾上腺酮 在 potassium dichromate 、 乙醇 、 硫酸 、 钯 、 过碘酸 、 丙酮 作用下， 生成 (+)-3,11-dioxo-5α-androstanecarboxylic acid
  参考文献：
  名称：

  Behavioural observations of interactions in a free-ranging lynxLynx lynx family at kills

  摘要：

  The behaviour of a free-ranging female lynx Lynx lynx Linnaeus, 1758 and her kittens at 12 different kills was studied for 44 hours of observation from September 1996 to March 1997. The development of interactions at kills of a lynx family group showed the following pattern: until the end of September we often observed two lynx, usually both kittens, food from the kill at the same time. After the age of four months aggression between kittens was observed frequently, with the bigger kitten being dominant. From September the kittens were never again seen feeding together at the kill, However, we never observed fighting, and aggressive behaviour did not increase with the age of the, kittens. Whereas until December one of the kittens was always first at the kill, from January onwards it was mostly the adult female who ate first. She introduced her kittens to the home range of a neighbouring female where the family break-up occurred. The kittens were last seen together with their mother on 26 March. Dispersal seemed to be initiated by the female abandoning the kittens.

  DOI：

  10.1007/bf03192451

文献信息

• Polymer Nanocomposites: Status and Opportunities
  作者：Richard A. Vaia、Emmanuel P. Giannelis

  DOI：10.1557/mrs2001.93

  日期：2001.5

  Reinforcement of polymers with a second phase, whether inorganic or organic, to produce a polymer composite is common in the production of modern plastics. Polymer nanocomposites (PNCs) represent a radical alternative to these conventional polymer composites.

  将聚合物与第二相（不论是无机的还是有机的）强化，以生产聚合物复合材料，在现代塑料生产中很常见。聚合物纳米复合材料（PNCs）代表了这些传统聚合物复合材料的一种激进替代方案。