4-chloro-2-(cyclopropyliminomethyl)phenol | 1577254-47-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-chloro-2-(cyclopropyliminomethyl)phenol
• CAS: 1577254-47-7
• 化学式: C₁₀H₁₀ClNO
• 分子量: 195.648
• InChiKey: HQNUBQXBUIJTHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.63
• 重原子数：
  13.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  32.59
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  4-chloro-2-(cyclopropyliminomethyl)phenol 、 zinc(II) acetate dihydrate 以 乙醇 为溶剂， 反应 2.0h， 以73%的产率得到Zn(4-chloro-2-(cyclopropyliminomethyl)phenolate)2
  参考文献：
  名称：

  Preparation, X-Ray Structures, and Cytotoxic Property of Mononuclear Schiff Base Zinc Complexes [Zn(SalPr)₂] and [ZnI₂(SalPt)₂]

  摘要：

  Schiff bases obtained from 5-chlorosalicylaldehyde with cyclopropylamine, and 4-methoxysalicylaldehyde with cyclopentylamine, were used as ligands for Zn(II) resulting in two mononuclear zinc complexes, [Zn(SalPr)(2)] and [ZnI2(SalPt)(2)], where SalPr is 4-chloro-2-(cyclopropyliminomethyl)phenolate and SalPt is 2-(cyclopentyliminiummethyl)-5-methoxyphenolate. The detailed structures of the complexes were determined by single crystal X-ray crystallography. Coordination sphere of Zn(II) atoms in both complexes are slightly distorted tetrahedron. The cytotoxic property of the complexes was evaluated.

  DOI：

  10.1080/15533174.2013.770763