碘酸 | 7782-68-5

• 物质功能分类: 无机化工 - 无机酸
• 分子结构分类: 无机化合物 - 均质非金属化合物 - 非金属氧阴离子化合物
• 中文名称: 碘酸
• 英文名称: iodic acid
• 英文别名: HIO₃；Hydron;iodate；hydron;iodate
• CAS: 7782-68-5
• 化学式: HIO₃
• 分子量: 175.911
• InChiKey: ICIWUVCWSCSTAQ-UHFFFAOYSA-N

物化性质

• 熔点：
  110°C (dec.)
• 密度：
  4.63 g/cm3
• 溶解度：
  可微溶于水
• 稳定性/保质期：

  1. 稳定性：稳定。

  2. 禁配物：强还原剂、醇类、易燃或可燃物、硫、磷、有机物。

  3. 避免接触的条件：光照。

  4. 聚合危害：不聚合。

  5. 分解产物：碘化物。

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  4
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

ADMET

毒理性

• 副作用

Dermatotoxin - 皮肤烧伤。

Dermatotoxin - Skin burns.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

安全信息

• TSCA：
  Yes
• 危险等级：
  5.1
• 危险品标志：
  C
• 安全说明：
  S17,S26,S36/37/39,S45
• 危险类别码：
  R8,R34
• WGK Germany：
  3
• 海关编码：
  28111980
• 危险品运输编号：
  UN 3085
• 危险类别：
  5.1
• 包装等级：
  II
• 危险标志：
  GHS03,GHS05
• 危险性描述：
  H272,H314
• 危险性防范说明：
  P220,P280,P305 + P351 + P338,P310
• 储存条件：
  储存注意事项：应将储存于阴凉、通风的库房中，并远离火种和热源。库房温度不得超过30℃，相对湿度不超过80%。避免直接光照，包装需密封保存。建议与还原剂、醇类以及易（可）燃物分开存放，切忌混储。同时，在储存区应准备合适的材料以处理可能的泄漏情况。

SDS

Name:	Iodic Acid Material Safety Data Sheet
Synonym:	Hydrogen Iodat
CAS:	7782-68-5

Section 1 - Chemical Product MSDS Name:Iodic Acid Material Safety Data Sheet
Synonym:Hydrogen Iodat

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
7782-68-5	Iodic Acid	>99.5	231-962-1

Hazard Symbols: O C
Risk Phrases: 34 8

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns. Contact with combustible material may cause fire.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May cause permanent corneal opacification. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects. May cause nausea, vomiting, and diarrhea, possibly with blood.
Inhalation:
Causes chemical burns to the respiratory tract. May cause systemic effects. May cause acute pulmonary edema, asphyxia, chemical pneumonitis, and upper airway obstruction caused by edema.
Chronic:
Effects may be delayed.

---

Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Strong oxidizer. Contact with other material may cause fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible. Use water with caution and in flooding amounts.
Oxidizer. Greatly increases the burning rate of combustible materials.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Contact professional fire-fighters immediately.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid contact with clothing and other combustible materials. Avoid ingestion and inhalation. Use with adequate ventilation. Discard contaminated shoes.
Storage:
Keep away from heat, sparks, and flame. Do not store near combustible materials. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 7782-68-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white to pale yellow
Odor: none reported
pH: Acidic in solution.
Vapor Pressure: Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 230 deg F
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 230 deg F
Solubility in water: 2.8 kg/L H2O @ 0C
Specific Gravity/Density: 4.629 (water=1)
Molecular Formula: HIO3
Molecular Weight: 175.9097

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, ignition sources, dust generation, combustible materials, reducing agents.
Incompatibilities with Other Materials:
Reducing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, iodine.
Hazardous Polymerization: Has not been reported.

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7782-68-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Iodic Acid - Not listed by ACGIH, IARC, or NTP.

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

---

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: OXIDIZING SOLID, NOS
Hazard Class: 5.1
UN Number: 1479
Packing Group: II
IMO
Shipping Name: OXIDIZING SOLID, NOS
Hazard Class: 5.1
UN Number: 1479
Packing Group: II
RID/ADR
Shipping Name: OXIDIZING SOLID, NOS
Hazard Class: 5.1
UN Number: 1479
Packing group: II

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: O C
Risk Phrases:
R 34 Causes burns.
R 8 Contact with combustible material may cause
fire.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...
WGK (Water Danger/Protection)
CAS# 7782-68-5: 1
Canada
CAS# 7782-68-5 is listed on Canada's DSL List.
CAS# 7782-68-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7782-68-5 is listed on the TSCA inventory.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

用途
用作分析试剂，并广泛应用于制药和有机合成。
用途
用作分析试剂，制造药物等。

反应信息

• 作为反应物：
  描述：

  碘酸 在 H₂S₄O₆ 作用下， 以 水 为溶剂， 生成 氢碘酸
  参考文献：
  名称：

  Casolari, A., Gazzetta Chimica Italiana, 1907, vol. 37, p. 615 - 615

  摘要：

  DOI：
• 作为产物：
  描述：

  碘 在 hypochloric acid 作用下， 以 not given 为溶剂， 生成 碘酸
  参考文献：
  名称：

  Balard, A. J., Annales de Chimie et de Physique, 1834, vol. 57, p. 301 - 301

  摘要：

  DOI：
• 作为试剂：
  描述：

  在 碘 、 碘酸 作用下， 以 乙醇 、 水 为溶剂， 以30 %的产率得到
  参考文献：
  名称：

  10.1002/cmdc.202400187

  摘要：

  AbstractA series of naphtho[1,8‐ef]isoindole‐7,8,10(9H)‐trione derivatives as novel theranostic agents for photodynamic therapy and multi‐subcellular organelles localization were designed and synthesized. Most of them possess moderate fluorescence quantum yield and long wavelength absorption simultaneously, which made them possible for dual effects of imaging and therapy. Notably, compounds 7 b and 7 d exhibited significant light‐toxicity but slight dark‐toxicity. Confocal fluorescence microscopy experiments demonstrated that compound 7 b can locate and image in special multi‐subcellular organelles. All the research results implied that naphtho[1,8‐ef] isoindole‐7,8,10(9H)‐trione derivatives can be applied as a new series of theranostic agents with the characteristics of photodynamic therapy and multi‐subcellular organelles imaging.

  DOI：

  10.1002/cmdc.202400187

文献信息

• Mixed-Metal Uranium(VI) Iodates:  Hydrothermal Syntheses, Structures, and Reactivity of Rb[UO₂(CrO₄)(IO₃)(H₂O)], A₂[UO₂(CrO₄)(IO₃)₂] (A = K, Rb, Cs), and K₂[UO₂(MoO₄)(IO₃)₂]
  作者：Richard E. Sykora、Steven M. McDaniel、Daniel M. Wells、Thomas E. Albrecht-Schmitt

  DOI：10.1021/ic025773y

  日期：2002.10.1

  iodates A[CrO(3)(IO(3))] (A = K, Rb, Cs) with UO(3) under mild hydrothermal conditions provide access to four new, one-dimensional, uranyl chromatoiodates, Rb[UO(2)(CrO(4))(IO(3))(H(2)O)] (1) and A(2)[UO(2)(CrO(4))(IO(3))(2)] (A = K (2), Rb (3), Cs (4)). Under basic conditions, MoO(3), UO(3), and KIO(4) can be reacted to form K(2)[UO(2)(MoO(4))(IO(3))(2)] (5), which is isostructural with 2 and 3. The structure

  分子过渡金属碘酸盐A [CrO（3）（IO（3））]（A = K，Rb，Cs）与UO（3）在温和的热液条件下的反应提供了对四个新的一维铀酰的访问铬酸盐，Rb [UO（2）（CrO（4））（IO（3））（H（2）O）]（1）和A（2）[UO（2）（CrO（4））（IO（ 3））（2）]（A = K（2），Rb（3），Cs（4））。在基本条件下，MoO（3），UO（3）和KIO（4）可以反应形成K（2）[UO（2）（MoO（4））（IO（3））（2）]（ 5），它与2和3等构。1的结构由一维[UO（2）（CrO（4））（IO（3））（H（2）O）]（-）条带组成包含通过桥接铬酸根和碘酸根阴离子以及末端水分子在U（VI）中心周围创建[UO（7）]五边形双锥体环境的铀酰部分。这些带被Rb（+）阳离子彼此隔开。当水热反应中碘酸盐含量增加时，末端水分子被单齿碘酸根阴离子取代，生成2-4。可以通过用Mo
• A ratiometric near-infrared pH-responsive fluorescent dye based on distyryl BODIPY
  作者：Hui He、Dennis K. P. Ng

  DOI：10.1039/c0ob01252a

  日期：——

  A novel distyryl boron dipyrromethene substituted with two 4-(dimethylamino)phenylethynyl groups at the 2- and 6-positions has been synthesised and characterised. It exhibits remarkable and reversible pH-responsive changes in the absorption and fluorescence emission spectra, both in organic and in aqueous media.

  合成并表征了新颖的二苯乙烯基硼二吡咯亚甲基，其在2-和6-位被两个4-（二甲基氨基）苯基乙炔基取代。在有机介质和水性介质中，它在吸收和荧光发射光谱中均表现出显着且可逆的pH响应变化。
• Expansion of the structural diversity of f-element bearing molybdate iodates: synthesis, structures, and optical properties
  作者：Jian Lin、Qi Liu、Zenghui Yue、Kariem Diefenbach、Liwei Cheng、Yuejian Lin、Jian-Qiang Wang

  DOI：10.1039/c8dt05120h

  日期：——

  compositions and structures is clearly observed, showing the increase in hydration from the early to late lanthanide analogues and the decrease in unit cell dimensions and the average Ln–O bonding distances across the same structure type. Single crystal X-ray diffraction studies reveal that LnMoIO-1 (Ln = Ce and Pr) crystalize in a noncentrosymmetric space group P21 and the second-harmonic generation

  通过水热反应扩大含f元素的碘酸钼酸碘盐家族，已生产出十种新的稀土钼酸碘酸盐，它们具有两个不同的相，即Ln（MOO 2）（IO 3）4（OH）（LnMOIO-1，Ln = Ce和Pr ）和Ln（MO 2 O 7）（IO 3）（H 2 O）2（LnMOIO-2，Ln = Gd–Yb和Y），以及第一钼酸MO碘酸盐ThF（MO 4）（IO 3）（ThFMa href=https://www.molaid.com/MS_187332 target="_blank">MOIO）。所有这三个结构均显示三维框架，并且仅由钼酸盐和碘酸盐桥接的镧系/ act系多面体构建。此外，钼酸盐的配位通用性（八面体，方形锥体和四面体几何形状）导致结构的多样性。可以清楚地观察到镧系元素收缩对组成和结构的影响，表明从早期到晚期镧系元素类似物的水合作用增加，并且在相同结构类型上单位晶胞尺寸和平均Ln–O键距减小。单晶X射线衍射研究表明LnMOIO-1（Ln = Ce和Pr）在非中心对称空间群P 2 1中结晶次谐波生成（SHG）测量显示PrMOIO-1的响应为5×KDP
• Assisting the Effective Design of Polar Iodates with Early Transition-Metal Oxide Fluoride Anions
  作者：Hongwei Yu、Matthew L. Nisbet、Kenneth R. Poeppelmeier

  DOI：10.1021/jacs.8b04762

  日期：2018.7.18

  α- and β-Ba[VFO2(IO3)2] contain the trans-[VFO2(IO3)2]2- polyanion and crystallize in the nonpolar space groups Pbcn and P212121. In contrast, α- and β-Ba2[VO2F2(IO3)2]IO3 contain the cis-[VO2F2(IO3)2]3- Λ-shaped polyanion and crystallize in the polar space groups Pna21 and P21, respectively. Detailed structural analyses show that the variable polar orientation of trans-[VFO2(IO3)2]2- polyanions is

  极性材料具有重要的技术意义，但难以有效合成。对于碘酸盐尤其如此，碘酸盐是一类重要的可见光和中红外透明非线性光学 (NLO) 材料。针对极性碘酸盐的新设计策略，我们成功合成了两组多晶型早期过渡金属（ETM）氧化物-氟化物碘酸盐，α-和β-Ba[VFO2(IO3)2]和α-和β-Ba2 [VO2F2( )2] ，基于氧化物-氟化物阴离子独特的结构导向特性。α- 和 β-Ba[VFO2( )2] 包含反式-[VFO2( )2]2- 聚阴离子并在非极性空间群 Pbcn 和 P212121 中结晶。相比之下，α-和β-Ba2[VO2F2( )2] 包含顺式-[VO2F2( )2]3-Λ 型聚阴离子并分别在极性空间群 Pna21 和 P21 中结晶。详细的结构分析表明反式-[VFO2( )2]2-聚阴离子的可变极性取向是α-和β-Ba[VFO2( )2]中非极性结
• ABi₂ (IO₃ )₂ F₅ (A=K, Rb, and Cs): A Combination of Halide and Oxide Anionic Units To Create a Large Second-Harmonic Generation Response with a Wide Bandgap
  作者：Hongming Liu、Qi Wu、Xingxing Jiang、Zheshuai Lin、Xianggao Meng、Xingguo Chen、Jingui Qin

  DOI：10.1002/anie.201705672

  日期：2017.8.1

  ABi2(IO3)2F5 (A=K (1), Rb (2), and Cs (3)), have been designed and synthesized. They crystallize in the same polar space group (P21) with a two‐dimensional double‐layered framework constructed by [BiF5]2− and [BiO2F4]5− units connected to each other by four F atoms, in which two [IO3]− groups are linked to [BiO2F4]5− unit on the same side. A hanging Bi−F bond of [BiF5]2− unit is located on the other

  一类非线性光学材料，在单个结构中同时包含卤化物，氧化物和卤氧化物极性单元，即ABi 2（IO 3）2 F 5（A = K（1），Rb（2）和Cs（3）），已经过设计和合成。它们在由[BiF 5 ] 2−和[BiO 2 F 4 ] 5−单元通过四个F原子相互连接构成的二维双层框架中，在同一极性空间群（P 2 1）中结晶。哪两个[IO 3 ] -基团在同一侧链接到[BiO 2 F 4 ] 5−单元。[BiF 5 ] 2−单元的悬垂Bi-F键通过与插入层的碱金属离子的离子相互作用而位于另一侧，从而形成三维结构。在1064 nm激光辐射下，这些极性单元的有序排列导致非常强的二次谐波生成响应，分别是磷酸二氢钾的12（1），9.5（2）和7.5（3）倍。它们都显示出超过3.75 eV的宽能带隙，表明它们将具有较高的激光损伤阈值。

表征谱图