bis(2-(N,N-diethylamino)ethyl)sulfide | 6006-58-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: bis(2-(N,N-diethylamino)ethyl)sulfide
• 英文别名: bis(2-diethylaminoethyl) sulfide；2-Diethylaminoethyl-sulfid；Bis-(N,N-Diethyl-2-aminoethyl)-sulfid；Di-(2-diethylaminoethyl)-sulfid；β,β'-Bis-diaethylamino-diaethylsulfid；Bis-(β-diaethylamino-aethyl)-sulfid；2.2'-Bis-diaethylamino-diaethylsulfid；Bis-(2-diaethylamino-aethyl)-sulfid；2-[2-(diethylamino)ethylsulfanyl]-N,N-diethylethanamine
• CAS: 6006-58-2
• 化学式: C₁₂H₂₈N₂S
• 分子量: 232.434
• InChiKey: LYFNBXZVKYDWNX-UHFFFAOYSA-N

物化性质

• 沸点：
  64 °C(Press: 0.4 Torr)
• 密度：
  0.8950 g/cm3
• 溶解度：
  0.00 M
• 保留指数：
  1579;1584

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  31.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(2-(N,N-diethylamino)ethyl)sulfide 在 potassium permanganate 、 硫酸 作用下， 生成 Di-(2-diethylaminoethyl)-sulfon
  参考文献：
  名称：

  Fakstorp, Acta Chemica Scandinavica (1947), 1956, vol. 10, p. 15,18

  摘要：

  DOI：
• 作为产物：
  描述：

  N,N-二乙基氯乙胺 在 sodium hydrogensulfide 、 乙醇 作用下， 生成 bis(2-(N,N-diethylamino)ethyl)sulfide
  参考文献：
  名称：

  M EASUREMENT OF P EDIATRIC I LLNESS S EVERITY U SING S IMPLE P RETRANSPORT V ARIABLES

  摘要：

  Objective: To test the hypothesis that pretransport variables can predict in-hospital mortality that will correlate with major interventions and unplanned events during interfacility transport. Methods: A cohort of children (n = 2,253) transported by a specialized pediatric team to a children's hospital were studied. At the time of referral, data collected included age (months), heart rate, systolic blood pressure, respiratory rate, retractions, stridor or wheezing, seizures, skin perfusion, oxygen requirement, and mental status. Using univariate and stepwise logistic regression, variables predictive of in-hospital mortality were selected from a training set (n = 1,111) and assigned integers based on their computed coefficients. Probability of in-hospital mortality was calculated using the total integer score and age. The risk of mortality derived from the training set was validated in the remaining patients (n = 1,142) by comparing the observed and predicted mortalities. Major interventions performed and unplanned events were determined for each of five predetermined mortality risk groups. Results: Variables (integers) predicting in-hospital mortality included systolic blood pressure (11), respiratory rate (6), oxygen requirement (11), and altered mental status (11). Observed mortality was similar to predicted mortality in all risk categories for the validation sample. As risk of mortality increased, so did the performance of major interventions and the occurrence of unplanned events. Conclusion: Four pretransport variables predicted in-hospital mortality. Risk of mortality correlated with the incidence of major patient interventions, and the occurrence of unplanned events increased as well. This model might be useful in comparing different transport systems using severity-adjusted assessment of children requiring interfacility transport.

  DOI：

  10.1080/10903120190939986

文献信息

• A novel approach for the detection and identification of sulfur mustard using liquid chromatography–electrospray ionization–tandem mass spectrometry based on its selective oxidation to sulfur mustard monoxide with <i>N</i> ‐iodosuccinimide
  作者：Hagit Prihed、Avital Shifrovich、Tamar Shamai Yamin、Moran Madmon、Boris Smolkin、Ravit Chen、Merav Blanca、Avi Weissberg

  DOI：10.1002/jms.4721

  日期：2021.5

  new derivatization strategy for the detection and identification of sulfur mustard (HD) via liquid chromatography–electrospray ionization–tandem mass spectrometry (LC‐ESI‐MS/MS) is developed. The method incorporates selective oxidation of the sulfide group by the electrophilic iodine reagent N‐iodosuccinimide (NIS) to produce sulfur mustard monoxide (HDSO). The derivatization reaction efficiencies were

  提出了一种通过液相色谱-电喷雾电离-串联质谱（LC-ESI-MS / MS）检测和鉴定硫芥菜（HD）的新衍生化策略。该方法结合了亲电子碘试剂N-碘代琥珀酰亚胺（NIS）对硫化物基团的选择性氧化，从而生成一氧化硫芥子油（HDSO）。用加标浓度为50-5000 pg / ml的HD的土壤，沥青，布料，Formica和油毡的乙腈提取物评估了衍生化反应的效率，发现与纯乙腈相似。当前的衍生化方法是第一个保留氯基团身份并支持HD调节和证据发现的方法。
• Methods of preparation of an olefin oligomerization catalyst
  申请人：Knudsen D. Ronald

  公开号：US20050187391A1

  公开（公告）日：2005-08-25

  A method of making a catalyst for use in oligomerizing an olefin comprising a chromium-containing compound, a pyrrole-containing compound, a metal alkyl, a halide-containing compound, and optionally a solvent, the method comprising contacting a composition comprising the chromium-containing compound and a composition comprising the metal alkyl, wherein the composition comprising the chromium-containing compound is added to the composition comprising the metal alkyl.

  制备用于寡聚烯烃的催化剂的方法包括含铬化合物、含吡咯化合物、金属烷基、含卤化合物和可选的溶剂，该方法包括将含铬化合物的组合物与含金属烷基的组合物接触，其中含铬化合物的组合物被添加到含金属烷基的组合物中。
• [EN] RADIATION CURABLE INKJET INKS FOR INTERIOR DECORATION<br/>[FR] ENCRES POUR JET D'ENCRE DURCISSABLES PAR RAYONNEMENT POUR DÉCORATION INTÉRIEURE
  申请人：AGFA NV

  公开号：WO2020152037A1

  公开（公告）日：2020-07-30

  A radiation curable inkjet ink containing at least one or two compounds selected from the group consisting of a polymerizable compound including a vinylether group or a vinylamide group, an amine synergist including an alkanolamine group or a dimethyl benzoate group, and a Norrish Type II photoinitiator including a photoinitiating moiety selected from the group consisting of a thioxanthone group, a benzophenone group, a ketocoumarin group and a camphorquinone group; and a singlet oxygen quencher including at least one specific amino-thioether group.

  一种辐射固化喷墨墨水，含有至少一种或两种化合物，所选自包括具有乙烯醚基团或乙烯酰胺基团的可聚合化合物、包括烷醇胺基团或二甲基苯甲酸酯基团的胺协同剂以及包括硫氧自由基的光引发剂的诺里斯II型光引发剂，以及包括至少一种特定氨基硫醚基团的单线态氧猝灭剂。
• Trimerisation and oligomerisation of olefins using a chromium based catalyst
  申请人：Dixon Thomas John

  公开号：US20050131262A1

  公开（公告）日：2005-06-16

  The invention provides a mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms, of which at least one heteroatom is sulfur and at least 2 heteroatoms are not the same. The invention also provides a multidentate mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms of which at least one is a sulfur atom. The ligand may also contain, in addition to sulfur, at least one nitrogen or phosphorous heteroatom.

  本发明提供了一种用于烯烃寡聚催化剂的混合杂原子配体，该配体包括至少三个杂原子，其中至少一个杂原子是硫，至少有2个杂原子不相同。本发明还提供了一种多齿混合杂原子配体，用于烯烃寡聚催化剂，该配体包括至少三个杂原子，其中至少一个是硫原子。该配体还可以包含除硫外，至少一个氮或磷杂原子。
• TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST
  申请人：Dixon John Thomas

  公开号：US20080200744A1

  公开（公告）日：2008-08-21

  The invention provides a mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms, of which at least one heteroatom is sulfur and at least two heteroatoms are not the same. The invention also provides a multidentate mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms of which at least one is a sulfur atom. The ligand may also contain, in addition to sulfur, at least one nitrogen or phosphorous heteroatom.

  本发明提供了用于烯烃寡聚催化剂的混合杂原子配体，该配体包括至少三个杂原子，其中至少一个杂原子是硫，至少两个杂原子不相同。本发明还提供了用于烯烃寡聚催化剂的多齿混合杂原子配体，该配体包括至少三个杂原子，其中至少一个是硫原子。配体还可以除硫外，包含至少一个氮或磷杂原子。