N-甲基-2H-四唑-5-胺 | 53010-03-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N-甲基-2H-四唑-5-胺
• 英文名称: N-methyl-1H-tetrazol-5-amine
• 英文别名: 5-methylamino-tetrazole；methyl-(1(2)H-tetrazol-5-yl)-amine；methyl-(1H-tetrazol-5-yl)-amine；Methyl-(1H-tetrazol-5-yl)-amin；5-Methylamino-1H-tetrazole；N-methyl-2H-tetrazol-5-amine
• CAS: 53010-03-0
• 化学式: C₂H₅N₅
• mdl: MFCD03931340
• 分子量: 99.0952
• InChiKey: LQICKCWPFRQEFI-UHFFFAOYSA-N

物化性质

• 熔点：
  185-187 °C
• 沸点：
  250.3±23.0 °C(Predicted)
• 密度：
  1.481±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  66.5
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2933990090

反应信息

• 作为反应物：
  描述：

  N-甲基-2H-四唑-5-胺 生成 1-甲基-5-氨基四氮唑
  参考文献：
  名称：

  Preparation and isomerization of 5-alkylaminotetrazoles

  摘要：

  DOI：

  10.1021/jo50013a002
• 作为产物：
  描述：

  barium(2+);dicyanide 在 钯 、 溶剂黄146 作用下， 生成 N-甲基-2H-四唑-5-胺
  参考文献：
  名称：

  Preparation and isomerization of 5-alkylaminotetrazoles

  摘要：

  DOI：

  10.1021/jo50013a002

文献信息

• HERBICIDAL COMPOUNDS
  申请人：SYNGENTA LIMITED

  公开号：US20140371067A1

  公开（公告）日：2014-12-18

  The present invention relates to a method of controlling weeds at a locus, said method comprising application to the locus of a weed controlling amount of a herbicidal composition comprising a compound of Formula (I), or an agronomically acceptable salt of said compounds wherein X, R 1 , R 2 , R 4 and R 5 are as defined herein. The invention further relates novel herbicidal compounds, to herbicidal compositions comprising said compounds and to their use for controlling weeds, in particular in crops of useful plants.

  本发明涉及一种控制杂草的方法，该方法包括向生长地点施加一种除草剂组合物，该组合物包括式（I）的化合物或其农业上可接受的盐，其中X、R1、R2、R4和R5如本文所定义。本发明还涉及新型除草剂化合物，包括所述化合物的除草剂组合物以及其用于控制杂草的应用，特别是在有用植物的农作物中。
• ANTIFUNGAL AGENTS
  申请人：Greenlee Mark L

  公开号：US20110224228A1

  公开（公告）日：2011-09-15

  Novel derivatives of enfumafungin are disclosed herein, along with' their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and method of using such compounds as antifungal agents and/or inhibitors of (1,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.

  本文披露了恩福马富金的新衍生物，以及它们的药物可接受的盐、水合物和前药。还披露了包含这些化合物的组合物，制备这些化合物的方法以及将这些化合物用作抗真菌剂和/或(1,3)-β-D-葡聚糖合酶的抑制剂的方法。所披露的化合物、它们的药物可接受的盐、水合物和前药，以及包含这些化合物、盐、水合物和前药的组合物，对于治疗和/或预防真菌感染和相关疾病和病况是有用的。
• Antifungal agents
  申请人：Greenlee Mark L.

  公开号：US08722727B2

  公开（公告）日：2014-05-13

  Novel derivatives of enfumafungin are disclosed herein, along with' their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and method of using such compounds as antifungal agents and/or inhibitors of (1,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.

  本文披露了恩富马富金的新衍生物，以及它们的药用盐、水合物和前药。还披露了包含这些化合物的组合物，制备这些化合物的方法以及将这些化合物用作抗真菌剂和/或(1,3)-β-D-葡聚糖合酶抑制剂的方法。这些化合物、它们的药用盐、水合物和前药，以及包含这些化合物、盐、水合物和前药的组合物，有助于治疗和/或预防真菌感染和相关疾病和病症。
• The synthesis of certain 5-aminotetrazole derivatives. I. The action of hydrazoic acid on some dialkylcyanamides
  作者：William L. Garbrecht、Robert M. Herbst

  DOI：10.1021/jo50014a015

  日期：1953.8
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ag: MVol.B6, 1.5.4.1, page 191 - 196
  作者：

  DOI：——

  日期：——