2-Ethyl-2-[3-(trifluoromethyl)phenyl]butanamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Ethyl-2-[3-(trifluoromethyl)phenyl]butanamide
• 英文别名: 2-ethyl-2-[3-(trifluoromethyl)phenyl]butanamide
• 化学式: C₁₃H₁₆F₃NO
• 分子量: 259.27
• InChiKey: QWOHYEHIIJCUEB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] CYCLIC AZA-SILA COMPOUNDS AS INSECT REPELLANTS<br/>[FR] COMPOSÉS AZA-SILA CYCLIQUES UTILISÉS EN TANT QU'INSECTIFUGES
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2014097322A1

  公开（公告）日：2014-06-26

  The invention relates to aza-sila compounds of Formula (I), useful as insect repellants. wherein, 'A' is selected from the group consisting of branched or unbranched (C I -CI 2) alkyl, branched or unbranched (CI -CI 2) alkynyl; and substituted or unsubstituted 4 to 6 membered acyclic saturated or unsaturated compounds, wherein the substituents are selected from the group consisting of halogen, hydrogen, (CI -C6) alkyl, aryl, arylalkyl and heterocyclic; or ' A' is independently selected from the group consisting of the following moiety: Formula (II) wherein, X and Y are identical or different and independently selected from the group consisting of-C-, -N, -O, and -S; where Rl, R2, R3, and R4 are identical or different and are independently selected from the group consisting of hydrogen, halogen, linear or branched (C1-C6) alkyl, aryl, arylalkyl, hydroxyl, and heterocyclic; and wherein, the halogen is selected from the group consisting of—CI, -I, -Br, and -F. The invention further discloses a process for the preparation of the compounds of Formula (I).