4-Fluoro-3-methyl-5-phenoxycyclohexa-1,5-diene-1-carbaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Fluoro-3-methyl-5-phenoxycyclohexa-1,5-diene-1-carbaldehyde
• 英文别名: 4-fluoro-3-methyl-5-phenoxycyclohexa-1,5-diene-1-carbaldehyde
• 化学式: C₁₄H₁₃FO₂
• 分子量: 232.25
• InChiKey: NHUGWFVHZSXSJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] FLUORESCENT CELL CYCLE PROBE HAVING M-PHASE SPECIFICITY<br/>[FR] SONDE FLUORESCENTE DE CYCLE CELLULAIRE POSSÉDANT UNE SPÉCIFICITÉ DE PHASE M
  申请人：NAT UNIVERISTY OF SINGAPORE

  公开号：WO2014109713A1

  公开（公告）日：2014-07-17

  The present invention is directed to a novel family of fluorophores based on the BODIPY scaffold, and methods for their synthesis. The BODIPY-based fluorophores disclosed herein are used for the selective visualization of cells that exist in the M-phase of the cell cycle. The present invention further relates to methods for the image-based monitoring of mitotic progression in live cells.