2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]imidazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]imidazole
• 英文别名: 2-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]imidazole
• 化学式: C₁₂H₉ClN₂S₂
• 分子量: 280.8
• InChiKey: QAIPMEXGUGYCDJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  75.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• PHARMACEUTICAL COMPOSITION FOR DISEASES CAUSED BY PATHOGENIC MICROORGANISMS SUCH AS ASPERGILLUS
  申请人：Pola Pharma Inc.

  公开号：EP2948145A1

  公开（公告）日：2015-12-02
• [EN] PHARMACEUTICAL COMPOSITION FOR DISEASES CAUSED BY PATHOGENIC MICROORGANISMS SUCH AS ASPERGILLUS<br/>[FR] COMPOSITION PHARMACEUTIQUE DESTINÉES À DES MALADIES PROVOQUÉES PAR DES MICROORGANISMES PATHOGÈNES TELS QU'ASPERGILLUS
  申请人：POLA PHARMA INC

  公开号：WO2014115487A1

  公开（公告）日：2014-07-31

  An object is to provide means for precisely treating pneumonia caused by intracellular parasite, protozoa, and/or fungus. A pharmaceutical composition for pneumonia, comprising a compound represented by the following general formula (1) as an active ingredient:(In the formula, R represents a halogen atom or a hydrogen atom, and X represents a halogen atom.)
• [EN] PHARMACEUTICAL COMPOSITION FOR TREATING VAGINITIS OR PNEUMONIA<br/>[FR] COMPOSITION PHARMACEUTIQUE POUR TRAITER UNE VAGINITE OU UNE PNEUMONIE
  申请人：POLA PHARMA INC

  公开号：WO2014185542A1

  公开（公告）日：2014-11-20

  Provided is a pharmaceutical composition in which an action of a compound represented by a general formula (1) is enhanced, and which is effective for pneumonia and vaginitis. Disclosed is a pharmaceutical composition for vaginitis or pneumonia, comprising a compound represented by the following general formula (1) and crotamiton: (in the formula, each of R1 and R2 independently represents hydrogen atom or halogen atom, and R1 and R2 are not simultaneously hydrogen atoms.)