tert-butyl N-[4-(3-dimethylphosphoryl-2-oxopropyl)phenyl]carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tert-butyl N-[4-(3-dimethylphosphoryl-2-oxopropyl)phenyl]carbamate
• 化学式: C₁₆H₂₄NO₄P
• 分子量: 325.34
• InChiKey: SNIIMBRFCGTTAS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  72.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES
  申请人：Chung John Y.L.

  公开号：US20140242645A1

  公开（公告）日：2014-08-28

  The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions.
• Process for Making Beta 3 Agonists and Intermediates
  申请人：Merck Sharp & Dohme Corp.

  公开号：US20160176884A1

  公开（公告）日：2016-06-23

  The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
• US9822121B2
  申请人：——

  公开号：US9822121B2

  公开（公告）日：2017-11-21
• US9809536B2
  申请人：——

  公开号：US9809536B2

  公开（公告）日：2017-11-07