[(3S)-3-[(4-bromophenyl)carbamoylamino]-5-methyl-2-oxopyrrolidin-1-yl]methyl-ethoxyphosphinic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(3S)-3-[(4-bromophenyl)carbamoylamino]-5-methyl-2-oxopyrrolidin-1-yl]methyl-ethoxyphosphinic acid
• 化学式: C₁₅H₂₁BrN₃O₅P
• 分子量: 434.22
• InChiKey: LYWXUEKMKABVJW-HQVZTVAUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  108
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES<br/>[FR] UTILISATION D'AGONISTES DU RÉCEPTEUR 2 DE PEPTIDE FORMYLE POUR LE TRAITEMENT DE MALADIES DERMATOLOGIQUES
  申请人：ALLERGAN INC

  公开号：WO2014138046A1

  公开（公告）日：2014-09-12

  The present invention relates to a method for treating dermal inflammation and dermal diseases by local or systemic delivery, in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of Formyl peptide receptor 2 (FPR2).
• [EN] USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES<br/>[FR] UTILISATION D'AGONISTES DU RÉCEPTEUR 2 DE PEPTIDE FORMYLE POUR LE TRAITEMENT DE MALADIES INFLAMMATOIRES OCULAIRES
  申请人：ALLERGAN INC

  公开号：WO2014138037A1

  公开（公告）日：2014-09-12

  The present invention relates to a method for treating ocular inflammatory diseases in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of Formyl peptide receptor 2.