pentane-2,4-dione;N-phenylformamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: pentane-2,4-dione;N-phenylformamide
• 化学式: C12H15NO3
• 分子量: 221.25
• InChiKey: BQMGCPOJGJWTPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.81
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  63.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• US20140275271A1
  申请人：——

  公开号：US20140275271A1

  公开（公告）日：2014-09-18
• NOVEL MODIFIED CURCUMINS AND THEIR USES
  申请人：GOLUB Lorne M.

  公开号：US20160355465A1

  公开（公告）日：2016-12-08

  This invention provides a compound having the structure wherein α, β, A, B, and R 1 -R 4 are defined herein. This invention also provides pharmaceutical compositions comprising the above compounds, a method of accelerating the healing of a wound, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NFκ-B activation in a population of cells.